Development Level

Tbio 13 | 11,651
Tchem 4 | 1,388
Tclin 1 | 612
Tdark 1 | 6,593

IMPC Phenotype

abnormal behavior 2 | 298
abnormal epididymis morphology 1 | 42
abnormal locomotor activation 1 | 16
abnormal stomach morphology 1 | 10
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating fructosa... 1 | 30
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased hematocrit 1 | 46
increased vertical activity 1 | 24
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 16 | 8,520
osteosarcoma 14 | 7,950
Carcinoma 13 | 11,493
ulcerative colitis 9 | 1,819
lung cancer 8 | 4,740
psoriasis 8 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung carcinoma 6 | 2,843
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
tuberculosis 5 | 2,010
Autosomal recessive predisposition 4 | 1,442
Pantothenate kinase-associated neurodegeneration 4 | 12
cystic fibrosis 4 | 1,696
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Breast cancer 3 | 3,578
Cystinosis 3 | 14
Dystonia 3 | 164
adult high grade glioma 3 | 3,801
ependymoma 3 | 4,679
malignant mesothelioma 3 | 3,232
nephrosclerosis 3 | 333
non-small cell lung cancer 3 | 2,890
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
Aceruloplasminemia 2 | 16
Astrocytoma, Pilocytic 2 | 3,081
Autistic Disorder 2 | 364
Bipolar Disorder 2 | 666
Citrullinemia 2 | 14
Delayed speech and language development 2 | 112
Dermatitis, Atopic 2 | 37
Dihydropyrimidine dehydrogenase deficiency 2 | 6
Dull intelligence 2 | 645
Endometriosis 2 | 540
Epilepsy 2 | 792
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Intellectual disability 2 | 1,016
Language Delay 2 | 112
Lethargy 2 | 77
Low intelligence 2 | 645
Malaria 2 | 160
Maple syrup urine disease 2 | 24
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Myopia 2 | 176
Neurodegeneration with brain iron accumulation 6 2 | 8
Neurodegenerative disease 2 | 414
Obesity 2 | 678
Optic Atrophy 2 | 242
Orotic aciduria 2 | 18
Phenotypic variability 2 | 150
Poor growth 2 | 114
Poor school performance 2 | 645
Reduced dihydropyrimidine dehydrogenase activity 2 | 2
Schizophrenia 2 | 1,160
Seizures 2 | 596
Speech Delay 2 | 112
Speech impairment 2 | 112
Very poor growth 2 | 114
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
astrocytic glioma 2 | 2,597
chronic lymphosyte leukemia 2 | 204
colon cancer 2 | 1,478
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
medulloblastoma, large-cell 2 | 6,241
mucosa-associated lymphoid tissue lymphoma 2 | 484
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
primary Sjogren syndrome 2 | 735
Abnormality of the cerebral vasculature 1 | 6
Autistic behavior 1 | 20
Bladder exstrophy 1 | 32
Central sleep apnea 1 | 11
Dyslipidemias 1 | 27
Hip joint varus deformity - observation 1 | 24
Linear atrophy 1 | 15
Lysinuric protein intolerance 1 | 15
Mild Mental Retardation 1 | 70
Morphological abnormality of the pyramidal tract 1 | 12
Neurodegeneration with brain iron accumulation 4 1 | 6
Neurodegenerative Diseases 1 | 38
Pneumothorax 1 | 23
Pyramidal tract disease 1 | 12
Stomatitis 1 | 21

Tissue

Blood and immune system 19 | 16,909
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Nervous System 18 | 16,725
Cardiovascular System 15 | 15,192

Target Family

Enzyme 13 | 4,145
Kinase 4 | 634
Non-IDG 2 | 12,091

KEGG Pathway

Pantothenate and CoA biosynthe... 19 | 19
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pantothenate kinase 2, mitochondrial PANK2 Tbio Kinase -2.24581 177.7 253
Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 Tchem Enzyme -1.88659 78.1 216
Acidic amino acid decarboxylase GADL1 GADL1 Tbio Enzyme -1.55798 36.2 79
Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 Tchem Enzyme -1.82669 64.7 170
Pantothenate kinase 3 PANK3 Tchem Kinase -1.07308 10.3 167
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 ENPP3 Tbio Enzyme -2.63069 396.7 315
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 ENPP1 Tchem Enzyme -2.74480 552.8 275
Pantothenate kinase 4 PANK4 Tdark Kinase -0.46453 3.01 101
Vascular non-inflammatory molecule 3 VNN3 Tbio Non-IDG -0.70530 5.66 70
Dihydropyrimidine dehydrogenase [NADP(+)] DPYD Tclin Enzyme -2.62432 395.0 159