Development Level

Tbio 62 | 10,625
Tclin 48 | 602
Tdark 15 | 7,003
Tchem 8 | 1,890

IMPC Phenotype

preweaning lethality, complete... 20 | 633
embryonic lethality prior to o... 12 | 148
embryonic lethality prior to t... 9 | 187
abnormal embryo size 3 | 112
abnormal lens morphology 3 | 73
hypoactivity 3 | 89
increased fasted circulating g... 3 | 68
pallor 3 | 13
abnormal behavior 2 | 226
abnormal kidney morphology 2 | 30
abnormal skin coloration 2 | 18
decreased caudal vertebrae num... 2 | 49
decreased erythrocyte cell num... 2 | 43
decreased mean corpuscular vol... 2 | 50
decreased mean platelet volume 2 | 12
decreased total retina thickne... 2 | 20
embryonic growth retardation 2 | 28
prenatal lethality prior to he... 2 | 64
abnormal QRS complex 1 | 25
abnormal embryo turning 1 | 15
abnormal foot plate morphology 1 | 2
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal limb bud morphology 1 | 15
abnormal liver size 1 | 4
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placenta development 1 | 1
abnormal placenta morphology 1 | 4
abnormal placenta size 1 | 10
abnormal retina morphology 1 | 100
abnormal seminal vesicle morph... 1 | 47
abnormal skin appearance 1 | 8
abnormal tail movements 1 | 12
abnormal visceral yolk sac mor... 1 | 2
cardiovascular system phenotyp... 1 | 35
decreased blood urea nitrogen ... 1 | 31
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased hemoglobin content 1 | 53
decreased lactate dehydrogenas... 1 | 14
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased prepulse inhibition 1 | 52
decreased startle reflex 1 | 48
decreased total body fat amoun... 1 | 186
enlarged heart atrium 1 | 2
hyperactivity 1 | 108
increased CD4-positive, CD25-p... 1 | 18
increased T cell number 1 | 15
increased alpha-beta T cell nu... 1 | 9
increased bone mineral content 1 | 92
increased circulating free fat... 1 | 17
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased heart weight 1 | 37
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased startle reflex 1 | 38
pale liver 1 | 5
prenatal lethality 1 | 16
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
small adrenal glands 1 | 15
small lymph nodes 1 | 1
thrombocytosis 1 | 23

Disease

ovarian cancer 73 | 8,491
Multiple myeloma 53 | 1,327
Diabetes mellitus type 2 46 | 69
Treatment Refractory Type 2 Diabetes Mellitus 46 | 53
osteosarcoma 38 | 7,933
psoriasis 34 | 6,685
Leigh disease 33 | 81
lung cancer 29 | 4,473
glioblastoma 25 | 5,572
medulloblastoma, large-cell 24 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,795
Mitochondrial complex I deficiency 22 | 37
astrocytic glioma 22 | 2,241
Leigh syndrome 21 | 34
atypical teratoid / rhabdoid tumor 21 | 4,369
ependymoma 21 | 2,514
Mitochondrial Complex 1 Deficiency 19 | 28
oligodendroglioma 19 | 2,849
Waldenstrons macroglobulinemia 17 | 764
Breast cancer 15 | 3,098
astrocytoma 15 | 1,493
Pick disease 14 | 1,893
NADH:Q(1) Oxidoreductase deficiency 13 | 20
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
medulloblastoma 13 | 1,524
Leber hereditary optic neuropathy 12 | 17
diabetes mellitus 12 | 1,663
LEIGH SYNDROME DUE TO MITOCHONDRIAL COMPLEX I DEFICIENCY 11 | 14
Mitochondrial myopathy 11 | 24
primitive neuroectodermal tumor 11 | 3,031
Leber's optic atrophy 10 | 10
Optic Atrophy, Hereditary, Leber 10 | 14
adult high grade glioma 10 | 2,148
non primary Sjogren syndrome sicca 10 | 840
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes 9 | 9
lung carcinoma 9 | 2,844
subependymal giant cell astrocytoma 9 | 2,287
Parkinson's disease 8 | 364
Pneumonia 8 | 133
pediatric high grade glioma 8 | 2,712
Osteopetrosis 7 | 40
breast carcinoma 7 | 1,614
cytochrome-c oxidase deficiency disease 7 | 19
pilocytic astrocytoma 7 | 3,086
Cancer 6 | 2,346
Lactic acidosis 6 | 43
MELAS syndrome 6 | 17
acute myeloid leukemia 6 | 785
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
pituitary cancer 6 | 1,972
tuberculosis and treatment for 6 months 6 | 686
Alzheimer's disease 5 | 644
Anemia 5 | 252
Cytochrome-c Oxidase Deficiency 5 | 15
Down syndrome 5 | 548
Mitochondrial complex IV deficiency 5 | 6
Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome 5 | 5
Polycystic Ovary Syndrome 5 | 334
colon cancer 5 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
lung adenocarcinoma 5 | 2,714
malignant mesothelioma 5 | 3,163
non-small cell lung cancer 5 | 2,798
ulcerative colitis 5 | 2,087
3-methylglutaconic aciduria 4 | 29
Degenerative polyarthritis 4 | 93
Gastrointestinal stromal tumor 4 | 61
LEBER OPTIC ATROPHY AND DYSTONIA 4 | 4
Malaria 4 | 140
Neoplastic Syndromes, Hereditary 4 | 48
Neuropathy 4 | 210
Obesity 4 | 616
Optic atrophy 4 | 43
Persistent generalized lymphadenopathy 4 | 15
Phaeochromocytoma 4 | 20
Retinitis pigmentosa 4 | 156
Stomach Neoplasms 4 | 282
cystic fibrosis 4 | 1,670
dermatomyositis 4 | 966
group 3 medulloblastoma 4 | 2,254
invasive ductal carcinoma 4 | 2,950
sonic hedgehog group medulloblastoma 4 | 1,482
tuberculosis 4 | 1,563
Cardiomyopathies 3 | 90
Cerebrovascular disease 3 | 231
Chagas disease 3 | 34
Cutis laxa 3 | 28
Disease Progression 3 | 125
Gastroesophageal reflux disease 3 | 37
Hypersensitivity reaction type II disease 3 | 235
Kidney disease 3 | 397
Mitochondrial Encephalomyopathies 3 | 11
Muscle Weakness 3 | 92
Neurodegenerative disease 3 | 383
Osteoporosis 3 | 259
Wolff-Parkinson-White syndrome 3 | 11
acute quadriplegic myopathy 3 | 1,157
aldosterone-producing adenoma 3 | 664
hereditary spastic paraplegia 3 | 313
pancreatic cancer 3 | 2,300

Tissue

Cardiovascular System 133 | 17,957
Nervous System 133 | 18,560
Urinary Tract 133 | 18,443
Blood and immune system 132 | 17,994
Digestive Tract 132 | 18,472
Endocrine System 132 | 18,511
Female tissues 132 | 18,646
Liver and Pancreas 132 | 18,135
Male tissues 132 | 17,968
Skin and soft tissues 132 | 18,114
Respiratory system 131 | 17,483

Target Family

Enzyme 120 | 4,146
Non-IDG 10 | 11,969
Transporter 3 | 473

KEGG Pathway

Oxidative phosphorylation 133 | 133
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..