Development Level

Tclin 24 | 602
Tbio 20 | 10,625
Tchem 20 | 1,890
Tdark 2 | 7,003

Collection

Eligible Ion Channel Proteins 4 | 117
Eligible Kinase Proteins 2 | 134

IMPC Term

abnormal bone mineralization 4 | 55
abnormal bone structure 4 | 131
increased heart weight 4 | 37
abnormal behavior 3 | 226
abnormal embryo size 2 | 112
abnormal spleen morphology 2 | 36
hypoactivity 2 | 89
increased circulating alkaline... 2 | 119
male infertility 2 | 62
preweaning lethality, complete... 2 | 633
abnormal facial morphology 1 | 9
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placenta vasculature 1 | 2
abnormal vocalization 1 | 21
cyanosis 1 | 6
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating bilirubi... 1 | 14
decreased circulating insulin ... 1 | 75
decreased circulating magnesiu... 1 | 11
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
edema 1 | 11
embryonic lethality prior to t... 1 | 187
enlarged spleen 1 | 26
hemorrhage 1 | 12
impaired glucose tolerance 1 | 52
increased bone mineral content 1 | 92
increased circulating total pr... 1 | 20
prenatal lethality 1 | 16
preweaning lethality, incomple... 1 | 260
respiratory system phenotype 1 | 2
small epididymis 1 | 3

Disease

psoriasis 33 | 6,685
ovarian cancer 32 | 8,484
medulloblastoma, large-cell 31 | 6,234
glioblastoma 30 | 5,572
osteosarcoma 28 | 7,933
lung cancer 26 | 4,466
atypical teratoid / rhabdoid tumor 25 | 4,369
Breast cancer 22 | 3,094
pilocytic astrocytoma 22 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
invasive ductal carcinoma 20 | 2,950
lung adenocarcinoma 20 | 2,713
malignant mesothelioma 20 | 3,162
primitive neuroectodermal tumor 20 | 3,031
colon cancer 19 | 1,475
lung carcinoma 19 | 2,844
oligodendroglioma 19 | 2,849
pancreatic cancer 19 | 2,300
interstitial cystitis 18 | 2,299
Cancer 17 | 2,346
Carcinoma 17 | 2,147
Obesity 17 | 616
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
non-small cell lung cancer 17 | 2,798
ulcerative colitis 17 | 2,087
Pick disease 16 | 1,893
adult high grade glioma 16 | 2,148
astrocytic glioma 16 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
subependymal giant cell astrocytoma 15 | 2,287
ductal carcinoma in situ 14 | 1,745
ependymoma 14 | 2,514
Hypertensive disease 13 | 193
cystic fibrosis 13 | 1,665
Atrial Fibrillation 12 | 110
Chronic heart failure 12 | 46
Hypertensive disorder 12 | 58
diabetes mellitus 12 | 1,663
pediatric high grade glioma 12 | 2,712
posterior fossa group A ependymoma 12 | 1,511
Hypertension 11 | 287
Kidney disease 10 | 396
breast carcinoma 10 | 1,614
medulloblastoma 10 | 1,524
pituitary cancer 10 | 1,972
Angina pectoris 9 | 21
Heart disease 9 | 279
Parkinson's disease 9 | 364
group 3 medulloblastoma 9 | 2,254
group 4 medulloblastoma 9 | 1,875
primary pancreatic ductal adenocarcinoma 9 | 1,271
sonic hedgehog group medulloblastoma 9 | 1,482
Rheumatoid Arthritis 8 | 1,160
astrocytoma 8 | 1,493
cutaneous lupus erythematosus 8 | 1,056
gastric carcinoma 8 | 832
Asthma 7 | 349
Cerebrovascular disease 7 | 231
Coronary artery disease 7 | 240
Decompensated cardiac failure 7 | 9
Heart failure 7 | 80
Left ventricular cardiac dysfunction 7 | 9
Myocardial Infarction 7 | 126
Schizophrenia 7 | 501
esophageal adenocarcinoma 7 | 737
posterior fossa group B ependymoma 7 | 1,530
Adenoma 6 | 165
Carney complex 6 | 23
Cushing's syndrome 6 | 47
Endometriosis 6 | 535
Epilepsy 6 | 346
Hyperthyroidism 6 | 50
Hypokalemia 6 | 40
Impotence 6 | 45
Left Ventricular Hypertrophy 6 | 24
Myocardial Perfusion Imaging Adjunct 6 | 25
Prostatic Neoplasms 6 | 471
progressive supranuclear palsy 6 | 674
tuberculosis 6 | 1,557
Alzheimer's disease 5 | 644
Brachydactyly 5 | 52
Down syndrome 5 | 548
Fibrosis 5 | 40
Hypothyroidism 5 | 89
Kidney Diseases 5 | 86
Kidney cancer 5 | 118
Metabolic syndrome X 5 | 155
Platelet Aggregation Inhibition 5 | 22
Pulmonary hypertension 5 | 52
Substance Withdrawal Syndrome 5 | 52
Vascular disease 5 | 281
Waldenstrons macroglobulinemia 5 | 765
acute myeloid leukemia 5 | 780
acute quadriplegic myopathy 5 | 1,157
atypical teratoid/rhabdoid tumor 5 | 1,095
juvenile dermatomyositis 5 | 1,189
nasopharyngeal carcinoma 5 | 1,056
pancreatic carcinoma 5 | 567
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
sarcoidosis 5 | 358

Tissue

Blood and immune system 65 | 17,995
Cardiovascular System 65 | 17,958
Female tissues 65 | 18,647
Liver and Pancreas 65 | 18,136
Male tissues 65 | 17,969
Nervous System 65 | 18,561
Digestive Tract 64 | 18,473
Endocrine System 64 | 18,512
Respiratory system 64 | 17,484
Urinary Tract 64 | 18,444
Skin and soft tissues 62 | 18,115

Target Family

Enzyme 21 | 4,146
Non-IDG 17 | 11,971
Ion Channel 13 | 341
GPCR 9 | 406
Kinase 5 | 634
Transcription Factor 1 | 1,400

KEGG Pathway

Renin secretion 66 | 66
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-3 adrenergic receptor ADRB3 Tclin GPCR -2.70027 550.2 236
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA Tchem Enzyme -2.95943 932.4 290
Guanine nucleotide-binding protein G(i) subunit alpha-2 GNAI2 Tbio Non-IDG -1.23038 16.6 188
Calcium-activated chloride channel regulator 2 CLCA2 Tchem Ion Channel -1.98878 90.3 50
Calmodulin CALM3 Tclin Non-IDG -3.77570 5075.9 259
Aquaporin-1 AQP1 Tbio Non-IDG -3.04203 1040.5 321
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.70830 492.8 177
Angiotensinogen AGT Tchem Non-IDG -3.23051 1673.4 609
Inward rectifier potassium channel 2 KCNJ2 Tchem Ion Channel -2.32321 207.3 201
Endothelin-1 receptor EDNRA Tclin GPCR -2.82627 617.3 245