Development Level

Tbio 38 | 11,445
Tchem 18 | 1,598
Tclin 6 | 613
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 4 | 499
increased leukocyte cell numbe... 3 | 47
abnormal bone structure 2 | 187
abnormal cornea morphology 2 | 31
abnormal retina morphology 2 | 71
corneal opacity 2 | 32
decreased circulating fructosa... 2 | 30
decreased circulating serum al... 2 | 82
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
increased circulating alkaline... 2 | 122
increased mean corpuscular vol... 2 | 92
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal femur morphology 1 | 14
abnormal hair texture 1 | 4
abnormal skin condition 1 | 6
abnormal stomach morphology 1 | 10
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased mean corpuscular hem... 1 | 31
decreased spleen weight 1 | 10
decreased thermal nociceptive ... 1 | 2
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
fused cornea and lens 1 | 5
fusion of vertebral arches 1 | 7
increased circulating amylase ... 1 | 25
increased circulating free fat... 1 | 20
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased thermal nociceptive ... 1 | 9
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 39 | 11,493
ovarian cancer 39 | 8,520
glioblastoma 34 | 5,792
osteosarcoma 34 | 7,950
Cancer 33 | 2,499
atypical teratoid / rhabdoid tumor 27 | 5,112
psoriasis 24 | 6,694
medulloblastoma, large-cell 21 | 6,241
ependymoma 20 | 4,679
lung cancer 18 | 4,740
Astrocytoma, Pilocytic 17 | 3,081
adult high grade glioma 16 | 3,801
subependymal giant cell astrocytoma 16 | 2,287
astrocytic glioma 14 | 2,597
group 4 medulloblastoma 14 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
oligodendroglioma 13 | 2,850
diabetes mellitus 12 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
lung carcinoma 12 | 2,843
malignant mesothelioma 12 | 3,232
tuberculosis 12 | 2,010
Arthritis 11 | 290
Breast cancer 11 | 3,578
Multiple myeloma 11 | 1,332
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
invasive ductal carcinoma 11 | 2,951
pancreatic cancer 11 | 2,398
Vascular disease 10 | 319
astrocytoma 10 | 1,146
group 3 medulloblastoma 10 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
primitive neuroectodermal tumor 10 | 3,035
Kidney cancer 9 | 2,613
Rheumatoid arthritis 9 | 1,191
Schizophrenia 9 | 1,160
colon cancer 9 | 1,478
interstitial cystitis 9 | 2,312
ulcerative colitis 9 | 1,819
Intellectual disability 8 | 1,016
Pick disease 8 | 1,894
Waldenstrons macroglobulinemia 8 | 765
posterior fossa group A ependymoma 8 | 468
primary pancreatic ductal adenocarcinoma 8 | 1,109
Kidney disease 7 | 430
Neoplasm Invasiveness 7 | 161
Small head 7 | 374
Stomach Neoplasms 7 | 300
adrenocortical carcinoma 7 | 1,428
esophageal adenocarcinoma 7 | 737
juvenile dermatomyositis 7 | 1,187
lung adenocarcinoma 7 | 2,716
medulloblastoma 7 | 720
pediatric high grade glioma 7 | 1,064
Bipolar Disorder 6 | 666
Brain Ischemia 6 | 110
Carcinoma, Squamous Cell 6 | 110
Cell Transformation, Neoplastic 6 | 97
Down syndrome 6 | 499
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Neoplasm Metastasis 6 | 168
Neoplastic Cell Transformation 6 | 89
Obesity 6 | 678
Poor school performance 6 | 645
Short stature 6 | 531
Squamous cell carcinoma 6 | 129
gastric cancer 6 | 459
Breast Neoplasms 5 | 445
Cardiomyopathies 5 | 110
Cholestasis, Extrahepatic 5 | 25
Colitis, Ulcerative 5 | 59
Crohn's disease 5 | 321
Depressive disorder 5 | 409
Heart disease 5 | 306
Hyperalgesia 5 | 83
Hypertension 5 | 396
Immunologic Deficiency Syndromes 5 | 113
Inflammatory bowel disease 5 | 151
Liver Cirrhosis, Experimental 5 | 769
Lung Neoplasms 5 | 232
Lung disease 5 | 142
Mammary Neoplasms 5 | 425
Mental Depression 5 | 333
Neurodegenerative disease 5 | 414
Osteoporosis 5 | 363
Reperfusion Injury 5 | 86
Wiskott-Aldrich syndrome 5 | 30
acute myeloid leukemia 5 | 783
dermatomyositis 5 | 966
ductal carcinoma in situ 5 | 1,745
non primary Sjogren syndrome sicca 5 | 891
non-small cell lung cancer 5 | 2,890
pituitary cancer 5 | 1,972
Duchenne muscular dystrophy 4 | 601
Myocardial Ischemia 4 | 169
acute quadriplegic myopathy 4 | 1,158
spina bifida 4 | 1,074

Tissue

Endocrine System 65 | 18,159
Urinary Tract 65 | 16,678
Blood and immune system 64 | 16,909
Cardiovascular System 64 | 15,192
Digestive Tract 64 | 17,369
Female tissues 64 | 17,400
Liver and Pancreas 64 | 16,750
Male tissues 64 | 17,142
Nervous System 64 | 16,725
Respiratory system 64 | 16,393
Skin and soft tissues 64 | 17,230

Target Family

Non-IDG 43 | 12,091
Kinase 17 | 634
Enzyme 3 | 4,145
Transcription Factor 2 | 1,400

KEGG Pathway

Shigellosis 65 | 65
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Splicing factor U2AF 26 kDa subunit U2AF1L4 Tbio Non-IDG -0.17609 1.86 61
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Tclin Non-IDG -3.13621 1445.5 370
Splicing factor U2AF 35 kDa subunit-like protein U2AF1 Tbio Non-IDG -1.71712 73.6 0
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Wiskott-Aldrich syndrome protein family member 2 WASF2 Tbio Non-IDG -2.90666 762.6 254
Profilin-4 PFN4 Tdark Non-IDG -0.52386 3.41 23
Actin-related protein 2/3 complex subunit 2 ARPC2 Tbio Non-IDG -1.31089 16.9 270
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380
Actin-related protein 2/3 complex subunit 4 ARPC4 Tbio Non-IDG -1.00650 0.00000 120