Development Level

Tbio 46 | 11,445
Tchem 29 | 1,598
Tclin 21 | 613
Tdark 3 | 6,588

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
increased startle reflex 5 | 112
preweaning lethality, complete... 5 | 979
abnormal bone structure 4 | 187
increased heart weight 4 | 62
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
cataract 3 | 92
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
abnormal seminal vesicle morph... 2 | 114
abnormal vocalization 2 | 21
decreased circulating chloride... 2 | 30
decreased circulating sodium l... 2 | 22
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
hydrometra 2 | 53
hyperactivity 2 | 148
small superior vagus ganglion 2 | 74
abnormal embryo turning 1 | 31
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal gallbladder morpholog... 1 | 1
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal sensory capabilities-... 1 | 8
abnormal sleep behavior 1 | 70
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
edema 1 | 59
enlarged epididymis 1 | 31
enlarged gallbladder 1 | 2
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
small epididymis 1 | 3

Disease

Carcinoma 65 | 11,493
ovarian cancer 47 | 8,520
psoriasis 47 | 6,694
medulloblastoma, large-cell 41 | 6,241
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,291
lung cancer 37 | 4,740
glioblastoma 36 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,989
atypical teratoid / rhabdoid tumor 34 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 33 | 2,955
osteosarcoma 31 | 7,950
adult high grade glioma 30 | 3,801
pancreatic cancer 30 | 2,398
Kidney cancer 29 | 2,613
ependymoma 29 | 4,679
lung carcinoma 28 | 2,843
lung adenocarcinoma 26 | 2,716
Breast cancer 25 | 3,578
cystic fibrosis 24 | 1,696
Astrocytoma, Pilocytic 23 | 3,081
non-small cell lung cancer 23 | 2,890
astrocytic glioma 22 | 2,597
group 3 medulloblastoma 22 | 4,104
primitive neuroectodermal tumor 22 | 3,035
Cancer 21 | 2,499
oligodendroglioma 21 | 2,850
interstitial cystitis 20 | 2,312
invasive ductal carcinoma 20 | 2,951
diabetes mellitus 19 | 1,728
malignant mesothelioma 19 | 3,232
pituitary cancer 19 | 1,972
colon cancer 17 | 1,478
Autosomal recessive predisposition 16 | 1,442
Pick disease 16 | 1,894
subependymal giant cell astrocytoma 16 | 2,287
Bipolar Disorder 15 | 666
Epilepsy 14 | 792
tuberculosis 14 | 2,010
ulcerative colitis 14 | 1,819
Hypertension 13 | 396
Liver cancer 12 | 604
Obesity 12 | 678
group 4 medulloblastoma 12 | 1,855
Pancreatitis 11 | 123
Melanoma 10 | 711
Schizophrenia 10 | 1,160
ductal carcinoma in situ 10 | 1,745
primary pancreatic ductal adenocarcinoma 10 | 1,109
Atrial Fibrillation 9 | 124
Chronic heart failure 9 | 46
Congestive heart failure 9 | 113
Depressive disorder 9 | 409
Hypertensive disease 9 | 292
Skin cancer 9 | 469
Adenoma 8 | 167
Duchenne muscular dystrophy 8 | 601
Exocrine pancreatic insufficiency 8 | 32
Poisoning by digitalis glycoside 8 | 8
astrocytoma 8 | 1,146
cutaneous lupus erythematosus 8 | 1,057
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Asthma 7 | 385
Coronary artery disease 7 | 268
Failure to gain weight 7 | 365
Intellectual disability 7 | 1,016
Multiple myeloma 7 | 1,332
Neurodegenerative disease 7 | 414
Parkinson's disease 7 | 392
Pediatric failure to thrive 7 | 365
Waldenstrons macroglobulinemia 7 | 765
active ulcerative colitis 7 | 764
gastric carcinoma 7 | 807
progressive supranuclear palsy 7 | 676
Atherosclerosis 6 | 291
Cardiomegaly 6 | 116
Diabetes Mellitus, Non-Insulin-Dependent 6 | 145
Dull intelligence 6 | 645
Low intelligence 6 | 645
Major Depressive Disorder 6 | 301
Mental Depression 6 | 333
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Mood Disorders 6 | 184
Osteoporosis 6 | 363
Poor school performance 6 | 645
Rheumatoid arthritis 6 | 1,191
Seizures 6 | 596
Substance Withdrawal Syndrome 6 | 55
Unipolar Depression 6 | 250
active Crohn's disease 6 | 922
adrenocortical carcinoma 6 | 1,428
esophageal adenocarcinoma 6 | 737
head and neck cancer 6 | 271
mucosa-associated lymphoid tissue lymphoma 6 | 484
Diabetes Mellitus, Type 2 5 | 142
Glaucoma 5 | 239
Heart disease 5 | 306
Kidney disease 5 | 430
chronic rhinosinusitis 5 | 512
spina bifida 5 | 1,074

Tissue

Digestive Tract 95 | 17,369
Endocrine System 93 | 18,159
Liver and Pancreas 92 | 16,750
Skin and soft tissues 92 | 17,230
Blood and immune system 91 | 16,909
Female tissues 91 | 17,400
Male tissues 91 | 17,142
Nervous System 89 | 16,725
Urinary Tract 89 | 16,678
Respiratory system 84 | 16,393
Cardiovascular System 80 | 15,192

Target Family

Enzyme 56 | 4,145
Transporter 20 | 473
Ion Channel 12 | 344
Non-IDG 5 | 12,091
GPCR 3 | 408
Kinase 3 | 634

KEGG Pathway

Pancreatic secretion 99 | 99
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Electrogenic sodium bicarbonate cotransporter 1 SLC4A4 Tbio Transporter -2.63743 436.2 124
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Ras-related protein Rab-3D RAB3D Tbio Enzyme -2.56190 342.2 106
Mast cell carboxypeptidase A CPA3 Tchem Enzyme -1.72972 50.2 151
Carboxypeptidase B CPB1 Tchem Enzyme -2.97696 883.0 228
Carboxypeptidase A1 CPA1 Tchem Enzyme -1.95541 84.1 265
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Sodium/potassium-transporting ATPase subunit gamma FXYD2 Tclin Enzyme -1.58017 39.0 64