Development Level

Tbio 50 | 10,625
Tchem 26 | 1,890
Tclin 4 | 602
Tdark 4 | 7,003

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 4 | 633
decreased body weight 3 | 174
decreased circulating fructosa... 3 | 31
decreased total body fat amoun... 3 | 186
increased leukocyte cell numbe... 3 | 37
decreased bone mineral content 2 | 157
decreased circulating sodium l... 2 | 18
decreased hematocrit 2 | 25
decreased lean body mass 2 | 195
decreased leukocyte cell numbe... 2 | 54
improved glucose tolerance 2 | 56
increased circulating alkaline... 2 | 119
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal coat/hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal hair texture 1 | 4
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal skin coloration 1 | 18
abnormal skin condition 1 | 6
absent pinna reflex 1 | 21
decreased circulating amylase ... 1 | 24
decreased circulating choleste... 1 | 85
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased thermal nociceptive ... 1 | 4
edema 1 | 11
embryonic lethality prior to t... 1 | 187
fused cornea and lens 1 | 4
fusion of vertebral arches 1 | 7
hemorrhage 1 | 12
hydrops fetalis 1 | 22
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
increased body weight 1 | 42
increased circulating amylase ... 1 | 13
increased circulating free fat... 1 | 17
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased red blood cell distr... 1 | 21
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 57
prenatal lethality prior to he... 1 | 64
vertebral fusion 1 | 23

Disease

ovarian cancer 48 | 8,484
psoriasis 44 | 6,685
glioblastoma 41 | 5,572
osteosarcoma 38 | 7,933
Cancer 34 | 2,346
lung cancer 30 | 4,466
tuberculosis 30 | 1,557
lung carcinoma 27 | 2,844
atypical teratoid / rhabdoid tumor 25 | 4,369
medulloblastoma, large-cell 25 | 6,234
pilocytic astrocytoma 25 | 3,086
malignant mesothelioma 23 | 3,162
Arthritis 21 | 248
diabetes mellitus 21 | 1,663
pediatric high grade glioma 20 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
pancreatic cancer 19 | 2,300
ulcerative colitis 19 | 2,087
astrocytoma 18 | 1,493
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
Asthma 17 | 349
Lung disease 17 | 132
Vascular disease 17 | 281
subependymal giant cell astrocytoma 17 | 2,287
Kidney disease 16 | 396
lung adenocarcinoma 16 | 2,713
Carcinoma 15 | 2,147
Inflammatory bowel disease 15 | 142
Multiple Sclerosis 15 | 498
Reperfusion Injury 15 | 84
Rheumatoid Arthritis 15 | 1,160
invasive ductal carcinoma 15 | 2,950
non-small cell lung cancer 15 | 2,798
Breast cancer 14 | 3,094
adult high grade glioma 14 | 2,148
cystic fibrosis 14 | 1,665
interstitial cystitis 14 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,988
Brain Ischemia 13 | 87
Inflammation 13 | 109
Multiple myeloma 13 | 1,327
Obesity 13 | 616
Pneumonia 13 | 133
cutaneous lupus erythematosus 13 | 1,056
Influenza 12 | 142
Lung Neoplasms 12 | 171
Mammary Neoplasms 12 | 410
colon cancer 12 | 1,475
esophageal adenocarcinoma 12 | 737
Dermatitis 11 | 107
Eye disease 11 | 55
Hypersensitivity reaction type II disease 11 | 235
ependymoma 11 | 2,514
group 4 medulloblastoma 11 | 1,875
juvenile dermatomyositis 11 | 1,189
medulloblastoma 11 | 1,524
posterior fossa group A ependymoma 11 | 1,511
primitive neuroectodermal tumor 11 | 3,031
Atherosclerosis 10 | 275
Heart disease 10 | 279
Myocardial Ischemia 10 | 169
Neoplastic Cell Transformation 10 | 81
Peritonitis 10 | 37
Waldenstrons macroglobulinemia 10 | 765
astrocytic glioma 10 | 2,241
hepatocellular carcinoma 10 | 532
oligodendroglioma 10 | 2,849
Alzheimer's disease 9 | 644
Liver disease 9 | 219
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
periodontitis 9 | 269
primary pancreatic ductal adenocarcinoma 9 | 1,271
spina bifida 9 | 1,064
Allergic hypersensitivity disease 8 | 123
Cholestasis 8 | 93
Hypersensitivity 8 | 63
Leishmaniasis 8 | 49
Liver carcinoma 8 | 217
Malaria 8 | 140
Pick disease 8 | 1,893
Stomach Neoplasms 8 | 282
adrenocortical carcinoma 8 | 1,427
breast carcinoma 8 | 1,614
gastric cancer 8 | 430
gastric carcinoma 8 | 832
Cardiomyopathies 7 | 90
Endometriosis 7 | 535
Eosinophilia 7 | 65
Hyperalgesia 7 | 71
Hypertension 7 | 287
Keratitis 7 | 42
Neurodegenerative disease 7 | 383
Neuropathy 7 | 210
Parkinson's disease 7 | 364
Peripheral Neuropathy 7 | 303
Prostatic Neoplasms 7 | 471
Toxic encephalopathy 7 | 131
acute myeloid leukemia 7 | 780
atypical teratoid/rhabdoid tumor 7 | 1,095
pituitary cancer 7 | 1,972

Tissue

Digestive Tract 80 | 18,473
Nervous System 80 | 18,561
Urinary Tract 80 | 18,444
Blood and immune system 79 | 17,995
Cardiovascular System 79 | 17,958
Endocrine System 79 | 18,512
Female tissues 79 | 18,647
Liver and Pancreas 79 | 18,136
Respiratory system 79 | 17,484
Skin and soft tissues 79 | 18,115
Male tissues 78 | 17,969

Target Family

Non-IDG 59 | 11,971
Kinase 14 | 634
Enzyme 7 | 4,146
Transcription Factor 4 | 1,400

KEGG Pathway

Salmonella infection 84 | 84
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Serine/threonine-protein kinase N3 PKN3 Tchem Kinase -1.11681 14.4 104
Pleckstrin homology domain-containing family M member 2 PLEKHM2 Tbio Non-IDG -0.22831 2.68 56
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.60609 403.7 216
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.32560 2206.3 649
Profilin-4 PFN4 Tdark Non-IDG -0.52386 3.41 21
Mitogen-activated protein kinase 13 MAPK13 Tchem Kinase -2.46715 317.1 405
Profilin-2 PFN2 Tbio Non-IDG -1.92449 89.6 196
C-C motif chemokine 4-like CCL4L2 Tbio Non-IDG -2.01543 361.7 43