Development Level

Tbio 44 | 11,445
Tclin 25 | 613
Tchem 17 | 1,598
Tdark 4 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
abnormal bone structure 4 | 187
increased heart weight 4 | 62
increased startle reflex 4 | 112
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
abnormal seminal vesicle morph... 2 | 114
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
hyperactivity 2 | 148
small superior vagus ganglion 2 | 74
abnormal duodenum morphology 1 | 4
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal gallbladder morpholog... 1 | 1
abnormal locomotor behavior 1 | 24
abnormal vibrissa morphology 1 | 25
abnormal vocalization 1 | 21
absent vibrissae 1 | 12
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged gallbladder 1 | 2
enlarged heart 1 | 210
enlarged spleen 1 | 41
hydrometra 1 | 53
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
small epididymis 1 | 3

Disease

Carcinoma 60 | 11,493
psoriasis 50 | 6,694
medulloblastoma, large-cell 40 | 6,241
ovarian cancer 40 | 8,520
glioblastoma 39 | 5,792
lung cancer 37 | 4,740
atypical teratoid / rhabdoid tumor 36 | 5,112
osteosarcoma 36 | 7,950
Kidney cancer 34 | 2,613
adult high grade glioma 33 | 3,801
ependymoma 33 | 4,679
group 3 medulloblastoma 30 | 4,104
Breast cancer 29 | 3,578
Astrocytoma, Pilocytic 27 | 3,081
primitive neuroectodermal tumor 27 | 3,035
lung adenocarcinoma 26 | 2,716
astrocytic glioma 25 | 2,597
lung carcinoma 25 | 2,843
pancreatic cancer 25 | 2,398
Hypertension 22 | 396
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
oligodendroglioma 21 | 2,850
colon cancer 19 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
non-small cell lung cancer 19 | 2,890
Cancer 17 | 2,499
Pick disease 17 | 1,894
invasive ductal carcinoma 17 | 2,951
diabetes mellitus 16 | 1,728
pituitary cancer 16 | 1,972
interstitial cystitis 15 | 2,312
subependymal giant cell astrocytoma 15 | 2,287
tuberculosis 15 | 2,010
ulcerative colitis 15 | 1,819
Parkinson's disease 14 | 392
Schizophrenia 14 | 1,160
chronic rhinosinusitis 14 | 512
malignant mesothelioma 14 | 3,232
Chronic heart failure 13 | 46
Epilepsy 13 | 792
Hypertensive disease 13 | 292
cystic fibrosis 13 | 1,696
Bipolar Disorder 12 | 666
Liver cancer 12 | 604
Obesity 12 | 678
Kidney disease 11 | 430
Asthma 10 | 385
Atrial Fibrillation 10 | 124
Autosomal recessive predisposition 10 | 1,442
group 4 medulloblastoma 10 | 1,855
Congestive heart failure 9 | 113
Depressive disorder 9 | 409
Hypertensive disorder 9 | 56
Major Depressive Disorder 9 | 301
cutaneous lupus erythematosus 9 | 1,057
ductal carcinoma in situ 9 | 1,745
Bronchitis 8 | 43
Heart disease 8 | 306
Melanoma 8 | 711
Poisoning by digitalis glycoside 8 | 8
Unipolar Depression 8 | 250
breast carcinoma 8 | 1,638
Adenoma 7 | 167
Autistic Disorder 7 | 364
Cerebrovascular disease 7 | 238
Dental caries 7 | 164
Duchenne muscular dystrophy 7 | 601
Mood Disorders 7 | 184
Waldenstrons macroglobulinemia 7 | 765
astrocytoma 7 | 1,146
primary pancreatic ductal adenocarcinoma 7 | 1,109
Alzheimer's disease 6 | 658
Bronchiectasis 6 | 64
Carney complex 6 | 25
Chronic Lymphocytic Leukemia 6 | 262
Chronic obstructive pulmonary disease 6 | 184
Common cold 6 | 67
Coronary artery disease 6 | 268
Essential Hypertension 6 | 94
Intellectual disability 6 | 1,016
Multiple Sclerosis 6 | 540
Open-angle glaucoma 6 | 27
Orthostatic hypotension 6 | 9
Osteoporosis 6 | 363
Pulmonary emphysema 6 | 48
Rheumatoid arthritis 6 | 1,191
Rhinitis 6 | 54
Seizures 6 | 596
Skin cancer 6 | 469
Substance Withdrawal Syndrome 6 | 55
gastric carcinoma 6 | 807
progressive supranuclear palsy 6 | 676
Allergic rhinitis 5 | 94
Atopic dermatitis 5 | 952
Glaucoma 5 | 239
Mental Depression 5 | 333
Prostatic Neoplasms 5 | 495
esophageal adenocarcinoma 5 | 737
pancreatic carcinoma 5 | 562

Tissue

Endocrine System 86 | 18,159
Digestive Tract 85 | 17,369
Female tissues 83 | 17,400
Liver and Pancreas 83 | 16,750
Skin and soft tissues 82 | 17,230
Blood and immune system 80 | 16,909
Male tissues 80 | 17,142
Cardiovascular System 74 | 15,192
Nervous System 74 | 16,725
Respiratory system 73 | 16,393
Urinary Tract 73 | 16,678

Target Family

Non-IDG 29 | 12,091
Enzyme 23 | 4,145
Transporter 15 | 473
Ion Channel 8 | 344
Kinase 8 | 634
GPCR 7 | 408

KEGG Pathway

Salivary secretion 90 | 90
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Mucin-5B MUC5B Tbio Non-IDG -3.20322 1552.2 177
Sodium/potassium-transporting ATPase subunit gamma FXYD2 Tclin Enzyme -1.58017 39.0 64
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Alpha-1D adrenergic receptor ADRA1D Tclin GPCR -2.25789 174.5 120
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Anion exchange protein 2 SLC4A2 Tbio Transporter -1.53800 24.1 77