Development Level

Tchem 29 | 1,598
Tbio 22 | 11,445
Tclin 16 | 613

IMPC Phenotype

decreased body weight 4 | 161
preweaning lethality, complete... 4 | 979
abnormal bone mineralization 3 | 38
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased bone mineral density 2 | 126
decreased circulating choleste... 2 | 93
decreased circulating creatini... 2 | 39
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased total body fat amoun... 2 | 207
increased circulating choleste... 2 | 66
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal glucose homeostasis 1 | 4
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased IgG3 level 1 | 1
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mature B cell number 1 | 7
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating glucose ... 1 | 24
increased erythrocyte cell num... 1 | 39
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
male infertility 1 | 123
microphthalmia 1 | 26
prenatal lethality 1 | 28
short tibia 1 | 97
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56
thrombocytosis 1 | 27

Disease

Cancer 55 | 2,499
Carcinoma 50 | 11,493
ovarian cancer 50 | 8,520
osteosarcoma 44 | 7,950
lung cancer 36 | 4,740
glioblastoma 34 | 5,792
medulloblastoma, large-cell 34 | 6,241
psoriasis 32 | 6,694
Breast cancer 30 | 3,578
atypical teratoid / rhabdoid tumor 28 | 5,112
group 3 medulloblastoma 25 | 4,104
Breast Neoplasms 21 | 445
Mammary Neoplasms 21 | 425
Stomach Neoplasms 21 | 300
malignant mesothelioma 21 | 3,232
Kidney cancer 20 | 2,613
ependymoma 20 | 4,679
Lung Neoplasms 19 | 232
Prostatic Neoplasms 19 | 495
primitive neuroectodermal tumor 19 | 3,035
adult high grade glioma 17 | 3,801
subependymal giant cell astrocytoma 17 | 2,287
pancreatic cancer 16 | 2,398
Orbital separation excessive 15 | 244
Rheumatoid arthritis 15 | 1,191
oligodendroglioma 15 | 2,850
Astrocytoma, Pilocytic 14 | 3,081
Autosomal recessive predisposition 14 | 1,442
Hypoplastic mandible condyle 14 | 275
Mandibular hypoplasia 14 | 275
Melanoma 14 | 711
Micrognathism 14 | 275
Schizophrenia 14 | 1,160
astrocytic glioma 14 | 2,597
invasive ductal carcinoma 14 | 2,951
non-small cell lung carcinoma 14 | 317
Adenocarcinoma 13 | 122
Adenoma 13 | 167
Carcinoma, Hepatocellular 13 | 228
Carcinoma, Non-Small-Cell Lung 13 | 107
Intellectual disability 13 | 1,016
Liver carcinoma 13 | 240
Short stature 13 | 531
Squamous cell carcinoma 13 | 129
Vascular disease 13 | 319
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
juvenile dermatomyositis 13 | 1,187
lung adenocarcinoma 13 | 2,716
Blepharoptosis 12 | 231
Byzanthine arch palate 12 | 194
Carcinoma, Squamous Cell 12 | 110
Dull intelligence 12 | 645
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Neoplasm Metastasis 12 | 168
Papilloma 12 | 44
Poor school performance 12 | 645
astrocytoma 12 | 1,146
interstitial cystitis 12 | 2,312
nasopharyngeal carcinoma 12 | 1,058
tuberculosis 12 | 2,010
Acquired scoliosis 11 | 281
Adenocarcinoma of lung (disorder) 11 | 60
Cognitive delay 11 | 608
Concave bridge of nose 11 | 195
Curvature of spine 11 | 282
Depressed nasal bridge 11 | 195
Depressed nasal root/bridge 11 | 195
Downward slant of palpebral fissure 11 | 158
Epilepsy 11 | 792
Global developmental delay 11 | 608
High forehead 11 | 102
Lymphoid leukemia 11 | 160
Mammary Neoplasms, Animal 11 | 136
Mammary Neoplasms, Experimental 11 | 154
Mental and motor retardation 11 | 608
Muscle hypotonia 11 | 571
Seizures 11 | 596
Tall forehead 11 | 102
adrenocortical carcinoma 11 | 1,428
ductal carcinoma in situ 11 | 1,745
group 4 medulloblastoma 11 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
pituitary cancer 11 | 1,972
ulcerative colitis 11 | 1,819
Adenocarcinoma of lung 10 | 142
Frontal bossing 10 | 157
Immune system cancer 10 | 140
Increased head circumference 10 | 147
Increased size of cranium 10 | 147
Increased size of skull 10 | 147
Liver neoplasms 10 | 130
Multiple myeloma 10 | 1,332
Pectus excavatum 10 | 100
Strabismus 10 | 270
dermatomyositis 10 | 966
diabetes mellitus 10 | 1,728
lung carcinoma 10 | 2,843
spina bifida 10 | 1,074

Tissue

Blood and immune system 66 | 16,909
Digestive Tract 66 | 17,369
Endocrine System 66 | 18,159
Female tissues 66 | 17,400
Liver and Pancreas 66 | 16,750
Male tissues 66 | 17,142
Nervous System 66 | 16,725
Skin and soft tissues 66 | 17,230
Respiratory system 65 | 16,393
Urinary Tract 65 | 16,678
Cardiovascular System 63 | 15,192

Target Family

Kinase 25 | 634
Non-IDG 18 | 12,091
Enzyme 12 | 4,145
Transcription Factor 8 | 1,400
Nuclear Receptor 4 | 48

KEGG Pathway

Non-small cell lung cancer 67 | 67
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras association domain-containing protein 5 RASSF5 Tbio Non-IDG -1.81149 71.3 155
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
Echinoderm microtubule-associated protein-like 4 EML4 Tbio Non-IDG -2.42152 197.5 83
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.41628 245.1 733
ALK tyrosine kinase receptor ALK Tclin Kinase -3.44312 2942.9 976