Development Level

Tbio 14 | 11,445
Tdark 8 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

decreased lean body mass 2 | 135
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased total body fat amoun... 2 | 134
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
decreased circulating HDL chol... 1 | 68
decreased circulating insulin ... 1 | 76
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101

Disease

ovarian cancer 16 | 8,520
osteosarcoma 13 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Multiple myeloma 10 | 1,332
glioblastoma 10 | 5,792
Carcinoma 9 | 11,493
psoriasis 7 | 6,694
Breast cancer 6 | 3,578
ependymoma 6 | 4,679
group 3 medulloblastoma 6 | 4,104
medulloblastoma, large-cell 6 | 6,241
atypical teratoid / rhabdoid tumor 5 | 5,112
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
pancreatic cancer 5 | 2,398
Waldenstrons macroglobulinemia 4 | 765
active Crohn's disease 4 | 922
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
dermatomyositis 4 | 966
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
primitive neuroectodermal tumor 4 | 3,035
Alzheimer's disease 3 | 658
Pick disease 3 | 1,894
Polycystic liver disease 3 | 16
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive polycystic kidney disease 2 | 41
Craniofacial Abnormalities 2 | 151
Isolated growth hormone deficiency 2 | 30
Pituitary hypoplasia 2 | 23
Spinocerebellar ataxia type 2 2 | 23
acute myeloid leukemia 2 | 783
diabetes mellitus 2 | 1,728
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
non primary Sjogren syndrome sicca 2 | 891
oligodendroglioma 2 | 2,850
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287
Abdomen distended 1 | 43
Arsenic Poisoning 1 | 62
Autistic Disorder 1 | 364
Bipolar I disorder 1 | 23
Carcinoma, Hepatocellular 1 | 228
Cardiovascular Diseases 1 | 59
Cataract 8 multiple types 1 | 33
Chemical and Drug Induced Liver Injury 1 | 195
Cholestasis 1 | 155
Chronic obstructive pulmonary disease 1 | 184
Congenital deafness 1 | 185
Cystic kidney 1 | 30
Deafness 1 | 198
Dermatologic disorders 1 | 93
Diphtheria 1 | 40
Esophageal Squamous Cell Carcinoma 1 | 77
Eye disease 1 | 62
Fatty liver disease 1 | 103
Gaucher disease type 1 1 | 180
Gilles de la Tourette syndrome 1 | 47
Hearing Loss, Partial 1 | 185
Hepatomegaly 1 | 285
Hypercalcemia 1 | 59
Hypoplastic myelodysplasia 1 | 18
Kidney disease 1 | 430
Liver carcinoma 1 | 240
Liver disease 1 | 237
MYELODYSPLASTIC SYNDROME 1 | 53
Myocardial Infarction 1 | 151
Myopathy 1 | 185
Orotic aciduria 1 | 18
Parkinson's disease 1 | 392
Pellagra 1 | 26
Polycystic ovary syndrome 1 | 360
Shwachman-Diamond syndrome 1 | 17
Skin Diseases 1 | 71
Squamous cell carcinoma of esophagus 1 | 77
Toxic encephalopathy 1 | 141
Type 2 diabetes mellitus 1 | 272
Yellow fever 1 | 16
adrenocortical carcinoma 1 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
breast carcinoma 1 | 1,638
glioblastoma multiforme 1 | 142
hearing impairment 1 | 199
pancreatic carcinoma 1 | 562
progressive supranuclear palsy 1 | 676
substance-related disorder 1 | 162
tuberculosis and treatment for 3 months 1 | 179

Tissue

Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678

Target Family

Non-IDG 16 | 12,091
Enzyme 7 | 4,145

KEGG Pathway

Protein export 23 | 23
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Signal peptidase complex subunit 1 SPCS1 Tdark Enzyme -0.80900 6.46 44
Signal recognition particle subunit SRP72 SRP72 Tbio Non-IDG -1.41325 24.6 67
Signal recognition particle 54 kDa protein SRP54 Tbio Non-IDG -2.15322 140.3 140
Signal recognition particle 14 kDa protein SRP14 Tbio Non-IDG -1.25810 14.5 106
Mitochondrial inner membrane protease subunit 2 IMMP2L Tbio Enzyme -1.31827 19.8 98
Signal recognition particle 19 kDa protein SRP19 Tbio Non-IDG 0.30 0.78 109
Signal peptidase complex subunit 2 SPCS2 Tdark Enzyme -0.26503 1.68 51
Mitochondrial inner membrane protein OXA1L OXA1L Tbio Non-IDG -2.94340 838.0 141
Mitochondrial inner membrane protease subunit 1 IMMP1L Tdark Enzyme -0.61904 4.11 64
Signal recognition particle subunit SRP68 SRP68 Tbio Non-IDG -1.13992 13.4 83