Development Level

Tbio 40 | 11,445
Tchem 29 | 1,598
Tclin 5 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased mean corpuscular vol... 4 | 79
increased hemoglobin content 3 | 45
increased mean corpuscular hem... 3 | 96
preweaning lethality, complete... 3 | 979
abnormal lens morphology 2 | 81
abnormal spleen morphology 2 | 55
cataract 2 | 92
decreased body weight 2 | 161
decreased circulating creatini... 2 | 39
hyperactivity 2 | 148
increased mean corpuscular hem... 2 | 36
small testis 2 | 58
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal glucose homeostasis 1 | 4
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
absent testes 1 | 6
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased heart weight 1 | 62
increased kidney weight 1 | 6
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
thrombocytosis 1 | 27

Disease

Cancer 59 | 2,499
ovarian cancer 50 | 8,520
Carcinoma 46 | 11,493
psoriasis 42 | 6,694
glioblastoma 36 | 5,792
lung cancer 35 | 4,740
osteosarcoma 35 | 7,950
medulloblastoma, large-cell 31 | 6,241
Breast cancer 30 | 3,578
atypical teratoid / rhabdoid tumor 27 | 5,112
Prostatic Neoplasms 26 | 495
group 3 medulloblastoma 25 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
malignant mesothelioma 22 | 3,232
ependymoma 21 | 4,679
Schizophrenia 19 | 1,160
Stomach Neoplasms 19 | 300
Breast Neoplasms 18 | 445
Mammary Neoplasms 18 | 425
pancreatic cancer 18 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
primitive neuroectodermal tumor 17 | 3,035
Autosomal recessive predisposition 16 | 1,442
Lung Neoplasms 16 | 232
diabetes mellitus 16 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
invasive ductal carcinoma 16 | 2,951
nasopharyngeal carcinoma 16 | 1,058
tuberculosis 15 | 2,010
Epilepsy 14 | 792
Kidney cancer 14 | 2,613
Seizures 14 | 596
adrenocortical carcinoma 14 | 1,428
breast carcinoma 14 | 1,638
Adenoma 13 | 167
Vascular disease 13 | 319
adult high grade glioma 13 | 3,801
subependymal giant cell astrocytoma 13 | 2,287
Colorectal Neoplasms 12 | 243
Depressive disorder 12 | 409
Leukemia 12 | 104
ductal carcinoma in situ 12 | 1,745
juvenile dermatomyositis 12 | 1,187
lung adenocarcinoma 12 | 2,716
lung carcinoma 12 | 2,843
non-small cell lung cancer 12 | 2,890
Colonic Neoplasms 11 | 142
Fatigue 11 | 182
Liver Neoplasms, Experimental 11 | 59
Melanoma 11 | 711
Ovarian Neoplasms 11 | 102
Splenomegaly 11 | 190
colon cancer 11 | 1,478
pituitary cancer 11 | 1,972
Astrocytoma, Pilocytic 10 | 3,081
Bipolar Disorder 10 | 666
Carcinoma, Hepatocellular 10 | 228
Liver carcinoma 10 | 240
Lymphoma 10 | 81
Renal Cell Carcinoma 10 | 214
Squamous cell carcinoma 10 | 129
interstitial cystitis 10 | 2,312
non-small cell lung carcinoma 10 | 317
oligodendroglioma 10 | 2,850
ovarian neoplasm 10 | 99
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
ulcerative colitis 10 | 1,819
Alzheimer's disease 9 | 658
Asthma 9 | 385
Bladder Neoplasm 9 | 112
Carcinoma, Non-Small-Cell Lung 9 | 107
Carcinoma, Squamous Cell 9 | 110
Chemical and Drug Induced Liver Injury 9 | 195
Urinary Bladder Neoplasms 9 | 114
acute myeloid leukemia 9 | 783
cystic fibrosis 9 | 1,696
hepatocellular carcinoma 9 | 547
Arthritis 8 | 290
Basal cell carcinoma 8 | 54
Carcinoma, Renal Cell 8 | 124
Diffuse large B-cell lymphoma 8 | 39
Disease Models, Animal 8 | 155
Esophageal Neoplasms 8 | 69
Intellectual disability 8 | 1,016
Liver cancer 8 | 604
Multiple myeloma 8 | 1,332
Nausea and vomiting 8 | 97
Neoplasm Metastasis 8 | 168
Neurodegenerative disease 8 | 414
Papilloma 8 | 44
Toxic encephalopathy 8 | 141
Weight decreased 8 | 103
astrocytic glioma 8 | 2,597
cutaneous lupus erythematosus 8 | 1,057
group 4 medulloblastoma 8 | 1,855
Pick disease 7 | 1,894
acute quadriplegic myopathy 7 | 1,158
dermatomyositis 7 | 966
primary Sjogren syndrome 7 | 735
spina bifida 7 | 1,074

Tissue

Endocrine System 71 | 18,159
Blood and immune system 70 | 16,909
Digestive Tract 70 | 17,369
Female tissues 70 | 17,400
Male tissues 70 | 17,142
Respiratory system 70 | 16,393
Skin and soft tissues 70 | 17,230
Liver and Pancreas 69 | 16,750
Nervous System 69 | 16,725
Urinary Tract 69 | 16,678
Cardiovascular System 65 | 15,192

Target Family

Enzyme 35 | 4,145
Non-IDG 23 | 12,091
Kinase 13 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

KEGG Pathway

Platinum drug resistance 75 | 75
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Glutathione S-transferase theta-2 GSTT2 Tbio Enzyme -1.25193 16.8 0
High affinity copper uptake protein 1 SLC31A1 Tbio Transporter -1.98628 95.6 136
DNA topoisomerase 2-alpha TOP2A Tclin Enzyme -2.88264 723.0 847
Glutathione S-transferase A5 GSTA5 Tdark Enzyme -0.93224 8.65 46
Cytochrome c CYCS Tbio Non-IDG -3.76637 4945.6 833
DNA mismatch repair protein Msh6 MSH6 Tbio Epigenetic -2.72594 572.3 479
Microsomal glutathione S-transferase 1 MGST1 Tbio Enzyme -2.30082 197.5 146
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313