Development Level

Tbio 38 | 10,625
Tchem 23 | 1,890
Tdark 5 | 7,003
Tclin 3 | 602

IMPC Term

preweaning lethality, complete... 4 | 633
decreased circulating sodium l... 2 | 18
embryonic lethality prior to t... 2 | 187
increased leukocyte cell numbe... 2 | 37
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal skin condition 1 | 6
abnormal startle reflex 1 | 14
decreased bone mineral content 1 | 157
decreased circulating amylase ... 1 | 24
decreased circulating fructosa... 1 | 31
decreased fasted circulating g... 1 | 49
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 19
decreased thermal nociceptive ... 1 | 4
decreased total body fat amoun... 1 | 186
female infertility 1 | 34
increased KLRG1+ CD8 alpha bet... 1 | 2
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased thermal nociceptive ... 1 | 9
polydactyly 1 | 22
preweaning lethality, incomple... 1 | 260
small superior vagus ganglion 1 | 20
vertebral fusion 1 | 23

Disease

Cancer 33 | 2,346
psoriasis 32 | 6,685
ovarian cancer 30 | 8,484
glioblastoma 27 | 5,572
osteosarcoma 24 | 7,933
lung cancer 20 | 4,466
atypical teratoid / rhabdoid tumor 19 | 4,369
medulloblastoma, large-cell 19 | 6,234
pilocytic astrocytoma 17 | 3,086
Multiple Sclerosis 14 | 498
Influenza 13 | 142
juvenile dermatomyositis 12 | 1,189
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
pediatric high grade glioma 11 | 2,712
Melanoma 10 | 261
subependymal giant cell astrocytoma 10 | 2,287
Hepatitis C 9 | 90
Mammary Neoplasms 9 | 410
adult high grade glioma 9 | 2,148
cystic fibrosis 9 | 1,665
dermatomyositis 9 | 933
group 4 medulloblastoma 9 | 1,875
malignant mesothelioma 9 | 3,162
ulcerative colitis 9 | 2,087
Arthritis 8 | 248
Breast cancer 8 | 3,094
cutaneous lupus erythematosus 8 | 1,056
ependymoma 8 | 2,514
interstitial cystitis 8 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
lung carcinoma 8 | 2,844
oligodendroglioma 8 | 2,849
primary Sjogren syndrome 8 | 789
primitive neuroectodermal tumor 8 | 3,031
tuberculosis 8 | 1,557
Asthma 7 | 349
Lung disease 7 | 132
Reperfusion Injury 7 | 84
Rheumatoid Arthritis 7 | 1,160
diabetes mellitus 7 | 1,663
lung adenocarcinoma 7 | 2,713
posterior fossa group A ependymoma 7 | 1,511
Brain Ischemia 6 | 87
Hepatitis 6 | 61
Hepatitis B 6 | 103
Hypersensitivity reaction type II disease 6 | 235
Multiple myeloma 6 | 1,327
Severe acute respiratory syndrome 6 | 26
invasive ductal carcinoma 6 | 2,950
medulloblastoma 6 | 1,524
non-small cell lung cancer 6 | 2,798
pancreatic cancer 6 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
systemic lupus erythematosus 6 | 156
Cholestasis 5 | 93
Encephalitis 5 | 54
Gaucher disease type 1 5 | 171
Inflammatory bowel disease 5 | 142
Kidney disease 5 | 396
Leukopenia 5 | 42
Pancreatic Neoplasm 5 | 79
Stomach Neoplasms 5 | 282
Vascular disease 5 | 281
active Crohn's disease 5 | 918
acute myeloid leukemia 5 | 780
acute quadriplegic myopathy 5 | 1,157
breast carcinoma 5 | 1,614
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
posterior fossa group B ependymoma 5 | 1,530
Adenocarcinoma 4 | 115
Anemia 4 | 252
Ankylosing spondylitis 4 | 138
Brain disease 4 | 83
Carcinoma 4 | 2,147
Colonic Neoplasms 4 | 126
Colorectal Neoplasms 4 | 217
Crohn's disease 4 | 304
Diabetes Mellitus, Non-Insulin-Dependent 4 | 157
Diarrhea 4 | 155
Drug-Induced Liver Injury 4 | 118
Liver carcinoma 4 | 217
Liver neoplasms 4 | 109
Lung Neoplasms 4 | 171
Myocardial Ischemia 4 | 169
Neoplasms, Experimental 4 | 33
Neoplastic Cell Transformation 4 | 81
Neurodegenerative disease 4 | 383
Obesity 4 | 616
Osteoporosis 4 | 257
Pick disease 4 | 1,893
Thyroid Neoplasm 4 | 33
Toxic encephalopathy 4 | 131
adrenocortical carcinoma 4 | 1,427
astrocytic glioma 4 | 2,241
astrocytoma 4 | 1,493
colon cancer 4 | 1,475
glioblastoma multiforme 4 | 347
group 3 medulloblastoma 4 | 2,254
pituitary cancer 4 | 1,972

Tissue

Nervous System 69 | 18,561
Digestive Tract 67 | 18,473
Female tissues 67 | 18,647
Urinary Tract 67 | 18,444
Skin and soft tissues 64 | 18,115
Blood and immune system 63 | 17,995
Endocrine System 63 | 18,512
Cardiovascular System 61 | 17,958
Liver and Pancreas 61 | 18,136
Respiratory system 59 | 17,484
Male tissues 55 | 17,969

Target Family

Non-IDG 38 | 11,971
Kinase 15 | 634
Enzyme 12 | 4,146
Transcription Factor 4 | 1,400

KEGG Pathway

RIG-I-like receptor signaling ... 69 | 69
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.85843 68.9 516
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34160 1960.9 1181
Mitogen-activated protein kinase 13 MAPK13 Tchem Kinase -2.46715 317.1 405
C-X-C motif chemokine 10 CXCL10 Tchem Non-IDG -3.18828 1760.4 488
NF-kappa-B essential modulator IKBKG Tchem Kinase -3.03588 1121.7 849
Interferon alpha-7 IFNA7 Tdark Non-IDG -0.67991 3.90 46
Interferon alpha-10 IFNA10 Tbio Non-IDG -1.24816 16.2 115
Interferon alpha-2 IFNA2 Tbio Non-IDG -3.37730 2309.7 710
Interferon alpha-1/13 IFNA13 Tbio Non-IDG -3.85630 7619.4 379
Inhibitor of nuclear factor kappa-B kinase subunit alpha CHUK Tchem Kinase -2.35199 201.1 1028