Development Level

Tbio 26 | 10,625
Tclin 14 | 602
Tchem 12 | 1,890
Tdark 2 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
abnormal retina morphology 2 | 100
decreased circulating fructosa... 2 | 31
hydrops fetalis 2 | 22
increased leukocyte cell numbe... 2 | 37
preweaning lethality, incomple... 2 | 260
abnormal bone mineralization 1 | 55
abnormal coat/hair pigmentatio... 1 | 54
abnormal hair texture 1 | 4
abnormal head morphology 1 | 10
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
decreased NK T cell number 1 | 28
decreased body weight 1 | 174
decreased circulating serum al... 1 | 79
decreased circulating total pr... 1 | 41
decreased hematocrit 1 | 25
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
fusion of vertebral arches 1 | 7
increased bone mineral density 1 | 52
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased red blood cell distr... 1 | 21
vertebral fusion 1 | 23

Disease

ovarian cancer 36 | 8,492
osteosarcoma 26 | 7,933
Cancer 23 | 2,346
psoriasis 23 | 6,685
glioblastoma 20 | 5,572
lung cancer 20 | 4,473
medulloblastoma, large-cell 20 | 6,234
pancreatic cancer 20 | 2,300
atypical teratoid / rhabdoid tumor 17 | 4,369
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
non-small cell lung cancer 16 | 2,798
Breast cancer 15 | 3,099
pilocytic astrocytoma 15 | 3,086
primary pancreatic ductal adenocarcinoma 14 | 1,271
Duchenne muscular dystrophy 12 | 602
juvenile dermatomyositis 12 | 1,189
Multiple myeloma 11 | 1,328
Ocular hypertension 11 | 27
diabetes mellitus 11 | 1,663
interstitial cystitis 11 | 2,299
invasive ductal carcinoma 11 | 2,950
lung adenocarcinoma 11 | 2,714
lung carcinoma 11 | 2,844
malignant mesothelioma 11 | 3,163
primitive neuroectodermal tumor 11 | 3,031
Malignant tumor of prostate 10 | 26
Nephroblastoma 10 | 45
breast carcinoma 10 | 1,614
subependymal giant cell astrocytoma 10 | 2,287
tuberculosis 10 | 1,563
ulcerative colitis 10 | 2,087
Acute lymphoid leukemia 9 | 25
Anaplastic large T-cell systemic malignant lymphoma 9 | 10
Burkitt's lymphoma 9 | 15
Carcinoma of breast 9 | 11
Carcinoma of female breast 9 | 20
Diffuse non-Hodgkin's lymphoma, large cell 9 | 12
Follicular non-Hodgkin's lymphoma 9 | 17
Gestational trophoblastic neoplasia 9 | 14
HER2-positive carcinoma of breast 9 | 10
Hodgkin's disease 9 | 18
Hypertensive disorder 9 | 58
Kaposi's sarcoma 9 | 20
Langerhans cell histiocytosis, disseminated 9 | 10
Liposarcoma 9 | 20
Malignant tumor of head and/or neck 9 | 15
Malignant tumor of ovary 9 | 25
Malignant tumor of stomach 9 | 12
Malignant tumor of testis 9 | 11
Metastatic Breast Carcinoma 9 | 21
Metastatic Prostate Carcinoma 9 | 18
Mycosis fungoides 9 | 30
Neuroblastoma 9 | 78
Non-Hodgkin's lymphoma 9 | 22
Open-angle glaucoma 9 | 26
Rhabdomyosarcoma 9 | 29
Rheumatoid Arthritis 9 | 1,171
Secondary malignant neoplasm of pancreas 9 | 10
astrocytic glioma 9 | 2,241
astrocytoma 9 | 1,493
colon cancer 9 | 1,475
cystic fibrosis 9 | 1,670
group 4 medulloblastoma 9 | 1,875
oligodendroglioma 9 | 2,849
transitional cell carcinoma 9 | 20
adult high grade glioma 8 | 2,148
pediatric high grade glioma 8 | 2,712
Animal Mammary Neoplasms 7 | 136
Carcinoma 7 | 2,147
Down syndrome 7 | 548
Mammary Neoplasms 7 | 410
Mammary Neoplasms, Experimental 7 | 150
Waldenstrons macroglobulinemia 7 | 765
adrenocortical carcinoma 7 | 1,427
dermatomyositis 7 | 967
ependymoma 7 | 2,514
gastric cancer 7 | 436
gastric carcinoma 7 | 832
medulloblastoma 7 | 1,524
mucosa-associated lymphoid tissue lymphoma 7 | 480
pancreatic carcinoma 7 | 567
Becker muscular dystrophy 6 | 187
Condyloma acuminatum 6 | 7
Lissencephaly 6 | 61
Neoplasm Invasiveness 6 | 127
acute quadriplegic myopathy 6 | 1,157
ductal carcinoma in situ 6 | 1,745
hepatocellular carcinoma 6 | 550
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
pituitary cancer 6 | 1,972
posterior fossa group B ependymoma 6 | 1,530
sonic hedgehog group medulloblastoma 6 | 1,482
Intellectual disability 5 | 573
Pick disease 5 | 1,893
Prostatic Neoplasms 5 | 471
cutaneous lupus erythematosus 5 | 1,056
esophageal adenocarcinoma 5 | 737
primary Sjogren syndrome 5 | 789

Tissue

Blood and immune system 54 | 17,995
Cardiovascular System 54 | 17,958
Digestive Tract 54 | 18,473
Endocrine System 54 | 18,512
Female tissues 54 | 18,647
Liver and Pancreas 54 | 18,136
Male tissues 54 | 17,969
Nervous System 54 | 18,561
Respiratory system 54 | 17,484
Urinary Tract 54 | 18,444
Skin and soft tissues 53 | 18,115

Target Family

Non-IDG 47 | 11,969
Kinase 5 | 634
Enzyme 2 | 4,146

KEGG Pathway

Pathogenic Escherichia coli in... 54 | 54
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tubulin beta-3 chain TUBB3 Tclin Non-IDG -2.04546 78.8 485
Wiskott-Aldrich syndrome protein WAS Tbio Non-IDG -3.08376 1138.7 279
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.59105 344.4 405
Claudin-1 CLDN1 Tbio Non-IDG -2.00753 111.2 472
Cytoplasmic protein NCK2 NCK2 Tbio Non-IDG -1.56739 34.8 215
Ezrin EZR Tbio Non-IDG -2.98006 942.2 903
Tubulin alpha-3C/D chain TUBA3C Tchem Non-IDG -1.52337 5.25 128
Tubulin alpha-8 chain TUBA8 Tbio Non-IDG -0.81285 6.27 102
14-3-3 protein theta YWHAQ Tchem Non-IDG -2.36422 217.4 316
Tubulin beta-6 chain TUBB6 Tclin Non-IDG -0.85558 6.79 66