Development Level

Tbio 30 | 10,625
Tdark 4 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
decreased circulating insulin ... 3 | 75
abnormal behavior 2 | 226
decreased circulating glucose ... 2 | 121
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased bone mineral content 2 | 92
increased lean body mass 2 | 107
abnormal QRS complex 1 | 25
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal sleep behavior 1 | 63
abnormal testis morphology 1 | 30
absent vibrissae 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating triglyce... 1 | 83
decreased effector memory CD4-... 1 | 6
decreased fasted circulating g... 1 | 49
decreased gamma-delta T cell n... 1 | 18
decreased granulocyte number 1 | 8
decreased late germinal center... 1 | 2
decreased lumbar vertebrae num... 1 | 62
decreased monocyte cell number 1 | 28
decreased myeloid cell number ... 1 | 1
decreased pre-pro B cell numbe... 1 | 2
decreased pro-B cell number 1 | 2
decreased rib number 1 | 59
embryonic growth retardation 1 | 28
enlarged epididymis 1 | 27
immune system phenotype 1 | 17
increased B cell number 1 | 23
increased T cell number 1 | 15
increased body weight 1 | 42
increased bone mineral density 1 | 52
increased early germinal cente... 1 | 2
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased immature B cell numb... 1 | 1
increased mature B cell number 1 | 12
increased or absent threshold ... 1 | 128
increased pre-B cell number 1 | 1
increased sacral vertebrae num... 1 | 62
limb grasping 1 | 35
shortened RR interval 1 | 19

Disease

ovarian cancer 21 | 8,492
osteosarcoma 18 | 7,933
medulloblastoma, large-cell 16 | 6,234
psoriasis 15 | 6,685
glioblastoma 11 | 5,572
group 4 medulloblastoma 10 | 1,875
Tetanus 8 | 66
lung cancer 8 | 4,473
pilocytic astrocytoma 8 | 3,086
atypical teratoid / rhabdoid tumor 7 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
malignant mesothelioma 7 | 3,163
Pick disease 6 | 1,893
astrocytoma 6 | 1,493
ependymoma 6 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
invasive ductal carcinoma 6 | 2,950
oligodendroglioma 6 | 2,849
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
tuberculosis 6 | 1,563
Multiple myeloma 5 | 1,328
Vici syndrome 5 | 16
ductal carcinoma in situ 5 | 1,745
group 3 medulloblastoma 5 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
pediatric high grade glioma 5 | 2,712
tuberculosis and treatment for 6 months 5 | 686
Diarrhea 4 | 155
cystic fibrosis 4 | 1,670
dermatomyositis 4 | 967
gastric cancer 4 | 436
lung adenocarcinoma 4 | 2,714
lung carcinoma 4 | 2,844
non primary Sjogren syndrome sicca 4 | 840
non-small cell lung cancer 4 | 2,798
pancreatic cancer 4 | 2,300
pancreatic carcinoma 4 | 567
posterior fossa group B ependymoma 4 | 1,530
Alzheimer's disease 3 | 644
Gaucher disease type 1 3 | 171
acute quadriplegic myopathy 3 | 1,157
astrocytic glioma 3 | 2,241
atypical teratoid/rhabdoid tumor 3 | 1,095
juvenile dermatomyositis 3 | 1,189
primitive neuroectodermal tumor 3 | 3,031
progressive supranuclear palsy 3 | 674
spina bifida 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
Anemia 2 | 252
Batten disease 2 | 15
Botulism 2 | 20
Colitis 2 | 46
Down syndrome 2 | 548
Epilepsy 2 | 346
Gastroenteritis 2 | 46
Heart disease 2 | 279
IGA Glomerulonephritis 2 | 454
Kidney failure 2 | 41
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 918
adrenocortical carcinoma 2 | 1,427
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
axial spondyloarthropathy 2 | 28
breast carcinoma 2 | 1,614
diabetes mellitus 2 | 1,663
hemolytic-uremic syndrome 2 | 28
pituitary cancer 2 | 1,972
ulcerative colitis 2 | 2,087
Androgenic alopecia 1 | 10
Animal Mammary Neoplasms 1 | 136
Autistic Disorder 1 | 320
Blood pressure finding 1 | 56
COPD 1 | 116
Ceroid lipofuscinosis, neuronal, 6 1 | 7
Chediak-Higashi syndrome 1 | 24
Chromosome 17q11.2 deletion syndrome, 1.4Mb 1 | 14
Colorectal Cancer 1 | 62
Colorectal Neoplasms 1 | 217
Hemolytic anemia 1 | 70
Hermansky-Pudlak syndrome 1 | 43
Hyperphosphatemia 1 | 32
Hypohidrosis 1 | 13
Intracranial aneurysm 1 | 20
Leukopenia 1 | 42
MEDNIK syndrome 1 | 8
Mammary Neoplasms, Experimental 1 | 150
Melanoma 1 | 261
Neurodegenerative disease 1 | 383
Neuropathy 1 | 210
Osteoporosis 1 | 259
Pseudohypoaldosteronism 1 | 22
Pulmonary Embolism 1 | 45
Systemic arterial pressure 1 | 56
Thrombocytopenia 1 | 105
Velocardiofacial syndrome 1 | 45
Visual epilepsy 1 | 4
Vitiligo 1 | 71
active ulcerative colitis 1 | 477
chorea-acanthocytosis 1 | 11

Tissue

Blood and immune system 34 | 17,995
Cardiovascular System 34 | 17,958
Digestive Tract 34 | 18,473
Endocrine System 34 | 18,512
Female tissues 34 | 18,647
Liver and Pancreas 34 | 18,136
Male tissues 34 | 17,969
Nervous System 34 | 18,561
Respiratory system 34 | 17,484
Urinary Tract 34 | 18,444
Skin and soft tissues 33 | 18,115

Target Family

Non-IDG 34 | 11,969

KEGG Pathway

SNARE interactions in vesicula... 34 | 34
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Syntaxin-4 STX4 Tbio Non-IDG -1.93051 79.1 192
Vesicle-associated membrane protein 8 VAMP8 Tbio Non-IDG -1.74294 59.3 105
Synaptosomal-associated protein 29 SNAP29 Tbio Non-IDG -1.38923 23.6 114
Vesicle transport protein SEC20 BNIP1 Tbio Non-IDG -1.25063 18.7 257
Vesicle-associated membrane protein 7 VAMP7 Tbio Non-IDG -1.86113 81.7 133
Syntaxin-1B STX1B Tbio Non-IDG -1.73730 52.6 27
BET1 homolog BET1 Tdark Non-IDG -2.15809 136.2 3
Syntaxin-6 STX6 Tbio Non-IDG -1.75231 53.1 215
Synaptobrevin homolog YKT6 YKT6 Tbio Non-IDG -1.55865 36.8 21
Syntaxin-8 STX8 Tbio Non-IDG -2.56822 375.2 113