Development Level

Tbio 19 | 11,651
Tchem 10 | 1,388
Tclin 6 | 612

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased body weight 2 | 161
decreased total body fat amoun... 2 | 207
embryonic lethality prior to t... 2 | 278
abnormal anxiety-related respo... 1 | 1
abnormal coat appearance 1 | 31
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal social-conspecific in... 1 | 3
abnormal vertebrae morphology 1 | 18
absent seminal vesicle 1 | 4
cardiovascular system phenotyp... 1 | 36
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
female infertility 1 | 60
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 8
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
shortened RR interval 1 | 17
small uterus 1 | 3

Disease

Carcinoma 25 | 11,493
psoriasis 18 | 6,694
lung cancer 17 | 4,740
ovarian cancer 17 | 8,520
glioblastoma 16 | 5,792
lung carcinoma 15 | 2,843
Cancer 14 | 2,499
Alzheimer's disease 13 | 658
invasive ductal carcinoma 13 | 2,951
malignant mesothelioma 13 | 3,232
non-small cell lung cancer 13 | 2,890
lung adenocarcinoma 12 | 2,716
medulloblastoma, large-cell 12 | 6,241
osteosarcoma 12 | 7,950
tuberculosis 12 | 2,010
Schizophrenia 11 | 1,160
Astrocytoma, Pilocytic 10 | 3,081
Autosomal recessive predisposition 10 | 1,442
Liver Cirrhosis, Experimental 10 | 769
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
pancreatic cancer 10 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
primitive neuroectodermal tumor 10 | 3,035
ulcerative colitis 10 | 1,819
Depressive disorder 9 | 409
Vascular disease 9 | 319
juvenile dermatomyositis 9 | 1,187
Brain Ischemia 8 | 110
Down syndrome 8 | 499
Kidney cancer 8 | 2,613
Toxic encephalopathy 8 | 141
astrocytoma 8 | 1,146
atypical teratoid / rhabdoid tumor 8 | 5,112
dermatomyositis 8 | 966
diabetes mellitus 8 | 1,728
ependymoma 8 | 4,679
group 3 medulloblastoma 8 | 4,104
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
oligodendroglioma 8 | 2,850
subependymal giant cell astrocytoma 8 | 2,287
Bipolar Disorder 7 | 666
Breast cancer 7 | 3,578
Meningitis 7 | 67
Multiple myeloma 7 | 1,332
Obesity 7 | 678
Parkinson's disease 7 | 392
Prostatic Neoplasms 7 | 495
Rheumatoid arthritis 7 | 1,191
cutaneous lupus erythematosus 7 | 1,057
Arthritis 6 | 290
Kidney disease 6 | 430
Melanoma 6 | 711
Mental Depression 6 | 333
Neoplasm Invasiveness 6 | 161
Skin cancer 6 | 469
Stomach Neoplasms 6 | 300
acute quadriplegic myopathy 6 | 1,158
adrenocortical carcinoma 6 | 1,428
adult high grade glioma 6 | 3,801
colon cancer 6 | 1,478
cystic fibrosis 6 | 1,696
Alcoholic Intoxication, Chronic 5 | 289
Anemia 5 | 365
Asthma 5 | 385
Brain disease 5 | 96
Cardiomyopathies 5 | 110
Chemical and Drug Induced Liver Injury 5 | 195
Duchenne muscular dystrophy 5 | 601
Heart disease 5 | 306
Hyperalgesia 5 | 83
Hypersensitivity reaction type II disease 5 | 253
Immunologic Deficiency Syndromes 5 | 113
Inflammation 5 | 120
Liver disease 5 | 237
Lung Neoplasms 5 | 232
Multiple Sclerosis 5 | 540
Myocardial Infarction 5 | 151
Reperfusion Injury 5 | 86
astrocytic glioma 5 | 2,597
breast carcinoma 5 | 1,638
medulloblastoma 5 | 720
Atherosclerosis 4 | 291
Dementia 4 | 175
Dermatitis 4 | 157
Endometriosis 4 | 540
Eye disease 4 | 62
Hypertension 4 | 396
Lung disease 4 | 142
Major Depressive Disorder 4 | 301
Myocardial Ischemia 4 | 169
Pick disease 4 | 1,894
Unipolar Depression 4 | 250
Waldenstrons macroglobulinemia 4 | 765
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
pituitary cancer 4 | 1,972
primary pancreatic ductal adenocarcinoma 4 | 1,109

Tissue

Endocrine System 32 | 18,159
Liver and Pancreas 32 | 16,750
Urinary Tract 32 | 16,678
Male tissues 31 | 17,142
Blood and immune system 30 | 16,909
Digestive Tract 30 | 17,369
Female tissues 30 | 17,400
Respiratory system 30 | 16,393
Skin and soft tissues 30 | 17,230
Nervous System 29 | 16,725
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 23 | 12,091
Kinase 8 | 634
Enzyme 2 | 4,145
Transcription Factor 2 | 1,400

KEGG Pathway

Prion diseases 35 | 35
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Inactive caspase-12 CASP12 Tbio Enzyme -2.64252 415.1 429
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Stress-induced-phosphoprotein 1 STIP1 Tbio Non-IDG -2.00823 110.8 293
cAMP-dependent protein kinase catalytic subunit alpha PRKACA Tchem Kinase -1.09531 11.7 331
Complement component C9 C9 Tbio Non-IDG -1.88910 74.6 285
Complement C1q subcomponent subunit C C1QC Tbio Non-IDG -1.31972 17.9 168
Complement C1q subcomponent subunit B C1QB Tbio Non-IDG -1.66860 42.5 189
Neural cell adhesion molecule 1 NCAM1 Tbio Non-IDG -3.58910 3930.7 1982
Interleukin-1 beta IL1B Tclin Non-IDG -4.40738 24522.4 1588
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440