Development Level

Tbio 62 | 11,445
Tchem 14 | 1,598
Tdark 5 | 6,588
Tclin 2 | 613

IMPC Phenotype

decreased circulating choleste... 4 | 93
abnormal heart morphology 3 | 162
decreased circulating HDL chol... 3 | 68
decreased vertical activity 3 | 208
enlarged heart 3 | 210
abnormal behavior 2 | 298
abnormal lens morphology 2 | 81
decreased body weight 2 | 161
decreased caudal vertebrae num... 2 | 53
decreased circulating total pr... 2 | 49
decreased lean body mass 2 | 135
decreased total body fat amoun... 2 | 207
enlarged spleen 2 | 41
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal response to new envir... 1 | 10
abnormal response to tactile s... 1 | 17
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal tibia morphology 1 | 14
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
corneal opacity 1 | 32
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased heart rate variabili... 1 | 13
decreased heart weight 1 | 27
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 13
increased heart rate 1 | 23
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
long tibia 1 | 25
male infertility 1 | 123
microphthalmia 1 | 26
shortened RR interval 1 | 17
small epididymis 1 | 3
small seminal vesicle 1 | 10
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 54 | 11,493
ovarian cancer 46 | 8,520
psoriasis 38 | 6,694
pancreatic ductal adenocarcinoma liver metastasis 31 | 1,962
Autosomal recessive predisposition 29 | 1,442
Zellweger syndrome 29 | 37
osteosarcoma 29 | 7,950
medulloblastoma, large-cell 25 | 6,241
Muscle hypotonia 23 | 571
Seizures 23 | 596
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
Epilepsy 21 | 792
Failure to gain weight 21 | 365
Pediatric failure to thrive 21 | 365
Peroxisomal disease 21 | 22
glioblastoma 21 | 5,792
lung cancer 21 | 4,740
Hepatomegaly 20 | 285
Infantile Refsum disease 20 | 23
Short stature 20 | 531
malignant mesothelioma 20 | 3,232
Cataract 19 | 297
Cognitive delay 19 | 608
Global developmental delay 19 | 608
Mental and motor retardation 19 | 608
Nystagmus 19 | 317
atypical teratoid / rhabdoid tumor 19 | 5,112
Adrenoleukodystrophy 18 | 29
Cerebellar Ataxia 18 | 304
Concave bridge of nose 18 | 195
Depressed nasal bridge 18 | 195
Depressed nasal root/bridge 18 | 195
ependymoma 18 | 4,679
interstitial cystitis 18 | 2,312
Chondrodysplasia punctata 17 | 41
Lens Opacities 17 | 231
Low Vision 17 | 174
Muscle Spasticity 17 | 195
Retinitis Pigmentosa 17 | 226
Sensorineural Hearing Loss (disorder) 17 | 284
Visual Impairment 17 | 174
Abnormality of metabolism/homeostasis 16 | 134
Developmental regression 16 | 95
Difficulties with night vision 16 | 87
Hypoplastic mandible condyle 16 | 275
Liver diseases 16 | 87
Loss of developmental milestones 16 | 95
Mandibular hypoplasia 16 | 275
Mental deterioration in childhood 16 | 95
Micrognathism 16 | 275
Neurodevelopmental regression 16 | 95
Night Blindness 16 | 101
Psychomotor regression 16 | 95
Psychomotor regression beginning in infancy 16 | 95
Psychomotor regression in infants 16 | 95
Psychomotor regression, progressive 16 | 95
Small head 16 | 374
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
ulcerative colitis 16 | 1,819
Abnormal skeletal development 15 | 60
Abnormality of retinal pigmentation 15 | 111
Addison Disease 15 | 18
Adrenal cortical hypofunction 15 | 23
Anteverted nostril 15 | 191
Blepharoptosis 15 | 231
Broad flat nasal bridge 15 | 236
Byzanthine arch palate 15 | 194
Congenital Epicanthus 15 | 177
Elevated levels of phytanic acid 15 | 15
High forehead 15 | 102
Hydronephrosis 15 | 89
Hyperreflexia 15 | 209
Liver Failure 15 | 73
Long narrow head 15 | 75
Narrow cranium shape 15 | 75
Narrow head shape 15 | 75
Narrow skull shape 15 | 75
Nasal bridge wide 15 | 236
Optic Atrophy 15 | 242
Osteochondrodysplasias 15 | 72
Premature Birth 15 | 77
Respiratory Insufficiency 15 | 132
Respiratory function loss 15 | 121
Retinal pigment epithelial abnormality 15 | 111
Stippled epiphyses 15 | 28
Strabismus 15 | 270
Tall forehead 15 | 102
Turridolichocephaly 15 | 75
Upward slant of palpebral fissure 15 | 75
invasive ductal carcinoma 15 | 2,951
Death in early childhood 14 | 82
Electroencephalogram abnormal 14 | 101
Feeding difficulties in infancy 14 | 175
Flat face 14 | 52
Global developmental delay, severe 14 | 47
Icterus 14 | 82
Low-set, posteriorly rotated ears 14 | 110
Polymicrogyria 14 | 48
Severe psychomotor retardation 14 | 47
tuberculosis 14 | 2,010

Tissue

Liver and Pancreas 82 | 16,750
Urinary Tract 82 | 16,678
Blood and immune system 81 | 16,909
Digestive Tract 81 | 17,369
Endocrine System 81 | 18,159
Skin and soft tissues 81 | 17,230
Female tissues 80 | 17,400
Male tissues 79 | 17,142
Nervous System 79 | 16,725
Respiratory system 79 | 16,393
Cardiovascular System 75 | 15,192

Target Family

Enzyme 50 | 4,145
Non-IDG 26 | 12,091
Transporter 6 | 473
Kinase 1 | 634

KEGG Pathway

Peroxisome 83 | 83
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Catalase CAT Tbio Enzyme -3.63626 3427.5 629
Nitric oxide synthase, inducible NOS2 Tchem Enzyme -3.35134 2277.5 752
Superoxide dismutase [Cu-Zn] SOD1 Tbio Enzyme -3.30643 1972.1 1103
Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 Tchem Enzyme -3.19944 1567.0 498
Hydroxyacid oxidase 1 HAO1 Tchem Enzyme -3.03218 1057.3 229
Peroxiredoxin-5, mitochondrial PRDX5 Tbio Non-IDG -3.01329 950.2 285
Isocitrate dehydrogenase [NADP], mitochondrial IDH2 Tclin Enzyme -2.94039 813.3 296
Alkyldihydroxyacetonephosphate synthase, peroxisomal AGPS Tbio Enzyme -2.84508 679.5 84
Superoxide dismutase [Mn], mitochondrial SOD2 Tbio Enzyme -2.73272 470.1 697
Xanthine dehydrogenase/oxidase XDH Tclin Enzyme -2.69810 506.6 179