Development Level

Tchem 39 | 1,890
Tbio 20 | 10,625
Tclin 7 | 602

Collection

Kinase: IDG Consortium (Targets) 3 | 125

IMPC Phenotype

decreased body weight 3 | 174
preweaning lethality, complete... 3 | 633
decreased circulating creatini... 2 | 31
decreased lean body mass 2 | 195
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal gait 1 | 51
abnormal glucose homeostasis 1 | 5
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal respiratory quotient 1 | 9
abnormal retinal pigmentation 1 | 61
cataract 1 | 26
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 37
decreased circulating alanine ... 1 | 53
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased total body fat amoun... 1 | 186
hydrops fetalis 1 | 22
increased blood urea nitrogen ... 1 | 44
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
prenatal lethality prior to he... 1 | 64
thrombocytosis 1 | 23

Disease

ovarian cancer 50 | 8,491
Cancer 49 | 2,346
osteosarcoma 39 | 7,933
medulloblastoma, large-cell 30 | 6,234
atypical teratoid / rhabdoid tumor 28 | 4,369
glioblastoma 28 | 5,572
lung cancer 26 | 4,473
psoriasis 26 | 6,685
Breast cancer 25 | 3,098
Carcinoma 22 | 2,147
ependymoma 20 | 2,514
oligodendroglioma 20 | 2,849
astrocytic glioma 18 | 2,241
invasive ductal carcinoma 17 | 2,950
non-small cell lung cancer 17 | 2,798
pancreatic cancer 17 | 2,300
pilocytic astrocytoma 17 | 3,086
pediatric high grade glioma 16 | 2,712
ulcerative colitis 16 | 2,087
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
malignant mesothelioma 15 | 3,163
medulloblastoma 14 | 1,524
subependymal giant cell astrocytoma 14 | 2,287
diabetes mellitus 13 | 1,663
juvenile dermatomyositis 13 | 1,189
lung carcinoma 13 | 2,844
Lung Neoplasms 12 | 171
Mammary Neoplasms 12 | 410
Multiple myeloma 12 | 1,327
Renal Cell Carcinoma 12 | 199
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,956
lung adenocarcinoma 12 | 2,714
Intellectual disability 11 | 573
Liver carcinoma 11 | 217
Noonan Syndrome 11 | 33
group 4 medulloblastoma 11 | 1,875
primitive neuroectodermal tumor 11 | 3,031
Prostatic Neoplasms 10 | 471
Schizophrenia 10 | 503
Squamous cell carcinoma 10 | 96
cystic fibrosis 10 | 1,670
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
non-small cell lung carcinoma 10 | 413
Colorectal Neoplasms 9 | 217
Kidney cancer 9 | 121
Obesity 9 | 616
Pick disease 9 | 1,893
Rheumatoid Arthritis 9 | 1,170
Vascular disease 9 | 281
adult high grade glioma 9 | 2,148
astrocytoma 9 | 1,493
breast carcinoma 9 | 1,614
dermatomyositis 9 | 966
Adenoma 8 | 165
Kidney disease 8 | 397
Liver neoplasms 8 | 108
Stomach Neoplasms 8 | 282
acute myeloid leukemia 8 | 785
ductal carcinoma in situ 8 | 1,745
interstitial cystitis 8 | 2,299
pancreatic carcinoma 8 | 567
pituitary cancer 8 | 1,972
primary pancreatic ductal adenocarcinoma 8 | 1,271
tuberculosis 8 | 1,563
Cardiofaciocutaneous syndrome 7 | 15
Costello Syndrome 7 | 18
Heart disease 7 | 279
Hemangioma 7 | 35
LEOPARD Syndrome 7 | 20
Liver Cirrhosis 7 | 101
Melanoma 7 | 261
Neoplasm Invasiveness 7 | 127
Neoplasm Metastasis 7 | 138
Parkinson's disease 7 | 364
Waldenstrons macroglobulinemia 7 | 764
group 3 medulloblastoma 7 | 2,254
ovarian neoplasm 7 | 97
Alzheimer's disease 6 | 644
Arthritis 6 | 248
Cardio-facio-cutaneous syndrome 6 | 6
Cardiomyopathy 6 | 110
Colon Carcinoma 6 | 25
Costello syndrome (disorder) 6 | 7
Endometriosis 6 | 535
Liver disease 6 | 219
Neoplasms, Experimental 6 | 33
Neoplastic Cell Transformation 6 | 81
Neuroblastoma 6 | 78
acute quadriplegic myopathy 6 | 1,157
adrenocortical carcinoma 6 | 1,427
colon cancer 6 | 1,475
hepatocellular carcinoma 6 | 550
nasopharyngeal carcinoma 6 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
posterior fossa group A ependymoma 6 | 1,511
tuberculosis and treatment for 6 months 6 | 686
Asthma 5 | 349
Brain Ischemia 5 | 87
gastric carcinoma 5 | 832
spina bifida 5 | 1,064

Tissue

Blood and immune system 66 | 17,994
Cardiovascular System 66 | 17,957
Digestive Tract 66 | 18,472
Endocrine System 66 | 18,511
Female tissues 66 | 18,646
Liver and Pancreas 66 | 18,135
Male tissues 66 | 17,968
Nervous System 66 | 18,560
Respiratory system 66 | 17,483
Skin and soft tissues 66 | 18,114
Urinary Tract 66 | 18,443

Target Family

Kinase 22 | 634
Non-IDG 21 | 11,969
Enzyme 15 | 4,146
Transcription Factor 5 | 1,400
Epigenetic 2 | 242
Transporter 1 | 473

KEGG Pathway

Renal cell carcinoma 66 | 66
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Von Hippel-Lindau disease tumor suppressor VHL Tchem Enzyme -2.45725 283.9 450
Serine/threonine-protein kinase B-raf BRAF Tclin Kinase -2.28702 199.1 1276
GTPase KRas KRAS Tbio Enzyme -3.77389 5694.2 421
Protransforming growth factor alpha TGFA Tbio Non-IDG -2.13802 123.3 575
Aryl hydrocarbon receptor nuclear translocator ARNT Tbio Transcription Factor -2.51053 243.3 424
Hepatocyte growth factor HGF Tchem Enzyme -3.29371 2317.3 573
GTPase HRas HRAS Tchem Enzyme -3.99319 9497.9 312
GTPase NRas NRAS Tchem Enzyme -2.98048 880.4 265
Platelet-derived growth factor subunit B PDGFB Tchem Non-IDG -3.24522 1684.0 357
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.87449 73.5 395