Development Level

Tbio 57 | 11,445
Tdark 18 | 6,588
Tchem 3 | 1,598

Collection

Kinase: IDG Consortium (Target... 3 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to o... 3 | 239
abnormal coat-hair pigmentatio... 1 | 64
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
decreased circulating chloride... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased vertical activity 1 | 208
enlarged heart 1 | 210
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 96
increased mean platelet volume 1 | 45
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 52 | 11,493
ovarian cancer 45 | 8,520
lung cancer 28 | 4,740
osteosarcoma 28 | 7,950
group 3 medulloblastoma 21 | 4,104
medulloblastoma, large-cell 19 | 6,241
acute quadriplegic myopathy 16 | 1,158
psoriasis 16 | 6,694
colon cancer 15 | 1,478
glioblastoma 15 | 5,792
Multiple myeloma 12 | 1,332
atypical teratoid / rhabdoid tumor 12 | 5,112
malignant mesothelioma 11 | 3,232
Kidney cancer 10 | 2,613
Waldenstrons macroglobulinemia 10 | 765
Cancer 9 | 2,499
Intellectual disability 9 | 1,016
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
non-small cell lung cancer 9 | 2,890
primitive neuroectodermal tumor 9 | 3,035
invasive ductal carcinoma 8 | 2,951
non primary Sjogren syndrome sicca 8 | 891
Breast cancer 7 | 3,578
dermatomyositis 7 | 966
diabetes mellitus 7 | 1,728
ependymoma 7 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
Autosomal recessive predisposition 6 | 1,442
Short stature 6 | 531
oligodendroglioma 6 | 2,850
pediatric high grade glioma 6 | 1,064
Adenocarcinoma of lung 5 | 142
Disease Models, Animal 5 | 155
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Osteoporosis 5 | 363
Poor school performance 5 | 645
Small head 5 | 374
adult high grade glioma 5 | 3,801
juvenile dermatomyositis 5 | 1,187
spina bifida 5 | 1,074
Anemia 4 | 365
Bowen-Conradi syndrome 4 | 16
Cognitive delay 4 | 608
Decreased platelet count 4 | 111
Dental caries 4 | 164
Dyskeratosis congenita 4 | 24
Global developmental delay 4 | 608
Hemoglobin low 4 | 124
Hyperpigmentation 4 | 37
Hypodontia 4 | 81
Liver Cirrhosis 4 | 181
Malabsorption 4 | 82
Mental and motor retardation 4 | 608
Pick disease 4 | 1,894
Rotting teeth 4 | 73
Shwachman-Diamond syndrome 4 | 17
Skin Ulcer 4 | 48
Squamous cell carcinoma 4 | 129
Thrombocytopenia 4 | 197
acute myeloid leukemia 4 | 783
astrocytic glioma 4 | 2,597
lung adenocarcinoma 4 | 2,716
medulloblastoma 4 | 720
pancreatic cancer 4 | 2,398
sonic hedgehog group medulloblastoma 4 | 467
tuberculosis 4 | 2,010
Abnormal blistering of the skin 3 | 54
Astrocytoma, Pilocytic 3 | 3,081
Blood Coagulation Disorders 3 | 42
Cellular immunodeficiency 3 | 17
Coagulation abnormalities 3 | 27
Dystrophia unguium 3 | 53
Frequent fractures 3 | 53
HIV Infections 3 | 102
Hemorrhagic Disorders 3 | 30
Hyperhidrosis disorder 3 | 81
Increased fracture rate 3 | 53
Increased sweating 3 | 81
Liver cancer 3 | 604
Male infertility 3 | 206
Neutrophil abnormality 3 | 20
Pancytopenia 3 | 45
Recurrent respiratory infections 3 | 141
Schizophrenia 3 | 1,160
Skin bulla 3 | 54
Sparse hair 3 | 59
Sweating 3 | 81
Thin, sparse hair 3 | 59
Varying degree of multiple fractures 3 | 53
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
gastric carcinoma 3 | 807
hepatocellular carcinoma 3 | 547
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
posterior fossa group B ependymoma 3 | 416
subependymal giant cell astrocytoma 3 | 2,287

Tissue

Male tissues 76 | 17,142
Digestive Tract 75 | 17,369
Endocrine System 75 | 18,159
Female tissues 75 | 17,400
Nervous System 75 | 16,725
Respiratory system 75 | 16,393
Blood and immune system 74 | 16,909
Skin and soft tissues 74 | 17,230
Urinary Tract 74 | 16,678
Cardiovascular System 73 | 15,192
Liver and Pancreas 73 | 16,750

Target Family

Non-IDG 48 | 12,091
Enzyme 23 | 4,145
Kinase 7 | 634

KEGG Pathway

Ribosome biogenesis in eukaryo... 78 | 78
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NTF2-related export protein 1 NXT1 Tbio Non-IDG -1.49831 29.4 91
U3 small nucleolar RNA-associated protein 18 homolog UTP18 Tdark Non-IDG -0.50488 2.92 52
Guanine nucleotide-binding protein-like 3-like protein GNL3L Tbio Non-IDG -0.65739 5.74 141
Serine/threonine-protein kinase RIO1 RIOK1 Tchem Kinase -0.83569 7.38 159
Oligoribonuclease, mitochondrial REXO2 Tbio Enzyme -2.15502 143.8 115
Treacle protein TCOF1 Tbio Non-IDG -3.44117 2743.5 131
Adenylate kinase isoenzyme 6 AK6 Tbio Kinase -2.18859 223.1 91
Midasin MDN1 Tdark Non-IDG -1.23175 16.3 10
Ribosome maturation protein SBDS SBDS Tbio Non-IDG -2.24233 174.4 139
Nucleolar protein 58 NOP58 Tbio Non-IDG -1.46442 30.0 85