Development Level

Tbio 41 | 11,651
Tchem 21 | 1,388
Tdark 4 | 6,593
Tclin 3 | 612

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased circulating sodium l... 2 | 22
embryonic lethality prior to t... 2 | 278
increased circulating free fat... 2 | 20
increased leukocyte cell numbe... 2 | 47
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal lens morphology 1 | 81
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal skin condition 1 | 6
abnormal startle reflex 1 | 15
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased fasted circulating g... 1 | 65
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
embryonic growth retardation 1 | 106
female infertility 1 | 60
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased lymphocyte cell numb... 1 | 32
increased thermal nociceptive ... 1 | 9
short tibia 1 | 97
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

Cancer 34 | 2,499
Carcinoma 33 | 11,493
psoriasis 32 | 6,694
ovarian cancer 30 | 8,520
glioblastoma 28 | 5,792
osteosarcoma 24 | 7,950
adult high grade glioma 20 | 3,801
atypical teratoid / rhabdoid tumor 20 | 5,112
lung cancer 20 | 4,740
medulloblastoma, large-cell 19 | 6,241
Astrocytoma, Pilocytic 17 | 3,081
ependymoma 16 | 4,679
Multiple Sclerosis 14 | 540
Influenza 13 | 142
juvenile dermatomyositis 12 | 1,187
Breast cancer 11 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
malignant mesothelioma 11 | 3,232
Arthritis 10 | 290
Melanoma 10 | 711
group 4 medulloblastoma 10 | 1,855
subependymal giant cell astrocytoma 10 | 2,287
Asthma 9 | 385
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
cystic fibrosis 9 | 1,696
dermatomyositis 9 | 966
group 3 medulloblastoma 9 | 4,104
tuberculosis 9 | 2,010
Hepatitis C 8 | 94
cutaneous lupus erythematosus 8 | 1,057
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
lung carcinoma 8 | 2,843
oligodendroglioma 8 | 2,850
primitive neuroectodermal tumor 8 | 3,035
Hepatitis 7 | 67
Inflammatory bowel disease 7 | 151
Kidney cancer 7 | 2,613
Lung disease 7 | 142
Microphthalmia with limb anomalies 7 | 40
Reperfusion Injury 7 | 86
Schizophrenia 7 | 1,160
Systemic lupus erythematosus 7 | 194
diabetes mellitus 7 | 1,728
lung adenocarcinoma 7 | 2,716
ulcerative colitis 7 | 1,819
Anemia 6 | 365
Autosomal recessive predisposition 6 | 1,442
Brain Ischemia 6 | 110
Hepatitis B 6 | 108
Hypersensitivity reaction type II disease 6 | 253
Immunologic Deficiency Syndromes 6 | 113
Liver Cirrhosis, Experimental 6 | 769
Liver carcinoma 6 | 240
Multiple myeloma 6 | 1,332
Rheumatoid arthritis 6 | 1,191
Vascular disease 6 | 319
Vasculitis 6 | 80
invasive ductal carcinoma 6 | 2,951
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
primary Sjogren syndrome 6 | 735
Carcinoma, Hepatocellular 5 | 228
Cholestasis 5 | 155
Cholestasis, Extrahepatic 5 | 25
Depressive disorder 5 | 409
Encephalitis 5 | 64
Epilepsy 5 | 792
Fever 5 | 138
Gaucher disease type 1 5 | 180
Influenza, Human 5 | 51
Kidney disease 5 | 430
Leukopenia 5 | 72
Neoplasms, Experimental 5 | 40
Osteoporosis 5 | 363
Pancreatic Neoplasm 5 | 85
Pancreatic Neoplasms 5 | 85
Pneumonia 5 | 174
Seizures 5 | 596
Severe acute respiratory syndrome 5 | 27
Stomach Neoplasms 5 | 300
active Crohn's disease 5 | 922
acute myeloid leukemia 5 | 783
acute quadriplegic myopathy 5 | 1,158
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Diabetes Mellitus, Type 2 4 | 142
Hypertension 4 | 396
Myocardial Ischemia 4 | 169
Pick disease 4 | 1,894
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
hepatocellular carcinoma 4 | 547
pituitary cancer 4 | 1,972

Tissue

Blood and immune system 58 | 16,909
Male tissues 56 | 17,142
Endocrine System 55 | 18,159
Nervous System 55 | 16,725
Skin and soft tissues 55 | 17,230
Urinary Tract 55 | 16,678
Digestive Tract 54 | 17,369
Female tissues 54 | 17,400
Liver and Pancreas 53 | 16,750
Respiratory system 53 | 16,393
Cardiovascular System 51 | 15,192

Target Family

Non-IDG 38 | 12,091
Kinase 15 | 634
Enzyme 12 | 4,145
Transcription Factor 4 | 1,400

KEGG Pathway

RIG-I-like receptor signaling ... 69 | 69
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
Stimulator of interferon genes protein TMEM173 Tbio Non-IDG -2.37722 230.3 450
Interferon epsilon IFNE Tbio Non-IDG -1.68928 47.2 109
NLR family member X1 NLRX1 Tbio Non-IDG -1.92925 86.9 143
TNF receptor-associated factor 6 TRAF6 Tbio Non-IDG -2.74221 511.1 403
Ubiquitin-like protein ATG12 ATG12 Tbio Non-IDG -2.17958 122.1 528
Mitogen-activated protein kinase kinase kinase 7 MAP3K7 Tchem Kinase -1.46817 32.4 765
Mitogen-activated protein kinase 12 MAPK12 Tchem Kinase -1.95173 88.4 378
Mitogen-activated protein kinase 10 MAPK10 Tchem Kinase -2.29568 193.3 384
C-X-C motif chemokine 10 CXCL10 Tbio Non-IDG -3.27118 1942.1 623