Development Level

Tbio 50 | 11,445
Tchem 22 | 1,598
Tclin 13 | 613
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
abnormal femur morphology 3 | 14
abnormal kidney morphology 3 | 65
impaired glucose tolerance 3 | 75
decreased erythrocyte cell num... 2 | 62
decreased total body fat amoun... 2 | 207
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal ear morphology 1 | 9
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tibia morphology 1 | 14
abnormal ulna morphology 1 | 8
abnormal urinary bladder morph... 1 | 11
cataract 1 | 92
cystolithiasis 1 | 3
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating chloride... 1 | 30
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
dilated heart left ventricle 1 | 11
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged urinary bladder 1 | 8
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased vertical activity 1 | 24
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
short tibia 1 | 97
small kidney 1 | 16

Disease

Carcinoma 68 | 11,493
ovarian cancer 44 | 8,520
intraductal papillary-mucinous carcinoma (IPMC) 34 | 2,989
lung cancer 34 | 4,740
atypical teratoid / rhabdoid tumor 33 | 5,112
glioblastoma 33 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
osteosarcoma 33 | 7,950
Kidney cancer 32 | 2,613
medulloblastoma, large-cell 32 | 6,241
psoriasis 32 | 6,694
Astrocytoma, Pilocytic 30 | 3,081
lung adenocarcinoma 30 | 2,716
Breast cancer 29 | 3,578
ependymoma 29 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
pancreatic cancer 28 | 2,398
cystic fibrosis 25 | 1,696
interstitial cystitis 24 | 2,312
malignant mesothelioma 23 | 3,232
primitive neuroectodermal tumor 23 | 3,035
ulcerative colitis 23 | 1,819
pituitary cancer 22 | 1,972
adult high grade glioma 21 | 3,801
invasive ductal carcinoma 21 | 2,951
non-small cell lung cancer 21 | 2,890
Autosomal recessive predisposition 20 | 1,442
Duchenne muscular dystrophy 20 | 601
gastric carcinoma 20 | 807
group 3 medulloblastoma 18 | 4,104
Skin cancer 17 | 469
oligodendroglioma 17 | 2,850
Melanoma 15 | 711
breast carcinoma 15 | 1,638
colon cancer 15 | 1,478
lung carcinoma 15 | 2,843
nasopharyngeal carcinoma 15 | 1,058
subependymal giant cell astrocytoma 15 | 2,287
Short stature 14 | 531
diabetes mellitus 14 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
urothelial carcinoma 14 | 318
Degenerative polyarthritis 13 | 115
Hypertension 13 | 396
Liver Cirrhosis, Experimental 13 | 769
ductal carcinoma in situ 13 | 1,745
primary pancreatic ductal adenocarcinoma 13 | 1,109
Hypoplastic mandible condyle 12 | 275
Mandibular hypoplasia 12 | 275
Micrognathism 12 | 275
Myopia 12 | 176
Pick disease 12 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 510
juvenile dermatomyositis 12 | 1,187
Becker muscular dystrophy 11 | 191
Congestive heart failure 11 | 113
Hypertensive disease 11 | 292
Joint hyperflexibility 11 | 78
Liver cancer 11 | 604
Osteoarthritis 11 | 184
active Crohn's disease 11 | 922
interstitial lung disease 11 | 298
Abortion, Spontaneous 10 | 109
Atopic dermatitis 10 | 952
Atrial Fibrillation 10 | 124
Cancer 10 | 2,499
Kidney disease 10 | 430
Spontaneous abortion 10 | 113
adrenocortical carcinoma 10 | 1,428
astrocytic glioma 10 | 2,597
cutaneous lupus erythematosus 10 | 1,057
tuberculosis 10 | 2,010
Acquired scoliosis 9 | 281
Cataract 9 | 297
Chronic heart failure 9 | 46
Curvature of spine 9 | 282
Epilepsy 9 | 792
Hyperkyphosis 9 | 111
Kyphosis deformity of spine 9 | 114
Lens Opacities 9 | 231
Muscle hypotonia 9 | 571
Platyspondyly 9 | 56
Respiratory Insufficiency 9 | 132
Respiratory function loss 9 | 121
Seizures 9 | 596
Sensorineural Hearing Loss (disorder) 9 | 284
limb girdle muscular dystrophy 2A 9 | 213
nephrosclerosis 9 | 333
pediatric high grade glioma 9 | 1,064
Contracture 8 | 96
Contracture of joint 8 | 93
Flexion contracture 8 | 93
Flexion contractures of joints 8 | 93
Hypotrophic malar bone 8 | 129
Malar flattening 8 | 129
Pancreatitis 8 | 123
Poisoning by digitalis glycoside 8 | 8
esophageal adenocarcinoma 8 | 737
group 4 medulloblastoma 8 | 1,855
pterygium 8 | 76

Tissue

Digestive Tract 90 | 17,369
Endocrine System 90 | 18,159
Male tissues 90 | 17,142
Liver and Pancreas 89 | 16,750
Skin and soft tissues 89 | 17,230
Blood and immune system 88 | 16,909
Female tissues 88 | 17,400
Nervous System 86 | 16,725
Urinary Tract 86 | 16,678
Respiratory system 81 | 16,393
Cardiovascular System 77 | 15,192

Target Family

Non-IDG 38 | 12,091
Transporter 24 | 473
Enzyme 23 | 4,145
Ion Channel 5 | 344

KEGG Pathway

Protein digestion and absorpti... 90 | 90
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Potassium voltage-gated channel subfamily E member 3 KCNE3 Tbio Ion Channel -1.63683 41.4 75
Collagen alpha-1(XXI) chain COL21A1 Tbio Non-IDG -0.67130 4.90 89
Collagen alpha-1(XII) chain COL12A1 Tbio Non-IDG -1.36571 21.4 38
Collagen alpha-1(XV) chain COL15A1 Tbio Non-IDG -1.18716 15.5 74
Mast cell carboxypeptidase A CPA3 Tchem Enzyme -1.72972 50.2 151
Carboxypeptidase B CPB1 Tchem Enzyme -2.97696 883.0 228
Carboxypeptidase A1 CPA1 Tchem Enzyme -1.95541 84.1 265
Collagen alpha-1(XVIII) chain COL18A1 Tbio Non-IDG -3.18339 1561.4 433
Sodium/potassium-transporting ATPase subunit gamma FXYD2 Tclin Enzyme -1.58017 39.0 64