Development Level

Tbio 187 | 11,445
Tchem 23 | 1,598
Tclin 13 | 613
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to t... 7 | 278
embryonic lethality prior to o... 6 | 239
decreased total body fat amoun... 5 | 207
abnormal behavior 3 | 298
decreased lymphocyte cell numb... 3 | 83
decreased mean corpuscular hem... 3 | 50
increased bone mineral content 3 | 108
preweaning lethality, incomple... 3 | 499
abnormal lung morphology 2 | 26
abnormal seminal vesicle morph... 2 | 114
cardiovascular system phenotyp... 2 | 36
decreased blood urea nitrogen ... 2 | 51
decreased circulating amylase ... 2 | 28
decreased circulating bilirubi... 2 | 19
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
decreased hemoglobin content 2 | 68
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
enlarged heart 2 | 210
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased circulating sodium l... 2 | 71
increased or absent threshold ... 2 | 101
prolonged QT interval 2 | 38
abnormal QT variability 1 | 10
abnormal cecum morphology 1 | 7
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal thymus morphology 1 | 7
abnormal vibrissa morphology 1 | 25
brachydactyly 1 | 19
cataract 1 | 92
decreased body weight 1 | 161
decreased cardiac muscle contr... 1 | 11
decreased caudal vertebrae num... 1 | 53
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating lactate ... 1 | 3
decreased circulating sodium l... 1 | 22
decreased grip strength 1 | 116
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased large unstained cell... 1 | 11
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased circulating thyroxin... 1 | 7
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased startle reflex 1 | 112
microphthalmia 1 | 26
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged PQ interval 1 | 5
prolonged PR interval 1 | 15
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
small adrenal glands 1 | 16
small lymph nodes 1 | 1
small superior vagus ganglion 1 | 74
small thymus 1 | 16
stereotypic behavior 1 | 3
syndactyly 1 | 23
thrombocytosis 1 | 27
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 121 | 11,493
psoriasis 112 | 6,694
Cancer 105 | 2,499
diabetes mellitus 98 | 1,728
ovarian cancer 92 | 8,520
Ankylosing spondylitis 72 | 140
Rheumatoid arthritis 72 | 1,191
glioblastoma 71 | 5,792
Behcet's disease 70 | 89
Hypersensitivity reaction type II disease 70 | 253
osteosarcoma 70 | 7,950
Arthritis 69 | 290
tuberculosis 64 | 2,010
Juvenile rheumatoid arthritis 63 | 111
dermatomyositis 62 | 966
lung carcinoma 61 | 2,843
Human immunodeficiency virus infectious disease 58 | 138
Uveitis 58 | 103
lung cancer 58 | 4,740
Acquired immunodeficiency syndrome 56 | 197
Herpes zoster 56 | 68
medulloblastoma, large-cell 54 | 6,241
Psoriatic arthritis 53 | 86
Astrocytoma, Pilocytic 52 | 3,081
Stevens-Johnson syndrome 50 | 92
invasive ductal carcinoma 49 | 2,951
non-small cell lung cancer 44 | 2,890
ependymoma 42 | 4,679
subependymal giant cell astrocytoma 41 | 2,287
Dermatitis 40 | 157
Kidney disease 40 | 430
Multiple Sclerosis 39 | 540
intraductal papillary-mucinous adenoma (IPMA) 39 | 2,955
pancreatic cancer 38 | 2,398
Behcet's syndrome 36 | 50
Nephritis 36 | 51
Synovitis 36 | 78
adult high grade glioma 36 | 3,801
Breast cancer 35 | 3,578
Congenital adrenal hyperplasia 35 | 73
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,989
atypical teratoid / rhabdoid tumor 34 | 5,112
interstitial cystitis 33 | 2,312
malignant mesothelioma 32 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 32 | 1,962
Liver disease 31 | 237
lung adenocarcinoma 31 | 2,716
Anemia 30 | 365
breast carcinoma 30 | 1,638
juvenile dermatomyositis 29 | 1,187
colon cancer 28 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 28 | 3,291
Duchenne muscular dystrophy 27 | 601
ulcerative colitis 27 | 1,819
Hepatitis B 26 | 108
Leprosy 26 | 73
Multiple myeloma 25 | 1,332
cutaneous lupus erythematosus 25 | 1,057
group 3 medulloblastoma 25 | 4,104
astrocytoma 24 | 1,146
Hemochromatosis 23 | 54
Skin disease 23 | 66
adrenocortical carcinoma 22 | 1,428
cystic fibrosis 22 | 1,696
Birdshot chorioretinopathy 21 | 23
Primary immunodeficiency disease 21 | 54
Schizophrenia 21 | 1,160
Systemic lupus erythematosus 21 | 194
astrocytic glioma 21 | 2,597
oligodendroglioma 21 | 2,850
Kidney cancer 20 | 2,613
primary pancreatic ductal adenocarcinoma 20 | 1,109
primitive neuroectodermal tumor 20 | 3,035
Autosomal recessive predisposition 19 | 1,442
active Crohn's disease 19 | 922
primary Sjogren syndrome 19 | 735
sarcoidosis 19 | 370
mucosa-associated lymphoid tissue lymphoma 18 | 484
group 4 medulloblastoma 17 | 1,855
Narcolepsy 16 | 72
Pick disease 16 | 1,894
Waldenstrons macroglobulinemia 16 | 765
pediatric high grade glioma 16 | 1,064
Berylliosis 15 | 28
Bipolar Disorder 15 | 666
Human immunodeficiency virus type 1, susceptibility to 15 | 26
Pre-Eclampsia 15 | 68
acute quadriplegic myopathy 15 | 1,158
esophageal adenocarcinoma 15 | 737
head and neck cancer and chronic obstructive pulmonary disease 15 | 239
periodontitis 15 | 293
Becker muscular dystrophy 14 | 191
Liver Cirrhosis, Experimental 14 | 769
Multiple Sclerosis, Susceptibility to 14 | 15
Narcolepsy-cataplexy 14 | 21
gastric carcinoma 14 | 807

Tissue

Blood and immune system 142 | 16,909
Digestive Tract 141 | 17,369
Endocrine System 141 | 18,159
Female tissues 141 | 17,400
Skin and soft tissues 141 | 17,230
Liver and Pancreas 140 | 16,750
Respiratory system 140 | 16,393
Urinary Tract 140 | 16,678
Male tissues 139 | 17,142
Cardiovascular System 135 | 15,192
Nervous System 134 | 16,725

Target Family

Non-IDG 190 | 12,091
Enzyme 36 | 4,145
Kinase 2 | 634
Ion Channel 1 | 344

KEGG Pathway

Phagosome 229 | 229
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin beta-1 ITGB1 Tclin Non-IDG -3.15400 1269.8 1956
Actin, cytoplasmic 1 ACTB Tbio Non-IDG -3.52930 2830.7 1251
Integrin beta-3 ITGB3 Tclin Non-IDG -3.04475 986.9 1517
Calnexin CANX Tbio Non-IDG -2.87537 714.9 630
Transferrin receptor protein 1 TFRC Tbio Non-IDG -3.43851 2558.3 1677
Ras-related C3 botulinum toxin substrate 1 RAC1 Tbio Enzyme -1.94674 87.1 452