Development Level

Tbio 27 | 11,445
Tchem 17 | 1,598
Tclin 13 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

increased heart weight 5 | 62
abnormal bone structure 4 | 187
increased startle reflex 4 | 112
decreased body weight 3 | 161
preweaning lethality, incomple... 3 | 499
decreased circulating creatini... 2 | 39
decreased vertical activity 2 | 208
enlarged heart 2 | 210
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal duodenum morphology 1 | 4
abnormal glucose homeostasis 1 | 4
abnormal heart morphology 1 | 162
abnormal maxilla morphology 1 | 17
abnormal spleen morphology 1 | 55
decreased circulating LDL chol... 1 | 38
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased total body fat amoun... 1 | 207
enlarged spleen 1 | 41
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
male infertility 1 | 123
thrombocytosis 1 | 27

Disease

Carcinoma 48 | 11,493
ovarian cancer 35 | 8,520
psoriasis 33 | 6,694
medulloblastoma, large-cell 27 | 6,241
osteosarcoma 27 | 7,950
lung cancer 26 | 4,740
Obesity 25 | 678
atypical teratoid / rhabdoid tumor 25 | 5,112
invasive ductal carcinoma 24 | 2,951
glioblastoma 23 | 5,792
Cancer 20 | 2,499
ependymoma 20 | 4,679
Kidney cancer 19 | 2,613
diabetes mellitus 19 | 1,728
group 3 medulloblastoma 19 | 4,104
adult high grade glioma 18 | 3,801
ductal carcinoma in situ 18 | 1,745
lung carcinoma 18 | 2,843
Breast cancer 17 | 3,578
breast carcinoma 17 | 1,638
pancreatic cancer 16 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
primitive neuroectodermal tumor 15 | 3,035
Polycystic ovary syndrome 14 | 360
Schizophrenia 14 | 1,160
astrocytic glioma 14 | 2,597
lung adenocarcinoma 14 | 2,716
interstitial cystitis 13 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
non-small cell lung cancer 13 | 2,890
Astrocytoma, Pilocytic 12 | 3,081
Hypertension 12 | 396
malignant mesothelioma 12 | 3,232
oligodendroglioma 12 | 2,850
pituitary cancer 12 | 1,972
ulcerative colitis 12 | 1,819
Autosomal recessive predisposition 11 | 1,442
Depressive disorder 11 | 409
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Adenoma 10 | 167
Epilepsy 10 | 792
Hypothyroidism 10 | 122
colon cancer 10 | 1,478
Asthma 9 | 385
Bipolar Disorder 9 | 666
Hypertensive disease 9 | 292
Hyperthyroidism 9 | 53
Insulin Resistance 9 | 72
Seizures 9 | 596
Substance Withdrawal Syndrome 9 | 55
subependymal giant cell astrocytoma 9 | 2,287
Alzheimer's disease 8 | 658
Hyperglycemia 8 | 137
Mental Depression 8 | 333
Mood Disorders 8 | 184
Prostatic Neoplasms 8 | 495
adrenocortical carcinoma 8 | 1,428
cystic fibrosis 8 | 1,696
fibroadenoma 8 | 559
Atopic dermatitis 7 | 952
Concave bridge of nose 7 | 195
Coronary artery disease 7 | 268
Depressed nasal bridge 7 | 195
Depressed nasal root/bridge 7 | 195
Fatty liver disease 7 | 103
Heart disease 7 | 306
Hyperinsulinism 7 | 133
Kidney disease 7 | 430
Liver cancer 7 | 604
Osteoporosis 7 | 363
Parkinson's disease 7 | 392
Thyroid cancer 7 | 36
medulloblastoma 7 | 720
Acquired metabolic disease 6 | 336
Acromegaly 6 | 51
Breast Neoplasms 6 | 445
Carney complex 6 | 25
Cataract 6 | 297
Cognitive delay 6 | 608
Cushing's syndrome 6 | 48
Diabetes Mellitus, Non-Insulin-Dependent 6 | 145
Dull intelligence 6 | 645
Fatigue 6 | 182
Global developmental delay 6 | 608
Heart failure 6 | 162
Intellectual disability 6 | 1,016
Low intelligence 6 | 645
Mammary Neoplasms 6 | 425
Mental Retardation 6 | 645
Mental and motor retardation 6 | 608
Mental deficiency 6 | 645
Pituitary adenoma 6 | 38
Poor school performance 6 | 645
Rheumatoid arthritis 6 | 1,191
Stomach Neoplasms 6 | 300
Unipolar Depression 6 | 250
astrocytoma 6 | 1,146
cutaneous lupus erythematosus 6 | 1,057
group 4 medulloblastoma 6 | 1,855
juvenile dermatomyositis 6 | 1,187

Tissue

Endocrine System 54 | 18,159
Digestive Tract 53 | 17,369
Female tissues 53 | 17,400
Nervous System 53 | 16,725
Skin and soft tissues 53 | 17,230
Blood and immune system 52 | 16,909
Liver and Pancreas 52 | 16,750
Male tissues 52 | 17,142
Urinary Tract 52 | 16,678
Respiratory system 51 | 16,393
Cardiovascular System 49 | 15,192

Target Family

Enzyme 18 | 4,145
Non-IDG 18 | 12,091
Kinase 14 | 634
GPCR 7 | 408

KEGG Pathway

Regulation of lipolysis in adi... 57 | 57
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Fatty acid-binding protein, adipocyte FABP4 Tchem Non-IDG -2.73935 617.7 605
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Adenylate cyclase type 6 ADCY6 Tchem Enzyme -2.05332 113.7 111
Glycoprotein hormones alpha chain CGA Tbio Non-IDG -2.62079 405.6 915
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.23035 1641.3 479
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.61657 45.3 134
Pro-neuropeptide Y NPY Tbio Non-IDG -3.83401 7433.3 432
Beta-3 adrenergic receptor ADRB3 Tclin GPCR -2.73090 568.4 254
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731