Development Level

Tbio 27 | 11,445
Tclin 26 | 613
Tchem 13 | 1,598
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal bone structure 4 | 187
abnormal embryo size 4 | 220
increased heart weight 4 | 62
increased startle reflex 4 | 112
preweaning lethality, complete... 4 | 979
abnormal behavior 2 | 298
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
hydrometra 2 | 53
hypoactivity 2 | 132
increased bone mineral content 2 | 108
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
prolonged ST segment 2 | 36
small superior vagus ganglion 2 | 74
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal gallbladder morpholog... 1 | 1
abnormal locomotor behavior 1 | 24
abnormal placenta vasculature 1 | 2
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
cyanosis 1 | 7
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged gallbladder 1 | 2
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
respiratory system phenotype 1 | 2
small epididymis 1 | 3

Disease

Carcinoma 55 | 11,493
ovarian cancer 36 | 8,520
psoriasis 34 | 6,694
glioblastoma 32 | 5,792
medulloblastoma, large-cell 32 | 6,241
ependymoma 31 | 4,679
lung cancer 30 | 4,740
atypical teratoid / rhabdoid tumor 29 | 5,112
osteosarcoma 29 | 7,950
Breast cancer 26 | 3,578
adult high grade glioma 25 | 3,801
group 3 medulloblastoma 24 | 4,104
Astrocytoma, Pilocytic 23 | 3,081
Kidney cancer 22 | 2,613
astrocytic glioma 21 | 2,597
primitive neuroectodermal tumor 21 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
invasive ductal carcinoma 20 | 2,951
lung adenocarcinoma 20 | 2,716
malignant mesothelioma 20 | 3,232
oligodendroglioma 20 | 2,850
pancreatic cancer 20 | 2,398
Cancer 19 | 2,499
Hypertension 19 | 396
colon cancer 19 | 1,478
lung carcinoma 19 | 2,843
non-small cell lung cancer 19 | 2,890
Obesity 18 | 678
interstitial cystitis 18 | 2,312
Pick disease 17 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
ulcerative colitis 17 | 1,819
Hypertensive disease 16 | 292
Schizophrenia 16 | 1,160
diabetes mellitus 16 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
subependymal giant cell astrocytoma 16 | 2,287
Depressive disorder 14 | 409
ductal carcinoma in situ 14 | 1,745
Heart disease 13 | 306
cystic fibrosis 13 | 1,696
Autosomal recessive predisposition 12 | 1,442
Bipolar Disorder 12 | 666
Chronic heart failure 12 | 46
Hypertensive disorder 12 | 56
Mental Depression 11 | 333
Atrial Fibrillation 10 | 124
Epilepsy 10 | 792
Kidney disease 10 | 430
breast carcinoma 10 | 1,638
pituitary cancer 10 | 1,972
Angina Pectoris 9 | 32
Cerebrovascular disease 9 | 238
Liver cancer 9 | 604
Parkinson's disease 9 | 392
group 4 medulloblastoma 9 | 1,855
tuberculosis 9 | 2,010
Heart failure 8 | 162
Left Ventricular Hypertrophy 8 | 47
Rheumatoid arthritis 8 | 1,191
Substance Withdrawal Syndrome 8 | 55
cutaneous lupus erythematosus 8 | 1,057
gastric carcinoma 8 | 807
primary pancreatic ductal adenocarcinoma 8 | 1,109
Alzheimer's disease 7 | 658
Asthma 7 | 385
Coronary artery disease 7 | 268
Decompensated cardiac failure 7 | 9
Left ventricular cardiac dysfunction 7 | 9
Major Depressive Disorder 7 | 301
Melanoma 7 | 711
Myocardial Infarction 7 | 151
Unipolar Depression 7 | 250
esophageal adenocarcinoma 7 | 737
Adenoma 6 | 167
Brachydactyly 6 | 156
Carney complex 6 | 25
Cerebrovascular accident 6 | 63
Cushing's syndrome 6 | 48
Endometriosis 6 | 540
Hyperthyroidism 6 | 53
Hypertrophy, Left Ventricular 6 | 24
Hypokalemia 6 | 52
Impotence 6 | 42
Myocardial Perfusion Imaging Adjunct 6 | 25
Osteoporosis 6 | 363
Prostatic Neoplasms 6 | 495
Pulmonary hypertension 6 | 85
Skin cancer 6 | 469
Vascular disease 6 | 319
Ventricular arrhythmia 6 | 27
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
progressive supranuclear palsy 6 | 676
Down syndrome 5 | 499
Glaucoma 5 | 239
acute myeloid leukemia 5 | 783
acute quadriplegic myopathy 5 | 1,158
juvenile dermatomyositis 5 | 1,187
nasopharyngeal carcinoma 5 | 1,058
pancreatic carcinoma 5 | 562

Tissue

Endocrine System 65 | 18,159
Male tissues 64 | 17,142
Blood and immune system 63 | 16,909
Digestive Tract 63 | 17,369
Female tissues 63 | 17,400
Skin and soft tissues 63 | 17,230
Liver and Pancreas 62 | 16,750
Nervous System 62 | 16,725
Urinary Tract 61 | 16,678
Respiratory system 60 | 16,393
Cardiovascular System 56 | 15,192

Target Family

Enzyme 21 | 4,145
Non-IDG 19 | 12,091
Ion Channel 13 | 344
GPCR 9 | 408
Kinase 5 | 634
Transcription Factor 1 | 1,400

KEGG Pathway

Renin secretion 68 | 68
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aquaporin-1 AQP1 Tbio Non-IDG -3.08125 1107.4 374
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform PPP3CB Tbio Enzyme -1.53531 28.2 147
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A Tclin Enzyme -1.27429 21.3 169
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Inward rectifier potassium channel 2 KCNJ2 Tchem Ion Channel -2.36978 224.8 221
Adenylate cyclase type 6 ADCY6 Tchem Enzyme -2.05332 113.7 111
Calmodulin-like protein 5 CALML5 Tbio Non-IDG -1.32968 24.4 111
Calcineurin subunit B type 1 PPP3R1 Tbio Non-IDG -2.60752 391.4 125
Beta-3 adrenergic receptor ADRB3 Tclin GPCR -2.73090 568.4 254
Calcium-activated potassium channel subunit alpha-1 KCNMA1 Tclin Ion Channel -3.09649 1238.5 222