Development Level

Tbio 64 | 11,445
Tchem 18 | 1,598
Tclin 15 | 613
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to t... 8 | 278
embryonic lethality prior to o... 7 | 239
small superior vagus ganglion 3 | 74
abnormal behavior 2 | 298
abnormal seminal vesicle morph... 2 | 114
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
enlarged heart 2 | 210
enlarged uterus 2 | 11
increased bone mineral content 2 | 108
increased neutrophil cell numb... 2 | 46
short tibia 2 | 97
abnormal cecum morphology 1 | 7
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal pericardium morpholog... 1 | 26
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased CD4-positive, alpha ... 1 | 4
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased heart rate variabili... 1 | 7
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
limb grasping 1 | 41
small adrenal glands 1 | 16
small lymph nodes 1 | 1
syndactyly 1 | 23
thrombocytosis 1 | 27

Disease

psoriasis 50 | 6,694
lung carcinoma 45 | 2,843
ovarian cancer 45 | 8,520
Cancer 44 | 2,499
Rheumatoid arthritis 42 | 1,191
diabetes mellitus 41 | 1,728
lung cancer 41 | 4,740
tuberculosis 41 | 2,010
glioblastoma 40 | 5,792
Carcinoma 39 | 11,493
ulcerative colitis 35 | 1,819
interstitial cystitis 34 | 2,312
osteosarcoma 34 | 7,950
cystic fibrosis 33 | 1,696
Multiple Sclerosis 32 | 540
Arthritis 31 | 290
malignant mesothelioma 31 | 3,232
invasive ductal carcinoma 30 | 2,951
non-small cell lung cancer 30 | 2,890
adult high grade glioma 29 | 3,801
Hypersensitivity reaction type II disease 28 | 253
ependymoma 28 | 4,679
Asthma 27 | 385
Astrocytoma, Pilocytic 27 | 3,081
medulloblastoma, large-cell 26 | 6,241
sarcoidosis 26 | 370
Breast cancer 25 | 3,578
periodontitis 25 | 293
Schizophrenia 24 | 1,160
Dermatitis 23 | 157
Inflammatory bowel disease 23 | 151
atypical teratoid / rhabdoid tumor 23 | 5,112
Atherosclerosis 21 | 291
Kidney disease 21 | 430
cutaneous lupus erythematosus 21 | 1,057
pancreatic cancer 21 | 2,398
Coronary artery disease 20 | 268
Liver Cirrhosis, Experimental 20 | 769
Berylliosis 19 | 28
Lung disease 19 | 142
Hypersensitivity 18 | 63
Liver disease 18 | 237
Narcolepsy 18 | 72
Systemic lupus erythematosus 18 | 194
subependymal giant cell astrocytoma 18 | 2,287
Bipolar Disorder 17 | 666
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
Arthritis, Rheumatoid 16 | 174
Inflammation 16 | 120
Pneumonia 16 | 174
Vasculitis 16 | 80
breast carcinoma 16 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
lung adenocarcinoma 16 | 2,716
Allergic hypersensitivity disease 15 | 126
Endometriosis 15 | 540
Hypertension 15 | 396
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
primary Sjogren syndrome 15 | 735
Breast Neoplasms 14 | 445
Cerebrovascular disease 14 | 238
Chemical and Drug Induced Liver Injury 14 | 195
Heart disease 14 | 306
Human immunodeficiency virus infectious disease 14 | 138
Influenza 14 | 142
Mammary Neoplasms 14 | 425
Multiple Sclerosis, Susceptibility to 14 | 15
Narcolepsy-cataplexy 14 | 21
Obesity 14 | 678
Pulmonary Fibrosis 14 | 106
Rheumatoid Arthritis, Systemic Juvenile 14 | 16
active Crohn's disease 14 | 922
colon cancer 14 | 1,478
Diffuse cutaneous systemic sclerosis 13 | 17
Hepatitis B 13 | 108
Reperfusion Injury 13 | 86
Sarcoidosis 1 13 | 14
astrocytic glioma 13 | 2,597
follicular lymphoma 13 | 20
limited scleroderma 13 | 19
Anemia 12 | 365
Brain Ischemia 12 | 110
Leishmaniasis 12 | 47
Malaria 12 | 160
Osteoporosis 12 | 363
Synovitis 12 | 78
oligodendroglioma 12 | 2,850
pituitary cancer 12 | 1,972
Alzheimer's disease 11 | 658
Collagen disease 11 | 27
Hypereosinophilic syndrome 11 | 71
Hypertensive disease 11 | 292
Juvenile rheumatoid arthritis 11 | 111
Mental Depression 11 | 333
Multiple myeloma 11 | 1,332
Osteopetrosis 11 | 43
adrenocortical carcinoma 11 | 1,428
astrocytoma 11 | 1,146
hepatocellular carcinoma 11 | 547
Duchenne muscular dystrophy 10 | 601

Tissue

Blood and immune system 85 | 16,909
Male tissues 84 | 17,142
Skin and soft tissues 84 | 17,230
Urinary Tract 84 | 16,678
Digestive Tract 83 | 17,369
Liver and Pancreas 83 | 16,750
Respiratory system 83 | 16,393
Endocrine System 82 | 18,159
Female tissues 82 | 17,400
Nervous System 76 | 16,725
Cardiovascular System 70 | 15,192

Target Family

Non-IDG 68 | 12,091
Enzyme 28 | 4,145
Kinase 2 | 634
Transcription Factor 2 | 1,400

KEGG Pathway

Rheumatoid arthritis 100 | 100
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor necrosis factor receptor superfamily member 11A TNFRSF11A Tbio Non-IDG -3.26478 1689.0 464
C-C motif chemokine 3-like 1 CCL3L1 Tbio Non-IDG -1.80717 51.3 142
V-type proton ATPase 116 kDa subunit a isoform 4 ATP6V0A4 Tbio Enzyme -2.84949 692.2 90
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
HLA class II histocompatibility antigen, DRB1-9 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 0
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
HLA class II histocompatibility antigen, DRB1-14 beta chain HLA-DRB1 Tbio Non-IDG 0.00000 489
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
V-type proton ATPase subunit E 1 ATP6V1E1 Tbio Enzyme -1.04091 10.7 137
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.83801 66.4 144