Development Level

Tbio 30 | 10,625
Tchem 9 | 1,890
Tdark 2 | 7,003

IMPC Phenotype

preweaning lethality, complete... 3 | 633
abnormal embryo size 2 | 112
embryonic lethality prior to o... 2 | 148
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal lung morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal sleep behavior 1 | 63
abnormal spinal cord morpholog... 1 | 8
decreased circulating iron lev... 1 | 25
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased total body fat amoun... 1 | 186
embryonic growth retardation 1 | 28
embryonic lethality prior to t... 1 | 187
enlarged heart atrium 1 | 2
increased blood urea nitrogen ... 1 | 44

Disease

psoriasis 22 | 6,685
ovarian cancer 17 | 8,491
Anemia 14 | 252
osteosarcoma 14 | 7,933
lung cancer 12 | 4,473
Cancer 11 | 2,346
medulloblastoma, large-cell 10 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
Bilirubin metabolic disorder 9 | 39
Sickle Cell Anemia 9 | 54
Porphyria 8 | 9
malignant mesothelioma 8 | 3,163
Hereditary coproporphyria 7 | 9
Pericholangitis 7 | 7
glioblastoma 7 | 5,572
tuberculosis 7 | 1,563
Acute intermittent porphyria 6 | 14
Erythropoietic protoporphyria 6 | 15
Variegate porphyria 6 | 10
atypical teratoid / rhabdoid tumor 6 | 4,369
Neonatal jaundice 5 | 15
Porphyria cutanea tarda 5 | 12
group 3 medulloblastoma 5 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
subependymal giant cell astrocytoma 5 | 2,287
Attention deficit hyperactivity disorder 4 | 156
Breast cancer 4 | 3,098
Cutaneous porphyria 4 | 6
Multiple myeloma 4 | 1,327
adult high grade glioma 4 | 2,148
astrocytoma 4 | 1,493
ependymoma 4 | 2,514
gastric carcinoma 4 | 832
lung adenocarcinoma 4 | 2,714
lung carcinoma 4 | 2,844
medulloblastoma 4 | 1,524
non primary Sjogren syndrome sicca 4 | 840
non-small cell lung cancer 4 | 2,798
pancreatic cancer 4 | 2,300
primitive neuroectodermal tumor 4 | 3,031
ulcerative colitis 4 | 2,087
Acute kidney injury 3 | 65
Contact Dermatitis 3 | 80
Gilbert syndrome 3 | 4
Hemochromatosis 3 | 55
Pick disease 3 | 1,893
Prostatic Neoplasms 3 | 471
Sideroblastic anemia 3 | 18
Toxic encephalopathy 3 | 131
adrenocortical carcinoma 3 | 1,427
astrocytic glioma 3 | 2,241
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,663
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
mucosa-associated lymphoid tissue lymphoma 3 | 480
pediatric high grade glioma 3 | 2,712
pituitary cancer 3 | 1,972
Adverse reaction to drug 2 | 54
Age related macular degeneration 2 | 84
Carcinoma 2 | 2,147
Cholestasis 2 | 93
Drug-Induced Liver Injury 2 | 118
Epilepsy 2 | 346
Fibrosis 2 | 40
Friedreich ataxia 2 | 23
Gaucher disease type 1 2 | 171
Heart disease 2 | 279
Hypertensive disease 2 | 193
Hypertrichosis 2 | 23
IGA Glomerulonephritis 2 | 454
Leigh disease 2 | 81
Liver disease 2 | 219
Liver diseases 2 | 66
Lung Neoplasms 2 | 171
Malignant neoplasm of urinary bladder 2 | 16
Melanoma 2 | 261
Neutropenia 2 | 78
Parkinson Disease 2 | 105
Prostate cancer 2 | 172
Schizophrenia 2 | 503
Stomach Neoplasms 2 | 282
Thalassemia 2 | 46
Urinary bladder cancer 2 | 34
Vascular disease 2 | 281
Waldenstrons macroglobulinemia 2 | 764
active Crohn's disease 2 | 918
acute quadriplegic myopathy 2 | 1,157
aldosterone-producing adenoma 2 | 664
atypical teratoid/rhabdoid tumor 2 | 1,095
colon cancer 2 | 1,475
cystic fibrosis 2 | 1,670
interstitial lung disease 2 | 292
nasopharyngeal carcinoma 2 | 1,056
pilocytic astrocytoma 2 | 3,086
posterior fossa group A ependymoma 2 | 1,511
pre-eclampsia 2 | 67
sarcoidosis 2 | 368

Tissue

Digestive Tract 41 | 18,472
Liver and Pancreas 41 | 18,135
Urinary Tract 41 | 18,443
Blood and immune system 39 | 17,994
Endocrine System 36 | 18,511
Female tissues 36 | 18,646
Skin and soft tissues 36 | 18,114
Nervous System 35 | 18,560
Male tissues 32 | 17,968
Cardiovascular System 30 | 17,957
Respiratory system 29 | 17,483

Target Family

Enzyme 38 | 4,146
Non-IDG 3 | 11,969

KEGG Pathway

Porphyrin and chlorophyll meta... 41 | 41
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UDP-glucuronosyltransferase 2B15 UGT2B15 Tchem Enzyme -1.77071 60.2 66
UDP-glucuronosyltransferase 2B7 UGT2B7 Tchem Enzyme -2.28111 210.7 117
Protoheme IX farnesyltransferase, mitochondrial COX10 Tbio Enzyme -1.58383 36.7 127
UDP-glucuronosyltransferase 2B28 UGT2B28 Tdark Enzyme -0.77637 6.83 37
Cytochrome c-type heme lyase HCCS Tbio Enzyme -3.34384 2181.1 196
Bifunctional glutamate/proline--tRNA ligase EPRS Tchem Enzyme -3.09040 1189.8 95
UDP-glucuronosyltransferase 2A3 UGT2A3 Tbio Enzyme -0.51548 2.63 79
UDP-glucuronosyltransferase 1-9 UGT1A9 Tbio Enzyme -2.14154 144.7 117
Probable glutamate--tRNA ligase, mitochondrial EARS2 Tbio Enzyme -2.38552 236.8 52
UDP-glucuronosyltransferase 1-5 UGT1A5 Tdark Enzyme -1.00381 9.71 15