Development Level

Tbio 26 | 11,445
Tclin 14 | 613
Tchem 12 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 4 | 499
abnormal retina morphology 3 | 71
abnormal skin morphology 2 | 50
decreased circulating fructosa... 2 | 30
decreased circulating serum al... 2 | 82
edema 2 | 59
embryonic lethality prior to t... 2 | 278
increased neutrophil cell numb... 2 | 46
short tibia 2 | 97
abnormal bone mineralization 1 | 38
abnormal cecum morphology 1 | 7
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal hair texture 1 | 4
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal startle reflex 1 | 15
anophthalmia 1 | 33
decreased body weight 1 | 161
decreased circulating total pr... 1 | 49
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased lymphocyte cell numb... 1 | 83
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
fusion of vertebral arches 1 | 7
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased eosinophil cell numb... 1 | 11
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

Carcinoma 38 | 11,493
ovarian cancer 36 | 8,520
osteosarcoma 26 | 7,950
Cancer 24 | 2,499
psoriasis 23 | 6,694
atypical teratoid / rhabdoid tumor 21 | 5,112
glioblastoma 20 | 5,792
lung cancer 20 | 4,740
medulloblastoma, large-cell 20 | 6,241
pancreatic cancer 20 | 2,398
Breast cancer 18 | 3,578
ependymoma 16 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
non-small cell lung cancer 16 | 2,890
Astrocytoma, Pilocytic 15 | 3,081
Duchenne muscular dystrophy 12 | 601
breast carcinoma 12 | 1,638
juvenile dermatomyositis 12 | 1,187
malignant mesothelioma 12 | 3,232
tuberculosis 12 | 2,010
Multiple myeloma 11 | 1,332
Ocular hypertension 11 | 42
adult high grade glioma 11 | 3,801
diabetes mellitus 11 | 1,728
interstitial cystitis 11 | 2,312
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
lung carcinoma 11 | 2,843
primitive neuroectodermal tumor 11 | 3,035
Malignant tumor of prostate 10 | 26
Nephroblastoma 10 | 51
Open-angle glaucoma 10 | 27
group 4 medulloblastoma 10 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
primary pancreatic ductal adenocarcinoma 10 | 1,109
subependymal giant cell astrocytoma 10 | 2,287
Acute lymphoid leukemia 9 | 25
Anaplastic large T-cell systemic malignant lymphoma 9 | 10
Burkitt's lymphoma 9 | 15
Carcinoma of breast 9 | 11
Carcinoma of female breast 9 | 20
Diffuse non-Hodgkin's lymphoma, large cell 9 | 12
Follicular non-Hodgkin's lymphoma 9 | 17
Gestational trophoblastic neoplasia 9 | 14
HER2-positive carcinoma of breast 9 | 21
Hodgkin's disease 9 | 18
Hypertensive disorder 9 | 56
Kaposi's sarcoma 9 | 22
Langerhans cell histiocytosis, disseminated 9 | 10
Liposarcoma 9 | 20
Liver Cirrhosis, Experimental 9 | 769
Malignant tumor of head and/or neck 9 | 15
Malignant tumor of ovary 9 | 25
Malignant tumor of stomach 9 | 12
Malignant tumor of testis 9 | 11
Metastatic Breast Carcinoma 9 | 21
Metastatic Prostate Carcinoma 9 | 18
Mycosis fungoides 9 | 29
Neuroblastoma 9 | 80
Non-Hodgkin's lymphoma 9 | 22
Rhabdomyosarcoma 9 | 39
Rheumatoid arthritis 9 | 1,191
Schizophrenia 9 | 1,160
Secondary malignant neoplasm of pancreas 9 | 10
astrocytic glioma 9 | 2,597
astrocytoma 9 | 1,146
colon cancer 9 | 1,478
cystic fibrosis 9 | 1,696
oligodendroglioma 9 | 2,850
transitional cell carcinoma 9 | 22
ulcerative colitis 9 | 1,819
Kidney cancer 8 | 2,613
Lissencephaly 8 | 69
Animal Mammary Neoplasms 7 | 136
Breast Neoplasms 7 | 445
Down syndrome 7 | 499
Intellectual disability 7 | 1,016
Mammary Neoplasms 7 | 425
Mammary Neoplasms, Animal 7 | 136
Mammary Neoplasms, Experimental 7 | 154
Waldenstrons macroglobulinemia 7 | 765
adrenocortical carcinoma 7 | 1,428
dermatomyositis 7 | 966
gastric cancer 7 | 459
gastric carcinoma 7 | 807
group 3 medulloblastoma 7 | 4,104
mucosa-associated lymphoid tissue lymphoma 7 | 484
pancreatic carcinoma 7 | 562
Becker muscular dystrophy 6 | 191
Condyloma acuminatum 6 | 7
Kidney disease 6 | 430
Neoplasm Invasiveness 6 | 161
Neoplasm Metastasis 6 | 168
acute quadriplegic myopathy 6 | 1,158
ductal carcinoma in situ 6 | 1,745
hepatocellular carcinoma 6 | 547
pituitary cancer 6 | 1,972
primary Sjogren syndrome 5 | 735

Tissue

Endocrine System 53 | 18,159
Female tissues 53 | 17,400
Blood and immune system 52 | 16,909
Cardiovascular System 52 | 15,192
Digestive Tract 52 | 17,369
Male tissues 52 | 17,142
Nervous System 52 | 16,725
Skin and soft tissues 52 | 17,230
Urinary Tract 52 | 16,678
Liver and Pancreas 51 | 16,750
Respiratory system 50 | 16,393

Target Family

Non-IDG 47 | 12,091
Kinase 5 | 634
Enzyme 2 | 4,145

KEGG Pathway

Pathogenic Escherichia coli in... 54 | 54
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
Tubulin beta-6 chain TUBB6 Tclin Non-IDG -0.94163 8.01 85
Tubulin alpha-8 chain TUBA8 Tbio Non-IDG -0.87821 7.61 118
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.43493 235.4 358
Claudin-1 CLDN1 Tbio Non-IDG -2.07626 126.7 593
Keratin, type I cytoskeletal 18 KRT18 Tbio Non-IDG -3.05211 1057.8 1953
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Lymphocyte antigen 96 LY96 Tchem Non-IDG -2.77678 541.2 369
Cell division control protein 42 homolog CDC42 Tchem Enzyme -3.37283 2188.5 380