Development Level

Tbio 70 | 11,445
Tchem 13 | 1,598
Tclin 11 | 613
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, complete... 15 | 979
embryonic lethality prior to o... 10 | 239
embryonic lethality prior to t... 5 | 278
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
decreased bone mineral content 3 | 151
increased bone mineral content 3 | 108
increased mean corpuscular vol... 3 | 92
preweaning lethality, incomple... 3 | 499
decreased circulating sodium l... 2 | 22
decreased mean corpuscular hem... 2 | 31
decreased mean corpuscular vol... 2 | 79
embryonic growth retardation 2 | 106
increased circulating HDL chol... 2 | 80
increased mean corpuscular hem... 2 | 96
prenatal lethality prior to he... 2 | 87
abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal ear morphology 1 | 9
abnormal embryonic autopod pla... 1 | 2
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal hair growth 1 | 10
abnormal heart morphology 1 | 162
abnormal placenta morphology 1 | 5
abnormal posture 1 | 2
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
abnormal stomach morphology 1 | 10
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating glycerol... 1 | 16
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged urinary bladder 1 | 8
female infertility 1 | 60
increased T cell number 1 | 6
increased bone mineral density 1 | 72
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
long tibia 1 | 25
male infertility 1 | 123
prenatal lethality 1 | 28
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
thin ventricular wall 1 | 24
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

ovarian cancer 53 | 8,520
osteosarcoma 43 | 7,950
Carcinoma 42 | 11,493
lung cancer 39 | 4,740
medulloblastoma, large-cell 39 | 6,241
group 3 medulloblastoma 33 | 4,104
psoriasis 32 | 6,694
glioblastoma 28 | 5,792
atypical teratoid / rhabdoid tumor 26 | 5,112
primitive neuroectodermal tumor 23 | 3,035
ependymoma 22 | 4,679
Autosomal recessive predisposition 20 | 1,442
non-small cell lung cancer 20 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
Breast cancer 18 | 3,578
Cancer 18 | 2,499
malignant mesothelioma 18 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
tuberculosis 17 | 2,010
invasive ductal carcinoma 16 | 2,951
Kidney cancer 13 | 2,613
adult high grade glioma 13 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
Multiple myeloma 12 | 1,332
interstitial cystitis 12 | 2,312
oligodendroglioma 12 | 2,850
pancreatic cancer 12 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Colorectal Neoplasms 11 | 243
lung adenocarcinoma 11 | 2,716
pediatric high grade glioma 11 | 1,064
Astrocytoma, Pilocytic 10 | 3,081
ductal carcinoma in situ 10 | 1,745
Endometriosis 9 | 540
Intellectual disability 9 | 1,016
Pick disease 9 | 1,894
Waldenstrons macroglobulinemia 9 | 765
breast carcinoma 9 | 1,638
colon cancer 9 | 1,478
diabetes mellitus 9 | 1,728
ulcerative colitis 9 | 1,819
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
adrenocortical carcinoma 8 | 1,428
group 4 medulloblastoma 8 | 1,855
lung carcinoma 8 | 2,843
non primary Sjogren syndrome sicca 8 | 891
subependymal giant cell astrocytoma 8 | 2,287
Atopic dermatitis 7 | 952
Carcinoma, Hepatocellular 7 | 228
Cerebellar Ataxia 7 | 304
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Liver carcinoma 7 | 240
Mental and motor retardation 7 | 608
Stomach Neoplasms 7 | 300
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
nasopharyngeal carcinoma 7 | 1,058
Adenocarcinoma of lung 6 | 142
Adenocarcinoma of pancreas 6 | 14
Disease Models, Animal 6 | 155
Epilepsy 6 | 792
Metastatic Breast Carcinoma 6 | 21
Seizures 6 | 596
Treacher Collins syndrome 6 | 27
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
pituitary cancer 6 | 1,972
primary Sjogren syndrome 6 | 735
primary pancreatic ductal adenocarcinoma 6 | 1,109
Acute lymphoid leukemia 5 | 25
Anemia 5 | 365
Breast Neoplasms 5 | 445
Cleft Palate 5 | 271
Downward slant of palpebral fissure 5 | 158
Hereditary spherocytosis type 5 5 | 12
Hypoplastic mandible condyle 5 | 275
Malignant tumor of ovary 5 | 25
Mammary Neoplasms 5 | 425
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Muscle hypotonia 5 | 571
Myopia 5 | 176
Progressive disorder 5 | 142
acute myeloid leukemia 5 | 783
dermatomyositis 5 | 966
gastric carcinoma 5 | 807
juvenile dermatomyositis 5 | 1,187
Failure to gain weight 4 | 365
Pediatric failure to thrive 4 | 365
Schizophrenia 4 | 1,160
Uranostaphyloschisis 4 | 167
active Crohn's disease 4 | 922
chronic rhinosinusitis 4 | 512
hepatocellular carcinoma 4 | 547
pancreatic carcinoma 4 | 562

Tissue

Digestive Tract 99 | 17,369
Endocrine System 99 | 18,159
Female tissues 99 | 17,400
Liver and Pancreas 99 | 16,750
Male tissues 99 | 17,142
Skin and soft tissues 99 | 17,230
Urinary Tract 99 | 16,678
Blood and immune system 98 | 16,909
Nervous System 98 | 16,725
Respiratory system 98 | 16,393
Cardiovascular System 95 | 15,192

Target Family

Enzyme 83 | 4,145
Kinase 15 | 634
Non-IDG 2 | 12,091

KEGG Pathway

Pyrimidine metabolism 100 | 100
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Uridine-cytidine kinase-like 1 UCKL1 Tdark Kinase -0.15970 2.21 110
DNA-directed RNA polymerase II subunit RPB2 POLR2B Tbio Enzyme -2.49730 299.8 149
CTP synthase 1 CTPS1 Tbio Enzyme -2.29349 196.5 107
DNA-directed RNA polymerase III subunit RPC2 POLR3B Tbio Enzyme -1.25377 19.0 105
Cytosolic 5'-nucleotidase 1B NT5C1B Tbio Enzyme -1.94015 85.4 93
DNA polymerase delta subunit 4 POLD4 Tbio Enzyme -0.84887 7.32 24
Dihydropyrimidine dehydrogenase [NADP(+)] DPYD Tclin Enzyme -2.62432 395.0 159
DNA-directed RNA polymerases I, II, and III subunit RPABC2 POLR2F Tbio Enzyme -1.13403 13.9 68
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] NUDT2 Tbio Enzyme -1.25186 18.4 144
Cytosolic 5'-nucleotidase 1A NT5C1A Tbio Enzyme -2.15798 140.3 139