Development Level

Tbio 85 | 11,445
Tchem 43 | 1,598
Tclin 13 | 613
Tdark 13 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to o... 4 | 239
increased neutrophil cell numb... 4 | 46
abnormal behavior 3 | 298
abnormal embryo size 3 | 220
decreased lymphocyte cell numb... 3 | 83
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
small superior vagus ganglion 3 | 74
abnormal coat- hair morphology 2 | 19
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
decreased circulating glucose ... 2 | 126
decreased mean corpuscular hem... 2 | 50
decreased total retina thickne... 2 | 17
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
hypoactivity 2 | 132
increased eosinophil cell numb... 2 | 11
increased erythrocyte cell num... 2 | 39
increased grip strength 2 | 41
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
increased monocyte cell number 2 | 63
prenatal lethality prior to he... 2 | 87
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal gait 1 | 69
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retinal inner nuclear... 1 | 8
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
abnormal vitreous body morphol... 1 | 10
absent testes 1 | 6
absent vibrissae 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased mean corpuscular vol... 1 | 79
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
enlarged uterus 1 | 11
hydrometra 1 | 53
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased basophil cell number 1 | 7
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased large unstained cell... 1 | 5
increased spleen weight 1 | 10
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499
protruding tongue 1 | 3
short tibia 1 | 97

Disease

Carcinoma 84 | 11,493
ovarian cancer 80 | 8,520
osteosarcoma 68 | 7,950
psoriasis 66 | 6,694
Cancer 64 | 2,499
lung cancer 62 | 4,740
medulloblastoma, large-cell 53 | 6,241
glioblastoma 51 | 5,792
malignant mesothelioma 48 | 3,232
atypical teratoid / rhabdoid tumor 43 | 5,112
Breast cancer 41 | 3,578
adult high grade glioma 33 | 3,801
Astrocytoma, Pilocytic 32 | 3,081
lung adenocarcinoma 32 | 2,716
tuberculosis 32 | 2,010
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
lung carcinoma 30 | 2,843
subependymal giant cell astrocytoma 30 | 2,287
ependymoma 29 | 4,679
Multiple myeloma 28 | 1,332
group 3 medulloblastoma 28 | 4,104
cutaneous lupus erythematosus 26 | 1,057
invasive ductal carcinoma 25 | 2,951
non-small cell lung cancer 25 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 24 | 1,962
pancreatic cancer 23 | 2,398
Multiple Sclerosis 22 | 540
diabetes mellitus 22 | 1,728
group 4 medulloblastoma 22 | 1,855
ulcerative colitis 22 | 1,819
Rheumatoid arthritis 21 | 1,191
interstitial cystitis 20 | 2,312
pituitary cancer 20 | 1,972
Arthritis 19 | 290
Hypersensitivity reaction type II disease 19 | 253
Schizophrenia 19 | 1,160
dermatomyositis 19 | 966
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
primitive neuroectodermal tumor 19 | 3,035
Kidney cancer 18 | 2,613
juvenile dermatomyositis 18 | 1,187
Vascular disease 17 | 319
cystic fibrosis 17 | 1,696
Asthma 16 | 385
Autosomal recessive predisposition 16 | 1,442
Bipolar Disorder 16 | 666
Inflammatory bowel disease 16 | 151
ductal carcinoma in situ 16 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
Breast Neoplasms 15 | 445
Fever 15 | 138
Liver Cirrhosis, Experimental 15 | 769
Mammary Neoplasms 15 | 425
oligodendroglioma 15 | 2,850
primary Sjogren syndrome 15 | 735
Anemia 14 | 365
Depressive disorder 14 | 409
Dermatitis 14 | 157
Neurodegenerative disease 14 | 414
acute quadriplegic myopathy 14 | 1,158
astrocytic glioma 14 | 2,597
breast carcinoma 14 | 1,638
colon cancer 14 | 1,478
hepatocellular carcinoma 14 | 547
pancreatic carcinoma 14 | 562
Lung disease 13 | 142
Alzheimer's disease 12 | 658
Inflammation 12 | 120
Influenza 12 | 142
Kidney disease 12 | 430
Pneumonia 12 | 174
Waldenstrons macroglobulinemia 12 | 765
non-small cell lung carcinoma 12 | 317
Carcinoma, Hepatocellular 11 | 228
Crohn's disease 11 | 321
Liver carcinoma 11 | 240
Melanoma 11 | 711
Obesity 11 | 678
Prostatic Neoplasms 11 | 495
Reperfusion Injury 11 | 86
adrenocortical carcinoma 11 | 1,428
esophageal adenocarcinoma 11 | 737
primary pancreatic ductal adenocarcinoma 11 | 1,109
Atherosclerosis 10 | 291
Atopic dermatitis 10 | 952
Diarrhea 10 | 253
Fatigue 10 | 182
Liver disease 10 | 237
Myocardial Ischemia 10 | 169
Neoplasm Metastasis 10 | 168
Pick disease 10 | 1,894
Amyotrophic lateral sclerosis 9 | 451
Colonic Neoplasms 9 | 142
Endometriosis 9 | 540
Hepatitis B 9 | 108
Lung Neoplasms 9 | 232
Stomach Neoplasms 9 | 300
Vasculitis 9 | 80
active Crohn's disease 9 | 922
spina bifida 9 | 1,074

Tissue

Blood and immune system 143 | 16,909
Endocrine System 141 | 18,159
Digestive Tract 140 | 17,369
Female tissues 140 | 17,400
Skin and soft tissues 140 | 17,230
Male tissues 139 | 17,142
Nervous System 138 | 16,725
Urinary Tract 138 | 16,678
Liver and Pancreas 137 | 16,750
Respiratory system 137 | 16,393
Cardiovascular System 135 | 15,192

Target Family

Non-IDG 97 | 12,091
Enzyme 27 | 4,145
Kinase 15 | 634
Transcription Factor 9 | 1,400
Transporter 4 | 473
Ion Channel 2 | 344

KEGG Pathway

Necroptosis 154 | 154
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin carboxyl-terminal hydrolase 21 USP21 Tbio Enzyme -1.64460 44.9 288
Histone H2A.J H2AFJ Tdark Non-IDG -0.00172 0.83 99
Poly [ADP-ribose] polymerase 4 PARP4 Tchem Enzyme -1.45503 26.0 123
Histone H2A type 1-A HIST1H2AA Tbio Non-IDG -0.84480 8.19 69
Cytosolic phospholipase A2 delta PLA2G4D Tbio Enzyme -0.54284 3.41 45
TIR domain-containing adapter molecule 2 TICAM2 Tbio Non-IDG -1.18212 14.6 258
Transient receptor potential cation channel subfamily M member 7 TRPM7 Tchem Ion Channel -2.53154 365.5 317
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344
Charged multivesicular body protein 1a CHMP1A Tbio Non-IDG -1.15571 14.9 161