Development Level

Tbio 22 | 11,445
Tchem 18 | 1,598
Tclin 10 | 613
Tdark 2 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal bone structure 5 | 187
improved glucose tolerance 4 | 79
increased heart weight 4 | 62
increased startle reflex 4 | 112
abnormal behavior 3 | 298
increased circulating choleste... 3 | 66
abnormal male genitalia morpho... 2 | 3
decreased bone mineral content 2 | 151
decreased circulating chloride... 2 | 30
decreased grip strength 2 | 116
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
absent startle reflex 1 | 24
cardiovascular system phenotyp... 1 | 36
decreased bone mineral density 1 | 126
decreased brain size 1 | 4
decreased cardiac muscle contr... 1 | 11
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating unsatura... 1 | 2
decreased exploration in new e... 1 | 11
decreased heart rate 1 | 18
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
enlarged heart 1 | 210
enlarged spleen 1 | 41
fusion of vertebral arches 1 | 7
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
oligodactyly 1 | 1
polydactyly 1 | 7
polysyndactyly 1 | 2
preweaning lethality, incomple... 1 | 499
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small thymus 1 | 16
vertebral transformation 1 | 12

Disease

Carcinoma 39 | 11,493
ovarian cancer 27 | 8,520
psoriasis 25 | 6,694
Polycystic ovary syndrome 20 | 360
medulloblastoma, large-cell 20 | 6,241
atypical teratoid / rhabdoid tumor 19 | 5,112
Kidney cancer 17 | 2,613
glioblastoma 17 | 5,792
lung cancer 17 | 4,740
osteosarcoma 17 | 7,950
Breast cancer 16 | 3,578
Cancer 16 | 2,499
interstitial cystitis 16 | 2,312
pancreatic cancer 15 | 2,398
Autosomal recessive predisposition 14 | 1,442
Obesity 14 | 678
ependymoma 14 | 4,679
lung carcinoma 14 | 2,843
Infertility 13 | 188
diabetes mellitus 13 | 1,728
Hypogonadism 12 | 173
Prostatic Neoplasms 12 | 495
adult high grade glioma 12 | 3,801
oligodendroglioma 12 | 2,850
pituitary cancer 12 | 1,972
Adenoma 11 | 167
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
invasive ductal carcinoma 11 | 2,951
lung adenocarcinoma 11 | 2,716
Alzheimer's disease 10 | 658
Anovulation 10 | 21
Cushing's syndrome 10 | 48
Delayed bone age 10 | 136
Hyperandrogenism 10 | 34
Hypertensive disease 10 | 292
Osteoporosis 10 | 363
astrocytic glioma 10 | 2,597
cystic fibrosis 10 | 1,696
ductal carcinoma in situ 10 | 1,745
malignant mesothelioma 10 | 3,232
non-small cell lung cancer 10 | 2,890
Amenorrhea 9 | 58
Endometriosis 9 | 540
Hypertension 9 | 396
adrenocortical carcinoma 9 | 1,428
group 3 medulloblastoma 9 | 4,104
group 4 medulloblastoma 9 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
primitive neuroectodermal tumor 9 | 3,035
ulcerative colitis 9 | 1,819
Astrocytoma, Pilocytic 8 | 3,081
Bipolar Disorder 8 | 666
Breast Neoplasms 8 | 445
Male infertility 8 | 206
Mammary Neoplasms 8 | 425
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Acromegaly 7 | 51
Congenital adrenal hyperplasia 7 | 73
Delayed Puberty 7 | 97
Depressive disorder 7 | 409
Hypothyroidism 7 | 122
Kidney disease 7 | 430
Liver Cirrhosis, Experimental 7 | 769
Liver cancer 7 | 604
Premature ovarian failure 7 | 65
Schizophrenia 7 | 1,160
Short stature 7 | 531
Acquired metabolic disease 6 | 336
Atherosclerosis 6 | 291
Carney complex 6 | 25
Generalized osteopenia 6 | 99
Gynecomastia 6 | 64
Hyperthyroidism 6 | 53
Insulin Resistance 6 | 72
McCune Albright syndrome 6 | 19
Osteopenia 6 | 99
Pituitary adenoma 6 | 38
Precocious Puberty 6 | 28
Primary pigmented nodular adrenocortical disease 6 | 13
Substance Withdrawal Syndrome 6 | 55
astrocytoma 6 | 1,146
spina bifida 6 | 1,074
subependymal giant cell astrocytoma 6 | 2,287
Carcinoma, Hepatocellular 5 | 228
Coronary artery disease 5 | 268
Infertility, Male 5 | 46
Liver carcinoma 5 | 240
Mental Depression 5 | 333
Pick disease 5 | 1,894
Rheumatoid arthritis 5 | 1,191
aldosterone-producing adenoma 5 | 665
medulloblastoma 5 | 720
pancreatic carcinoma 5 | 562
pediatric high grade glioma 5 | 1,064
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
substance-related disorder 5 | 162

Tissue

Endocrine System 48 | 18,159
Female tissues 47 | 17,400
Digestive Tract 45 | 17,369
Skin and soft tissues 45 | 17,230
Liver and Pancreas 44 | 16,750
Blood and immune system 43 | 16,909
Nervous System 43 | 16,725
Urinary Tract 43 | 16,678
Male tissues 42 | 17,142
Respiratory system 42 | 16,393
Cardiovascular System 38 | 15,192

Target Family

Enzyme 27 | 4,145
Non-IDG 18 | 12,091
Kinase 5 | 634
GPCR 2 | 408

KEGG Pathway

Ovarian steroidogenesis 52 | 52
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 HSD3B1 Tchem Enzyme -2.62147 370.7 267
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Cytosolic phospholipase A2 gamma PLA2G4C Tchem Enzyme -1.27690 20.9 63
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Adenylate cyclase type 6 ADCY6 Tchem Enzyme -2.05332 113.7 111
Cytosolic phospholipase A2 delta PLA2G4D Tbio Enzyme -0.54284 3.41 45
Glycoprotein hormones alpha chain CGA Tbio Non-IDG -2.62079 405.6 915
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.61657 45.3 134
Bone morphogenetic protein 6 BMP6 Tbio Non-IDG -2.55269 373.2 317