Development Level

Tbio 57 | 10,625
Tdark 15 | 7,003
Tchem 4 | 1,890

IMPC Term

preweaning lethality, complete... 8 | 633
embryonic lethality prior to o... 4 | 148
preweaning lethality, incomple... 4 | 260
increased mean corpuscular hem... 3 | 93
abnormal lens morphology 2 | 73
decreased NK cell number 2 | 16
decreased grip strength 2 | 123
embryonic lethality prior to t... 2 | 187
increased grip strength 2 | 83
increased mean corpuscular vol... 2 | 91
abnormal behavior 1 | 226
abnormal clavicle morphology 1 | 5
abnormal coat/hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal embryo turning 1 | 15
abnormal heart morphology 1 | 51
abnormal retina morphology 1 | 100
abnormal rib morphology 1 | 28
abnormal spine curvature 1 | 7
aorta dilation 1 | 3
decreased CD4-positive, CD25-p... 1 | 24
decreased KLRG1-positive NK ce... 1 | 9
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased lumbar vertebrae num... 1 | 62
decreased rib number 1 | 59
decreased startle reflex 1 | 48
embryonic growth retardation 1 | 28
enlarged heart 1 | 111
increased CD5-positive gamma-d... 1 | 1
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased granulocyte number 1 | 8
increased or absent threshold ... 1 | 128
prenatal lethality prior to he... 1 | 64

Disease

ovarian cancer 47 | 8,484
osteosarcoma 45 | 7,933
lung cancer 21 | 4,466
medulloblastoma, large-cell 20 | 6,234
psoriasis 20 | 6,685
group 3 medulloblastoma 19 | 2,254
glioblastoma 18 | 5,572
ependymoma 17 | 2,514
oligodendroglioma 16 | 2,849
atypical teratoid / rhabdoid tumor 15 | 4,369
malignant mesothelioma 14 | 3,162
pancreatic cancer 14 | 2,300
primitive neuroectodermal tumor 14 | 3,031
acute quadriplegic myopathy 13 | 1,157
lung adenocarcinoma 12 | 2,713
Multiple myeloma 11 | 1,327
astrocytoma 11 | 1,493
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
astrocytic glioma 10 | 2,241
group 4 medulloblastoma 10 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
invasive ductal carcinoma 9 | 2,950
pituitary cancer 9 | 1,972
primary pancreatic ductal adenocarcinoma 9 | 1,271
sonic hedgehog group medulloblastoma 9 | 1,482
Cancer 8 | 2,346
acute myeloid leukemia 8 | 780
atypical teratoid/rhabdoid tumor 8 | 1,095
diabetes mellitus 8 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
Carcinoma 7 | 2,147
Pick disease 7 | 1,893
Waldenstrons macroglobulinemia 7 | 765
Breast cancer 6 | 3,094
Rheumatoid Arthritis 6 | 1,160
adrenocortical carcinoma 6 | 1,427
adult high grade glioma 6 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
juvenile dermatomyositis 6 | 1,189
non-small cell lung cancer 6 | 2,798
pediatric high grade glioma 6 | 2,712
spina bifida 6 | 1,064
subependymal giant cell astrocytoma 6 | 2,287
tuberculosis 6 | 1,557
colon cancer 5 | 1,475
dermatomyositis 5 | 933
medulloblastoma 5 | 1,524
pilocytic astrocytoma 5 | 3,086
Down syndrome 4 | 548
Duchenne muscular dystrophy 4 | 602
Liver carcinoma 4 | 217
tuberculosis and treatment for 6 months 4 | 686
Alzheimer's disease 3 | 644
Dyskeratosis congenita 3 | 24
Glycogen storage disease 3 | 37
Neurodegenerative disease 3 | 383
Renal Cell Carcinoma 3 | 199
Stomach Neoplasms 3 | 282
aldosterone-producing adenoma 3 | 664
breast carcinoma 3 | 1,614
ductal carcinoma in situ 3 | 1,745
lung carcinoma 3 | 2,844
non-small cell lung carcinoma 3 | 413
pancreatic carcinoma 3 | 567
Adenocarcinoma 2 | 115
Amyotrophic Lateral Sclerosis 2 | 431
Attention deficit hyperactivity disorder 2 | 156
Bladder Neoplasm 2 | 109
Candidiasis 2 | 48
Cardiac arrest 2 | 26
Chloracne 2 | 32
Endometriosis 2 | 535
HIV Infections 2 | 100
Juvenile arthritis 2 | 124
Male infertility 2 | 170
Mammary Neoplasms 2 | 410
Myocardial Ischemia 2 | 169
Myositis 2 | 24
Polycystic Ovary Syndrome 2 | 332
Pontocerebellar Hypoplasia Type 1 2 | 5
Pontocerebellar hypoplasia 2 | 29
Schizophrenia 2 | 501
Spinocerebellar ataxia type 2 2 | 19
Systemic scleroderma 2 | 66
Type 2 diabetes mellitus 2 | 189
X-linked cerebral adrenoleukodystrophy 2 | 115
chronic rhinosinusitis 2 | 512
gastric cancer 2 | 430
glioblastoma multiforme 2 | 347
hepatocellular carcinoma 2 | 532
hereditary spastic paraplegia 2 | 313
inflammatory breast cancer 2 | 404
interstitial lung disease 2 | 291
nasopharyngeal carcinoma 2 | 1,056
periodontitis 2 | 269
posterior fossa group A ependymoma 2 | 1,511
primary Sjogren syndrome 2 | 789
progressive supranuclear palsy 2 | 674
tuberculosis and treatment for 3 months 2 | 327
ulcerative colitis 2 | 2,087

Tissue

Blood and immune system 76 | 17,995
Cardiovascular System 76 | 17,958
Digestive Tract 76 | 18,473
Endocrine System 76 | 18,512
Female tissues 76 | 18,647
Liver and Pancreas 76 | 18,136
Nervous System 76 | 18,561
Urinary Tract 76 | 18,444
Male tissues 75 | 17,969
Respiratory system 75 | 17,484
Skin and soft tissues 75 | 18,115

Target Family

Non-IDG 48 | 11,971
Enzyme 24 | 4,146
Kinase 4 | 634

KEGG Pathway

RNA degradation 76 | 76
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
m7GpppN-mRNA hydrolase DCP2 Tbio Enzyme -1.89749 80.7 139
5'-3' exoribonuclease 1 XRN1 Tbio Enzyme -2.06818 114.2 45
CCR4-NOT transcription complex subunit 3 CNOT3 Tbio Non-IDG -2.75148 523.8 179
Protein Tob1 TOB1 Tbio Non-IDG -1.56387 42.5 170
mRNA-decapping enzyme 1B DCP1B Tdark Non-IDG -0.31186 1.45 90
Beta-enolase ENO3 Tbio Enzyme -2.37121 235.8 236
Polyadenylate-binding protein 1-like PABPC1L Tdark Non-IDG -1.19601 16.7 28
5'-3' exoribonuclease 2 XRN2 Tbio Enzyme -1.48143 31.3 110
Non-canonical poly(A) RNA polymerase PAPD5 PAPD5 Tdark Enzyme -0.66756 3.45 104
ATP-dependent 6-phosphofructokinase, platelet type PFKP Tbio Kinase -1.89344 74.7 268