Development Level

Tbio 30 | 11,445
Tchem 14 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
decreased vertical activity 2 | 208
increased grip strength 2 | 41
abnormal behavior 1 | 298
abnormal eating behavior 1 | 1
abnormal embryo size 1 | 220
abnormal forced expiratory flo... 1 | 1
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal tail morphology 1 | 25
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
cyanosis 1 | 7
decreased basophil cell number 1 | 16
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased tidal volume 1 | 1
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged kidney 1 | 14
hemorrhage 1 | 23
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating glycerol... 1 | 9
increased circulating iron lev... 1 | 30
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
pale yolk sac 1 | 25
pallor 1 | 34
preweaning lethality, incomple... 1 | 499
respiratory system phenotype 1 | 2
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 36 | 11,493
ovarian cancer 27 | 8,520
Cancer 24 | 2,499
osteosarcoma 24 | 7,950
psoriasis 23 | 6,694
medulloblastoma, large-cell 20 | 6,241
glioblastoma 19 | 5,792
lung cancer 16 | 4,740
group 3 medulloblastoma 15 | 4,104
oligodendroglioma 15 | 2,850
ependymoma 14 | 4,679
Astrocytoma, Pilocytic 13 | 3,081
Breast cancer 13 | 3,578
atypical teratoid / rhabdoid tumor 13 | 5,112
Breast Neoplasms 11 | 445
Mammary Neoplasms 11 | 425
adult high grade glioma 11 | 3,801
astrocytic glioma 11 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Alzheimer's disease 10 | 658
Schizophrenia 10 | 1,160
astrocytoma 10 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
malignant mesothelioma 10 | 3,232
primitive neuroectodermal tumor 10 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
pediatric high grade glioma 9 | 1,064
Carcinoma, Pancreatic Ductal 8 | 20
Carcinoma, Squamous Cell 8 | 110
Failure to gain weight 8 | 365
Pediatric failure to thrive 8 | 365
invasive ductal carcinoma 8 | 2,951
juvenile dermatomyositis 8 | 1,187
subependymal giant cell astrocytoma 8 | 2,287
Acquired scoliosis 7 | 281
Curvature of spine 7 | 282
Kidney cancer 7 | 2,613
Rheumatoid arthritis 7 | 1,191
Short stature 7 | 531
Strabismus 7 | 270
lung adenocarcinoma 7 | 2,716
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
Adenoid Cystic Carcinoma 6 | 99
Alagille syndrome 6 | 15
Brachydactyly 6 | 156
Carcinoma, Adenoid Cystic 6 | 99
Cataract 6 | 297
Cryptorchidism 6 | 296
Hypoplastic mandible condyle 6 | 275
Lens Opacities 6 | 231
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Short distal phalanges 6 | 50
group 4 medulloblastoma 6 | 1,855
interstitial cystitis 6 | 2,312
pituitary cancer 6 | 1,972
tuberculosis 6 | 2,010
Bipolar Disorder 5 | 666
Cerebrovascular disease 5 | 238
Dementia 5 | 175
Downward slant of palpebral fissure 5 | 158
Epilepsy 5 | 792
Esophageal Squamous Cell Carcinoma 5 | 77
Exophthalmos 5 | 112
Immune system cancer 5 | 140
Liver cancer 5 | 604
Lymphoid leukemia 5 | 160
Multiple Sclerosis 5 | 540
Multiple myeloma 5 | 1,332
Orbital separation excessive 5 | 244
Prominent eyes 5 | 96
Prominent globes 5 | 96
Protruding eyes 5 | 96
Seizures 5 | 596
Squamous cell carcinoma of esophagus 5 | 77
Syndactyly 5 | 88
Ventricular Septal Defects 5 | 119
primary pancreatic ductal adenocarcinoma 5 | 1,109
ulcerative colitis 5 | 1,819
Broad flat nasal bridge 4 | 236
Byzanthine arch palate 4 | 194
Congenital Epicanthus 4 | 177
Delayed bone age 4 | 136
Down syndrome 4 | 499
Liver Cirrhosis 4 | 181
Lung Neoplasms 4 | 232
Nasal bridge wide 4 | 236
Neurodegenerative disease 4 | 414
Pectus excavatum 4 | 100
Pick disease 4 | 1,894
aldosterone-producing adenoma 4 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
breast carcinoma 4 | 1,638
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 807
pancreatic cancer 4 | 2,398
spina bifida 4 | 1,074

Tissue

Digestive Tract 48 | 17,369
Endocrine System 48 | 18,159
Blood and immune system 47 | 16,909
Liver and Pancreas 47 | 16,750
Skin and soft tissues 47 | 17,230
Female tissues 46 | 17,400
Male tissues 46 | 17,142
Nervous System 46 | 16,725
Respiratory system 46 | 16,393
Urinary Tract 46 | 16,678
Cardiovascular System 45 | 15,192

Target Family

Non-IDG 23 | 12,091
Enzyme 14 | 4,145
Epigenetic 6 | 242
Transcription Factor 5 | 1,400

KEGG Pathway

Notch signaling pathway 48 | 48
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,3-N-acetylglucosaminyltransferase radical fringe RFNG Tdark Enzyme -0.37913 1.57 92
Numb-like protein NUMBL Tbio Non-IDG -2.50313 317.9 171
Probable E3 ubiquitin-protein ligase DTX2 DTX2 Tbio Enzyme -1.74890 58.1 123
Delta-like protein 3 DLL3 Tbio Non-IDG -1.68978 48.6 214
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
Gamma-secretase subunit PEN-2 PSENEN Tchem Enzyme -2.84761 677.3 204
C-terminal-binding protein 2 CTBP2 Tchem Non-IDG -2.63977 410.7 251
Recombining binding protein suppressor of hairless-like protein RBPJL Tbio Transcription Factor -1.54648 33.1 104
Beta-1,3-N-acetylglucosaminyltransferase manic fringe MFNG Tbio Enzyme -0.83827 6.67 114
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe LFNG Tbio Enzyme -1.50535 29.8 220