Development Level

Tbio 136 | 10,625
Tchem 40 | 1,890
Tclin 12 | 602
Tdark 11 | 7,003

IMPC Phenotype

decreased body weight 3 | 174
decreased circulating creatini... 2 | 31
preweaning lethality, complete... 2 | 633
preweaning lethality, incomple... 2 | 260
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal gait 1 | 51
abnormal lens morphology 1 | 73
cataract 1 | 26
decreased B cell number 1 | 30
decreased CD5-positive Ly6C-po... 1 | 4
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased Ly6C low monocyte nu... 1 | 23
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating bilirubi... 1 | 14
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating magnesiu... 1 | 11
decreased circulating triglyce... 1 | 83
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased mature B cell number 1 | 25
decreased monocyte cell number 1 | 28
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
increased B cell number 1 | 23
increased IgG1 level 1 | 1
increased NK cell number 1 | 19
increased T cell number 1 | 15
increased blood urea nitrogen ... 1 | 44
increased hemoglobin content 1 | 45
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased startle reflex 1 | 38
male infertility 1 | 62
short tibia 1 | 82

Disease

Cancer 142 | 2,346
psoriasis 104 | 6,685
Ankylosing spondylitis 75 | 138
Hypersensitivity reaction type II disease 72 | 235
diabetes mellitus 72 | 1,663
Arthritis 68 | 248
osteosarcoma 64 | 7,933
Acquired immunodeficiency syndrome 63 | 164
Uveitis 60 | 103
ovarian cancer 59 | 8,491
Behcet's disease 58 | 74
Human immunodeficiency virus infectious disease 58 | 129
Juvenile rheumatoid arthritis 57 | 105
Rheumatoid Arthritis 54 | 1,170
Stevens-Johnson syndrome 53 | 91
lung cancer 53 | 4,473
Psoriatic arthritis 51 | 85
dermatomyositis 50 | 966
glioblastoma 43 | 5,572
Dermatitis 40 | 141
Multiple Sclerosis 39 | 498
medulloblastoma, large-cell 39 | 6,234
Synovitis 37 | 72
Takayasu's arteritis 37 | 54
lung carcinoma 37 | 2,844
Behcet's syndrome 36 | 50
pilocytic astrocytoma 36 | 3,086
Congenital adrenal hyperplasia 35 | 74
Nephritis 35 | 63
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
interstitial cystitis 35 | 2,299
subependymal giant cell astrocytoma 33 | 2,287
Anemia 31 | 252
Hepatitis B 31 | 103
ulcerative colitis 31 | 2,087
Liver disease 30 | 219
Kidney disease 29 | 397
cutaneous lupus erythematosus 29 | 1,056
Primary immunodeficiency disease 27 | 52
non-small cell lung cancer 26 | 2,798
atypical teratoid / rhabdoid tumor 25 | 4,369
invasive ductal carcinoma 25 | 2,950
tuberculosis 25 | 1,563
Skin disease 24 | 65
Leprosy 23 | 77
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,289
malignant mesothelioma 23 | 3,163
pancreatic cancer 23 | 2,300
Carcinoma 22 | 2,147
Hemochromatosis 22 | 55
astrocytoma 22 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,988
Birdshot chorioretinopathy 21 | 23
juvenile dermatomyositis 21 | 1,189
pediatric high grade glioma 21 | 2,712
Breast cancer 20 | 3,098
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,956
primary Sjogren syndrome 20 | 788
Multiple myeloma 19 | 1,327
oligodendroglioma 19 | 2,849
ependymoma 18 | 2,514
lung adenocarcinoma 18 | 2,714
primitive neuroectodermal tumor 17 | 3,031
Human immunodeficiency virus type 1, susceptibility to 16 | 26
Melanoma 16 | 261
medulloblastoma 16 | 1,524
group 4 medulloblastoma 15 | 1,875
pre-eclampsia 15 | 67
Psoriasis susceptibility 1 14 | 14
adult high grade glioma 14 | 2,148
Hepatitis C 12 | 90
Mammary Neoplasms 12 | 410
Pick disease 12 | 1,893
cystic fibrosis 12 | 1,670
gastric carcinoma 12 | 832
posterior fossa group A ependymoma 12 | 1,511
Asthma 11 | 349
Influenza 11 | 142
Stomach Neoplasms 11 | 282
astrocytic glioma 11 | 2,241
Hepatitis 10 | 61
Lung Neoplasms 10 | 171
Noonan Syndrome 10 | 33
breast carcinoma 10 | 1,614
colon cancer 10 | 1,475
nasopharyngeal carcinoma 10 | 1,056
pituitary cancer 10 | 1,972
primary pancreatic ductal adenocarcinoma 10 | 1,271
Colorectal Neoplasms 9 | 217
Down syndrome 9 | 548
Lung disease 9 | 136
Prostatic Neoplasms 9 | 471
Renal Cell Carcinoma 9 | 199
Waldenstrons macroglobulinemia 9 | 764
esophageal adenocarcinoma 9 | 737
periodontitis 9 | 269
sarcoidosis 9 | 368
tuberculosis and treatment for 6 months 9 | 686

Tissue

Blood and immune system 129 | 17,994
Nervous System 129 | 18,560
Female tissues 128 | 18,646
Digestive Tract 127 | 18,472
Urinary Tract 126 | 18,443
Endocrine System 123 | 18,511
Cardiovascular System 120 | 17,957
Liver and Pancreas 120 | 18,135
Skin and soft tissues 120 | 18,114
Respiratory system 119 | 17,483
Male tissues 114 | 17,968

Target Family

Non-IDG 157 | 11,969
Kinase 21 | 634
Enzyme 19 | 4,146
Transcription Factor 2 | 1,400

KEGG Pathway

Natural killer cell mediated c... 199 | 199
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interferon gamma receptor 1 IFNGR1 Tchem Non-IDG -2.19638 160.9 450
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.87358 1568.8 0
Serine/threonine-protein kinase B-raf BRAF Tclin Kinase -2.28702 199.1 1276
GTPase KRas KRAS Tbio Enzyme -3.77389 5694.2 421
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.39396 233.2 634
HLA class I histocompatibility antigen, A-80 alpha chain HLA-A Tbio Non-IDG -2.40709 4042.7 0
Proto-oncogene vav VAV1 Tchem Non-IDG -2.64007 465.9 479
Guanine nucleotide exchange factor VAV2 VAV2 Tbio Non-IDG -1.78476 58.3 173
GTPase HRas HRAS Tchem Enzyme -3.99319 9497.9 312
GTPase NRas NRAS Tchem Enzyme -2.98048 880.4 265