Development Level

Tbio 36 | 11,445
Tclin 5 | 613
Tdark 3 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavioral response t... 1 | 66
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
decreased circulating choleste... 1 | 93
decreased circulating total pr... 1 | 49
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased erythrocyte cell num... 1 | 39
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36

Disease

ovarian cancer 34 | 8,520
Multiple myeloma 24 | 1,332
lung cancer 21 | 4,740
psoriasis 20 | 6,694
Carcinoma 17 | 11,493
HIV Infections 16 | 102
osteosarcoma 15 | 7,950
glioblastoma 14 | 5,792
dermatomyositis 10 | 966
Waldenstrons macroglobulinemia 9 | 765
Breast cancer 8 | 3,578
malignant mesothelioma 8 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
diabetes mellitus 7 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Cancer 6 | 2,499
ependymoma 6 | 4,679
non-small cell lung cancer 6 | 2,890
Liver Cirrhosis, Experimental 5 | 769
Mantle cell lymphoma 5 | 23
astrocytoma 5 | 1,146
atypical teratoid / rhabdoid tumor 5 | 5,112
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
medulloblastoma, large-cell 5 | 6,241
non primary Sjogren syndrome sicca 5 | 891
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Osteoporosis 4 | 363
Pick disease 4 | 1,894
adult high grade glioma 4 | 3,801
hepatocellular carcinoma 4 | 547
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
primary Sjogren syndrome 4 | 735
Astrocytoma, Pilocytic 3 | 3,081
Congestive heart failure 3 | 113
active Crohn's disease 3 | 922
cutaneous lupus erythematosus 3 | 1,057
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
Anemia 2 | 365
Animal Mammary Neoplasms 2 | 136
Autosomal recessive predisposition 2 | 1,442
Crohn's disease 2 | 321
Diarrhea 2 | 253
Esophageal Squamous Cell Carcinoma 2 | 77
Heart failure 2 | 162
Hepatitis B 2 | 108
Major Depressive Disorder 2 | 301
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Pneumonia 2 | 174
Primary immunodeficiency disease 2 | 54
Rheumatoid arthritis 2 | 1,191
Squamous cell carcinoma of esophagus 2 | 77
Stevens-Johnson syndrome 2 | 92
Unipolar Depression 2 | 250
astrocytic glioma 2 | 2,597
chronic kidney disease 2 | 90
esophageal adenocarcinoma 2 | 737
sarcoidosis 2 | 370
tuberculosis and treatment for 3 months 2 | 179
ulcerative colitis 2 | 1,819
Acrodermatitis 1 | 5
Acute coronary syndrome 1 | 39
Aplastic Anemia 1 | 21
Appendicitis 1 | 15
Aspergillosis 1 | 26
Basal ganglia calcification 1 | 27
Chlamydia 1 | 21
Clostridium difficile colitis 1 | 12
Cryptococcosis 1 | 18
Diabetes Mellitus, Insulin-Dependent 1 | 48
Diabetes Mellitus, Type 1 1 | 43
Disturbance in mood 1 | 3
ESR raised 1 | 20
Flexion contracture - elbow 1 | 32
Hepatitis 1 | 67
Hyperostosis 1 | 18
Hyperthyroidism 1 | 53
Increased size of palpebral fissures 1 | 9
Large eyes 1 | 9
Legionnaires' disease 1 | 20
Leishmaniasis, Visceral 1 | 13
Leprosy 1 | 73
Lichen planus 1 | 16
Lipodystrophy 1 | 40
Multiple, subcutaneous nodules 1 | 53
Oral Submucous Fibrosis 1 | 20
Oral hairy leukoplakia 1 | 6
Paranoid personality disorder 1 | 5
Peripheral Nervous System Diseases 1 | 52
Subcutaneous nodule 1 | 53
Thymic carcinoma 1 | 2
Tuberous sclerosis 1 | 19

Tissue

Endocrine System 45 | 18,159
Blood and immune system 44 | 16,909
Digestive Tract 44 | 17,369
Female tissues 44 | 17,400
Male tissues 44 | 17,142
Nervous System 44 | 16,725
Respiratory system 44 | 16,393
Urinary Tract 44 | 16,678
Cardiovascular System 43 | 15,192
Liver and Pancreas 43 | 16,750
Skin and soft tissues 43 | 17,230

Target Family

Enzyme 36 | 4,145
Non-IDG 10 | 12,091

KEGG Pathway

Proteasome 46 | 46
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
Putative protein SEM1, isoform 2 SEM1 Tbio Non-IDG 0.30 0.49 109
26S proteasome regulatory subunit 10B PSMC6 Tbio Enzyme -2.65165 339.0 214
Proteasome subunit alpha type-7 PSMA7 Tbio Enzyme -2.71627 496.7 288
Proteasome subunit alpha type-6 PSMA6 Tbio Enzyme -2.80973 614.4 288
26S proteasome complex subunit SEM1 SEM1 Tbio Non-IDG -2.83524 645.6 109
26S proteasome non-ATPase regulatory subunit 11 PSMD11 Tbio Enzyme -1.13234 13.3 211
Proteasome subunit alpha type-3 PSMA3 Tbio Enzyme -1.20981 15.8 181