Development Level

Tbio 62 | 10,625
Tclin 48 | 602
Tdark 15 | 7,003
Tchem 8 | 1,890

IMPC Term

preweaning lethality, complete... 20 | 633
embryonic lethality prior to o... 12 | 148
embryonic lethality prior to t... 9 | 187
abnormal embryo size 3 | 112
abnormal lens morphology 3 | 73
hypoactivity 3 | 89
increased fasted circulating g... 3 | 68
pallor 3 | 13
abnormal behavior 2 | 226
abnormal kidney morphology 2 | 30
abnormal skin coloration 2 | 18
decreased caudal vertebrae num... 2 | 49
decreased erythrocyte cell num... 2 | 43
decreased mean corpuscular vol... 2 | 50
decreased mean platelet volume 2 | 12
decreased total retina thickne... 2 | 20
embryonic growth retardation 2 | 28
prenatal lethality prior to he... 2 | 64
abnormal QRS complex 1 | 25
abnormal embryo turning 1 | 15
abnormal foot plate morphology 1 | 2
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal limb bud morphology 1 | 15
abnormal liver size 1 | 4
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placenta development 1 | 1
abnormal placenta morphology 1 | 4
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal seminal vesicle morph... 1 | 47
abnormal skin appearance 1 | 8
abnormal tail movements 1 | 12
abnormal visceral yolk sac mor... 1 | 2
cardiovascular system phenotyp... 1 | 35
decreased blood urea nitrogen ... 1 | 31
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased hemoglobin content 1 | 53
decreased lactate dehydrogenas... 1 | 14
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
enlarged heart atrium 1 | 2
hyperactivity 1 | 108
increased CD4-positive, CD25-p... 1 | 18
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased bone mineral content 1 | 92
increased circulating free fat... 1 | 17
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased startle reflex 1 | 38
pale liver 1 | 5
prenatal lethality 1 | 16
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
small adrenal glands 1 | 15
small lymph nodes 1 | 1
thrombocytosis 1 | 23

Disease

ovarian cancer 72 | 8,484
Multiple myeloma 53 | 1,327
Diabetes mellitus type 2 46 | 69
Treatment Refractory Type 2 Diabetes Mellitus 46 | 53
osteosarcoma 38 | 7,933
psoriasis 34 | 6,685
Leigh disease 33 | 81
lung cancer 29 | 4,466
glioblastoma 25 | 5,572
medulloblastoma, large-cell 24 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
MITOCHONDRIAL COMPLEX I DEFICIENCY 22 | 37
astrocytic glioma 22 | 2,241
atypical teratoid / rhabdoid tumor 21 | 4,369
ependymoma 21 | 2,514
oligodendroglioma 19 | 2,849
Waldenstrons macroglobulinemia 17 | 765
Breast cancer 15 | 3,094
astrocytoma 15 | 1,493
Pick disease 14 | 1,893
NADH:Q(1) Oxidoreductase deficiency 13 | 20
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
medulloblastoma 13 | 1,524
Leber hereditary optic neuropathy 12 | 17
diabetes mellitus 12 | 1,663
LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY 11 | 14
Mitochondrial myopathy 11 | 23
primitive neuroectodermal tumor 11 | 3,031
Optic Atrophy, Hereditary, Leber 10 | 14
adult high grade glioma 10 | 2,148
non primary Sjogren syndrome sicca 10 | 840
lung carcinoma 9 | 2,844
subependymal giant cell astrocytoma 9 | 2,287
Parkinson's disease 8 | 364
Pneumonia 8 | 133
pediatric high grade glioma 8 | 2,712
Osteopetrosis 7 | 40
breast carcinoma 7 | 1,614
pilocytic astrocytoma 7 | 3,086
Cancer 6 | 2,346
Lactic acidosis 6 | 42
MELAS syndrome 6 | 17
acute myeloid leukemia 6 | 780
cytochrome-c oxidase deficiency disease 6 | 14
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
pituitary cancer 6 | 1,972
tuberculosis and treatment for 6 months 6 | 686
Alzheimer's disease 5 | 644
Anemia 5 | 252
Cytochrome-c Oxidase Deficiency 5 | 15
Down syndrome 5 | 548
Polycystic Ovary Syndrome 5 | 332
colon cancer 5 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
lung adenocarcinoma 5 | 2,713
malignant mesothelioma 5 | 3,162
non-small cell lung cancer 5 | 2,798
ulcerative colitis 5 | 2,087
3-methylglutaconic aciduria 4 | 29
Degenerative polyarthritis 4 | 93
Gastrointestinal stromal tumor 4 | 61
LEBER OPTIC ATROPHY AND DYSTONIA 4 | 4
Malaria 4 | 140
Neoplastic Syndromes, Hereditary 4 | 48
Neuropathy 4 | 210
Obesity 4 | 616
Optic atrophy 4 | 43
Persistent generalized lymphadenopathy 4 | 15
Phaeochromocytoma 4 | 20
Retinitis pigmentosa 4 | 153
Stomach Neoplasms 4 | 282
cystic fibrosis 4 | 1,665
dermatomyositis 4 | 933
group 3 medulloblastoma 4 | 2,254
invasive ductal carcinoma 4 | 2,950
sonic hedgehog group medulloblastoma 4 | 1,482
tuberculosis 4 | 1,557
Cardiomyopathies 3 | 90
Cardiomyopathy 3 | 110
Cerebrovascular disease 3 | 231
Chagas disease 3 | 34
Cutis laxa 3 | 28
Disease Progression 3 | 125
Dystonia 3 | 77
Gastroesophageal reflux disease 3 | 37
Gastrointestinal Stromal Tumors 3 | 8
Hypersensitivity reaction type II disease 3 | 235
Kidney disease 3 | 396
Metabolic acidosis 3 | 49
Mitochondrial Encephalomyopathies 3 | 11
Muscle Weakness 3 | 92
Neurodegenerative disease 3 | 383
Neuronal ceroid lipofuscinosis 3 | 28
Osteoporosis 3 | 257
Schizophrenia 3 | 501
Wolff-Parkinson-White syndrome 3 | 11
acute quadriplegic myopathy 3 | 1,157
aldosterone-producing adenoma 3 | 664
hereditary spastic paraplegia 3 | 313
pancreatic cancer 3 | 2,300

Tissue

Cardiovascular System 133 | 17,958
Nervous System 133 | 18,561
Urinary Tract 133 | 18,444
Blood and immune system 132 | 17,995
Digestive Tract 132 | 18,473
Endocrine System 132 | 18,512
Female tissues 132 | 18,647
Liver and Pancreas 132 | 18,136
Male tissues 132 | 17,969
Skin and soft tissues 132 | 18,115
Respiratory system 131 | 17,484

Target Family

Enzyme 120 | 4,146
Non-IDG 10 | 11,971
Transporter 3 | 473

KEGG Pathway

Oxidative phosphorylation 133 | 133
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP synthase F(0) complex subunit C3, mitochondrial ATP5G3 Tdark Enzyme -1.10871 11.9 27
NADH-ubiquinone oxidoreductase chain 6 MT-ND6 Tclin Enzyme -2.74395 585.6 62
ATP synthase protein 8 MT-ATP8 Tbio Enzyme -2.30895 191.4 20
V-type proton ATPase catalytic subunit A ATP6V1A Tbio Enzyme -1.80191 64.7 120
Cytochrome c oxidase subunit 6A1, mitochondrial COX6A1 Tbio Enzyme -1.00384 11.8 165
Cytochrome c oxidase subunit 7C, mitochondrial COX7C Tdark Enzyme -0.99133 9.67 34
Cytochrome b MT-CYB Tbio Non-IDG -3.74473 5676.0 122
Potassium-transporting ATPase subunit beta ATP4B Tclin Transporter -0.76953 6.01 159
V-type proton ATPase 116 kDa subunit a isoform 1 ATP6V0A1 Tbio Enzyme -1.36455 23.7 59
ATP synthase F(0) complex subunit B1, mitochondrial ATP5F1 Tbio Enzyme -0.80065 5.85 92