Development Level

Tbio 50 | 11,445
Tchem 31 | 1,598
Tclin 12 | 613

IMPC Phenotype

preweaning lethality, complete... 4 | 979
increased circulating choleste... 3 | 66
preweaning lethality, incomple... 3 | 499
abnormal bone mineralization 2 | 38
abnormal skin morphology 2 | 50
decreased body weight 2 | 161
decreased circulating amylase ... 2 | 28
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased mean corpuscular vol... 2 | 79
enlarged heart 2 | 210
female infertility 2 | 60
impaired glucose tolerance 2 | 75
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating triglyce... 2 | 42
male infertility 2 | 123
persistence of hyaloid vascula... 2 | 33
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal glucose homeostasis 1 | 4
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
absent testes 1 | 6
decreased circulating LDL chol... 1 | 38
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating phosphat... 1 | 26
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 72 | 11,493
Cancer 66 | 2,499
ovarian cancer 61 | 8,520
glioblastoma 49 | 5,792
psoriasis 48 | 6,694
osteosarcoma 46 | 7,950
lung cancer 43 | 4,740
Breast cancer 41 | 3,578
medulloblastoma, large-cell 39 | 6,241
malignant mesothelioma 37 | 3,232
atypical teratoid / rhabdoid tumor 35 | 5,112
Kidney cancer 31 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
pancreatic cancer 28 | 2,398
ependymoma 27 | 4,679
primitive neuroectodermal tumor 26 | 3,035
Astrocytoma, Pilocytic 24 | 3,081
group 3 medulloblastoma 24 | 4,104
invasive ductal carcinoma 24 | 2,951
oligodendroglioma 24 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
non-small cell lung cancer 23 | 2,890
adult high grade glioma 22 | 3,801
cystic fibrosis 22 | 1,696
lung carcinoma 22 | 2,843
nasopharyngeal carcinoma 22 | 1,058
subependymal giant cell astrocytoma 22 | 2,287
Autosomal recessive predisposition 21 | 1,442
lung adenocarcinoma 21 | 2,716
Breast Neoplasms 20 | 445
Mammary Neoplasms 20 | 425
juvenile dermatomyositis 20 | 1,187
Prostatic Neoplasms 19 | 495
adrenocortical carcinoma 19 | 1,428
ductal carcinoma in situ 19 | 1,745
tuberculosis 19 | 2,010
breast carcinoma 18 | 1,638
dermatomyositis 18 | 966
Schizophrenia 17 | 1,160
acute quadriplegic myopathy 16 | 1,158
interstitial cystitis 16 | 2,312
ulcerative colitis 16 | 1,819
Carcinoma, Hepatocellular 15 | 228
Liver carcinoma 15 | 240
Stomach Neoplasms 15 | 300
astrocytoma 15 | 1,146
diabetes mellitus 15 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Lung Neoplasms 14 | 232
Melanoma 14 | 711
Rheumatoid arthritis 14 | 1,191
Seizures 14 | 596
colon cancer 14 | 1,478
pituitary cancer 14 | 1,972
primary pancreatic ductal adenocarcinoma 14 | 1,109
acute myeloid leukemia 13 | 783
Adenoma 12 | 167
Epilepsy 12 | 792
Kidney disease 12 | 430
Liver Cirrhosis, Experimental 12 | 769
Vascular disease 12 | 319
group 4 medulloblastoma 12 | 1,855
Colonic Neoplasms 11 | 142
Endometriosis 11 | 540
Multiple myeloma 11 | 1,332
Myopia 11 | 176
Anemia 10 | 365
Arthritis 10 | 290
Brain Ischemia 10 | 110
Cataract 10 | 297
Cell Transformation, Neoplastic 10 | 97
Duchenne muscular dystrophy 10 | 601
Endometrial cancer 10 | 311
Hypertensive disease 10 | 292
Intellectual disability 10 | 1,016
Liver cancer 10 | 604
Squamous cell carcinoma 10 | 129
esophageal adenocarcinoma 10 | 737
gastric carcinoma 10 | 807
medulloblastoma 10 | 720
Adenocarcinoma 9 | 122
Carcinoma, Squamous Cell 9 | 110
Dull intelligence 9 | 645
Hypertension 9 | 396
Lens Opacities 9 | 231
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Neoplastic Cell Transformation 9 | 89
Ovarian Neoplasms 9 | 102
Poor school performance 9 | 645
Renal Cell Carcinoma 9 | 214
active ulcerative colitis 9 | 764
pediatric high grade glioma 9 | 1,064
Alzheimer's disease 8 | 658
Pick disease 8 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
cutaneous lupus erythematosus 8 | 1,057
hepatocellular carcinoma 8 | 547

Tissue

Endocrine System 93 | 18,159
Blood and immune system 92 | 16,909
Digestive Tract 92 | 17,369
Female tissues 92 | 17,400
Liver and Pancreas 92 | 16,750
Male tissues 92 | 17,142
Nervous System 92 | 16,725
Respiratory system 92 | 16,393
Skin and soft tissues 92 | 17,230
Urinary Tract 92 | 16,678
Cardiovascular System 90 | 15,192

Target Family

Non-IDG 49 | 12,091
Enzyme 17 | 4,145
Kinase 14 | 634
Transcription Factor 9 | 1,400
Nuclear Receptor 4 | 48

KEGG Pathway

Small cell lung cancer 93 | 93
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibronectin FN1 Tchem Non-IDG -3.09873 1208.8 1583
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
TNF receptor-associated factor 4 TRAF4 Tbio Non-IDG -1.67380 54.4 234
Laminin subunit beta-4 LAMB4 Tbio Non-IDG -0.78478 6.19 13
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.35134 2277.5 752
Laminin subunit gamma-1 LAMC1 Tbio Non-IDG -1.79184 56.7 318
Cytochrome c CYCS Tbio Non-IDG -3.76637 4945.6 833
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731
Retinoic acid receptor RXR-beta RXRB Tclin Nuclear Receptor -1.72557 49.3 274
Focal adhesion kinase 1 PTK2 Tchem Kinase -3.06733 1038.3 2013