Development Level

Tclin 30 | 613
Tbio 4 | 11,445
Tchem 4 | 1,598
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 4 | 99

IMPC Phenotype

abnormal epididymis morphology 2 | 42
enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased neutrophil cell numb... 1 | 42
decreased vertical activity 1 | 208
hyperactivity 1 | 148
increased circulating alanine ... 1 | 13
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased startle reflex 1 | 112
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 36 | 11,493
Epilepsy 29 | 792
General anesthesia 27 | 53
Schizophrenia 27 | 1,160
atypical teratoid / rhabdoid tumor 26 | 5,112
glioblastoma 26 | 5,792
medulloblastoma, large-cell 26 | 6,241
ependymoma 25 | 4,679
adult high grade glioma 24 | 3,801
Astrocytoma, Pilocytic 22 | 3,081
Bipolar Disorder 22 | 666
oligodendroglioma 21 | 2,850
primitive neuroectodermal tumor 21 | 3,035
Kidney cancer 20 | 2,613
Tonic-clonic epilepsy 20 | 47
Local anesthesia 19 | 40
Anxiety 17 | 136
astrocytic glioma 17 | 2,597
psoriasis 17 | 6,694
Alcoholic Intoxication, Chronic 16 | 289
Autistic Disorder 16 | 364
Insomnia 16 | 20
group 3 medulloblastoma 15 | 4,104
lung carcinoma 14 | 2,843
Parkinson's disease 13 | 392
Sedation as Adjunct to Anesthesia 13 | 15
Alcohol dependence 11 | 107
Alcoholism 11 | 45
Pick disease 11 | 1,894
subependymal giant cell astrocytoma 11 | 2,287
Intellectual disability 10 | 1,016
Lennox-Gastaut syndrome 10 | 34
ovarian cancer 10 | 8,520
Depressive disorder 9 | 409
Mental Depression 9 | 333
Simple partial seizure 9 | 26
Status Epilepticus 9 | 98
Tetanus 9 | 68
osteosarcoma 9 | 7,950
pituitary cancer 9 | 1,972
Alcohol withdrawal delirium 8 | 11
Alcohol withdrawal syndrome 8 | 20
Benzodiazepine Induced Sedation 8 | 8
Benzodiazepine Maintained Anesthesia 8 | 8
Benzodiazepine Toxicity 8 | 8
Induce Anterograde Amnesia 8 | 9
Preoperative Anxiety 8 | 9
Sedation 8 | 11
Sedation in Intubated Patients 8 | 8
Spasticity 8 | 26
Toxic encephalopathy 8 | 141
Alzheimer's disease 7 | 658
Anxiety associated with Menopause 7 | 7
Arteriosclerotic Parkinsonism 7 | 8
Breast cancer 7 | 3,578
Conscious sedation 7 | 10
Epilepsy characterized by intractable complex partial seizures 7 | 28
Extrapyramidal disease 7 | 8
Feeling agitated 7 | 7
Generalized anxiety disorder 7 | 29
Influenza A Prevention 7 | 7
Influenza due to Influenza A virus 7 | 7
Irritable bowel syndrome 7 | 60
Migraine Prevention 7 | 23
Mixed anxiety and depressive disorder 7 | 12
Panic disorder 7 | 61
Parkinsonism 7 | 18
Partial Epilepsy Treatment Adjunct 7 | 16
Peptic Ulcer 7 | 27
Postencephalitic parkinsonism 7 | 12
Pre-Op Apprehension 7 | 10
Schizoaffective Disorder 7 | 55
Seizures 7 | 596
Severe Insomnia 7 | 7
Severe anxiety (panic) 7 | 7
lung cancer 7 | 4,740
Dull intelligence 6 | 645
Initial insomnia 6 | 8
Low intelligence 6 | 645
Major Depressive Disorder 6 | 301
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Mood Disorders 6 | 184
Pain with Tension and Anxiety 6 | 6
Poor school performance 6 | 645
Cocaine-Related Disorders 5 | 92
Disorders of initiating and maintaining sleep 5 | 8
Liver cancer 5 | 604
Nicotine dependence 5 | 54
Substance Withdrawal Syndrome 5 | 55
group 4 medulloblastoma 5 | 1,855
non primary Sjogren syndrome sicca 5 | 891
Abnormal behavior 4 | 52
Cognitive delay 4 | 608
Electroencephalogram abnormal 4 | 101
Melanoma 4 | 711
Mental and motor retardation 4 | 608
Skin cancer 4 | 469
gastric carcinoma 4 | 807
lung adenocarcinoma 4 | 2,716

Tissue

Endocrine System 38 | 18,159
Nervous System 37 | 16,725
Female tissues 33 | 17,400
Digestive Tract 32 | 17,369
Blood and immune system 31 | 16,909
Skin and soft tissues 31 | 17,230
Male tissues 28 | 17,142
Urinary Tract 26 | 16,678
Liver and Pancreas 25 | 16,750
Respiratory system 21 | 16,393
Cardiovascular System 18 | 15,192

Target Family

Ion Channel 35 | 344
Transporter 4 | 473

KEGG Pathway

Nicotine addiction 39 | 39
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuronal acetylcholine receptor subunit beta-2 CHRNB2 Tclin Ion Channel -1.62448 37.6 174
Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 Tbio Ion Channel -1.74365 53.9 92
Gamma-aminobutyric acid receptor subunit beta-3 GABRB3 Tclin Ion Channel -2.13205 136.0 202
Gamma-aminobutyric acid receptor subunit alpha-1 GABRA1 Tclin Ion Channel -1.79984 58.4 301
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.28622 17.7 291
Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 Tclin Ion Channel -0.98683 8.48 87
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.24422 170.7 75
Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 Tdark Ion Channel -1.69677 48.3 41
Gamma-aminobutyric acid receptor subunit rho-1 GABRR1 Tchem Ion Channel -1.72375 51.4 148
Gamma-aminobutyric acid receptor subunit theta GABRQ Tclin Ion Channel -0.83091 6.58 66