Development Level

Tbio 64 | 10,625
Tchem 19 | 1,890
Tclin 11 | 602
Tdark 8 | 7,003

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

preweaning lethality, complete... 9 | 633
embryonic lethality prior to o... 7 | 148
embryonic lethality prior to t... 4 | 187
increased bone mineral content 4 | 92
abnormal behavior 2 | 226
abnormal embryo size 2 | 112
decreased bone mineral content 2 | 157
decreased circulating glycerol... 2 | 19
decreased lumbar vertebrae num... 2 | 62
decreased total body fat amoun... 2 | 186
increased circulating sodium l... 2 | 71
increased mean corpuscular hem... 2 | 93
increased sacral vertebrae num... 2 | 62
prenatal lethality prior to he... 2 | 64
preweaning lethality, incomple... 2 | 260
abnormal bone structure 1 | 131
abnormal clavicle morphology 1 | 5
abnormal epididymis morphology 1 | 31
abnormal hair growth 1 | 8
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal retinal vasculature m... 1 | 15
abnormal rib morphology 1 | 28
abnormal sacral vertebrae morp... 1 | 5
decreased B cell number 1 | 30
decreased CD8-positive, naive ... 1 | 5
decreased KLRG1-positive CD4-p... 1 | 1
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased cervical vertebrae n... 1 | 12
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased mean platelet volume 1 | 12
decreased monocyte cell number 1 | 28
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
embryonic growth retardation 1 | 28
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
enlarged urinary bladder 1 | 4
hypoactivity 1 | 89
immune system phenotype 1 | 17
increased T cell number 1 | 15
increased circulating HDL chol... 1 | 63
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating glycerol... 1 | 11
increased circulating serum al... 1 | 25
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased memory CD4-positive,... 1 | 3
increased red blood cell distr... 1 | 21
polydactyly 1 | 22
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

ovarian cancer 55 | 8,484
osteosarcoma 44 | 7,933
lung cancer 40 | 4,466
medulloblastoma, large-cell 39 | 6,234
psoriasis 32 | 6,685
glioblastoma 29 | 5,572
group 3 medulloblastoma 24 | 2,254
primitive neuroectodermal tumor 23 | 3,031
atypical teratoid / rhabdoid tumor 22 | 4,369
pediatric high grade glioma 21 | 2,712
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,289
non-small cell lung cancer 20 | 2,798
Cancer 19 | 2,346
malignant mesothelioma 19 | 3,162
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
Breast cancer 16 | 3,094
invasive ductal carcinoma 16 | 2,950
tuberculosis 16 | 1,557
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,956
Colorectal Neoplasms 12 | 217
Multiple myeloma 12 | 1,327
interstitial cystitis 12 | 2,299
oligodendroglioma 12 | 2,849
pancreatic cancer 12 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
lung adenocarcinoma 11 | 2,713
posterior fossa group A ependymoma 11 | 1,511
Carcinoma 10 | 2,147
ductal carcinoma in situ 10 | 1,745
ependymoma 10 | 2,514
pilocytic astrocytoma 10 | 3,086
ulcerative colitis 10 | 2,087
Endometriosis 9 | 535
Pick disease 9 | 1,893
Waldenstrons macroglobulinemia 9 | 765
breast carcinoma 9 | 1,614
colon cancer 9 | 1,475
sonic hedgehog group medulloblastoma 9 | 1,482
adrenocortical carcinoma 8 | 1,427
atypical teratoid/rhabdoid tumor 8 | 1,095
diabetes mellitus 8 | 1,663
lung carcinoma 8 | 2,844
medulloblastoma 8 | 1,524
non primary Sjogren syndrome sicca 8 | 840
subependymal giant cell astrocytoma 8 | 2,287
Atopic dermatitis 7 | 944
Liver carcinoma 7 | 217
Stomach Neoplasms 7 | 282
astrocytic glioma 7 | 2,241
astrocytoma 7 | 1,493
group 4 medulloblastoma 7 | 1,875
nasopharyngeal carcinoma 7 | 1,056
posterior fossa group B ependymoma 7 | 1,530
Adenocarcinoma of pancreas 6 | 12
Metastatic Breast Carcinoma 6 | 21
cutaneous lupus erythematosus 6 | 1,056
cystic fibrosis 6 | 1,665
pituitary cancer 6 | 1,972
primary Sjogren syndrome 6 | 789
primary pancreatic ductal adenocarcinoma 6 | 1,271
Acute lymphoid leukemia 5 | 25
Malignant tumor of ovary 5 | 25
Mammary Neoplasms 5 | 410
Treacher Collins syndrome 5 | 29
acute myeloid leukemia 5 | 780
dermatomyositis 5 | 933
gastric carcinoma 5 | 832
juvenile dermatomyositis 5 | 1,189
Acute promyelocytic leukemia, FAB M3 4 | 10
Colonic Neoplasms 4 | 126
IGA Glomerulonephritis 4 | 454
Leukodystrophy 4 | 30
Orotic aciduria 4 | 16
Prostatic Neoplasms 4 | 471
active Crohn's disease 4 | 918
chronic rhinosinusitis 4 | 512
esophageal adenocarcinoma 4 | 737
hepatocellular carcinoma 4 | 532
pancreatic carcinoma 4 | 567
Acute myeloid leukemia, disease 3 | 16
Anemia 3 | 252
Beta thalassemia 3 | 19
Chronic Lymphocytic Leukemia 3 | 242
Chronic progressive external ophthalmoplegia 3 | 18
Diarrhea 3 | 155
Hereditary spherocytosis 3 | 20
Malignant tumor of stomach 3 | 12
Neoplasm Metastasis 3 | 138
Pancreatic Neoplasm 3 | 79
Peripheral Neuropathy 3 | 303
Rheumatoid Arthritis 3 | 1,160
Schizophrenia 3 | 501
acute quadriplegic myopathy 3 | 1,157
adult high grade glioma 3 | 2,148
cystic fibrosis and chronic rhinosinusitis 3 | 213
gastric cancer 3 | 430
inflammatory breast cancer 3 | 404
mucosa-associated lymphoid tissue lymphoma 3 | 480
non-small cell lung carcinoma 3 | 413
progressive supranuclear palsy 3 | 674

Tissue

Endocrine System 102 | 18,512
Male tissues 102 | 17,969
Blood and immune system 101 | 17,995
Cardiovascular System 101 | 17,958
Digestive Tract 101 | 18,473
Female tissues 101 | 18,647
Liver and Pancreas 101 | 18,136
Nervous System 101 | 18,561
Respiratory system 101 | 17,484
Urinary Tract 101 | 18,444
Skin and soft tissues 100 | 18,115

Target Family

Enzyme 86 | 4,146
Kinase 15 | 634
Non-IDG 1 | 11,971

KEGG Pathway

Pyrimidine metabolism 102 | 102
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Uridine-cytidine kinase 2 UCK2 Tbio Kinase -1.39159 27.7 106
DNA-directed RNA polymerase II subunit RPB7 POLR2G Tbio Enzyme -1.74939 59.4 153
Ectonucleoside triphosphate diphosphohydrolase 1 ENTPD1 Tbio Enzyme -2.59508 482.4 411
Cytosolic purine 5'-nucleotidase NT5C2 Tchem Enzyme -2.20716 156.4 131
DNA primase large subunit PRIM2 Tbio Enzyme 0.00000 76
Ribonucleoside-diphosphate reductase subunit M2 B RRM2B Tbio Enzyme -1.87012 86.4 226
DNA primase small subunit PRIM1 Tbio Enzyme -0.88906 8.05 121
DNA-directed RNA polymerase II subunit RPB4 POLR2D Tdark Enzyme -0.50937 3.13 114
Cytosolic 5'-nucleotidase 3A NT5C3A Tbio Enzyme -1.93828 85.1 79
DNA-directed RNA polymerases I, II, and III subunit RPABC5 POLR2L Tbio Enzyme -0.98287 10.2 60