Development Level

Tbio 147 | 11,651
Tchem 27 | 1,388
Tclin 13 | 612
Tdark 10 | 6,593

IMPC Phenotype

preweaning lethality, complete... 7 | 979
decreased body weight 3 | 161
abnormal bone structure 2 | 187
abnormal lens morphology 2 | 81
cataract 2 | 92
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating creatini... 2 | 39
enlarged heart 2 | 210
increased erythrocyte cell num... 2 | 39
increased total body fat amoun... 2 | 134
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal digit morphology 1 | 10
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
decreased IgG3 level 1 | 1
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating magnesiu... 1 | 13
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
prenatal lethality 1 | 28
thin ventricular wall 1 | 24

Disease

Cancer 145 | 2,499
Carcinoma 104 | 11,493
psoriasis 104 | 6,694
Ankylosing spondylitis 74 | 140
Hypersensitivity reaction type II disease 73 | 253
Behcet's disease 72 | 89
diabetes mellitus 72 | 1,728
Arthritis 69 | 290
Acquired immunodeficiency syndrome 63 | 197
osteosarcoma 62 | 7,950
Human immunodeficiency virus infectious disease 61 | 138
Uveitis 60 | 103
Juvenile rheumatoid arthritis 59 | 111
ovarian cancer 58 | 8,520
Herpes zoster 57 | 68
lung cancer 55 | 4,740
Rheumatoid arthritis 54 | 1,191
Stevens-Johnson syndrome 53 | 92
Psoriatic arthritis 51 | 86
tuberculosis 51 | 2,010
dermatomyositis 50 | 966
glioblastoma 46 | 5,792
Dermatitis 40 | 157
Synovitis 40 | 78
medulloblastoma, large-cell 39 | 6,241
Multiple Sclerosis 38 | 540
Takayasu's arteritis 37 | 53
Behcet's syndrome 36 | 50
Nephritis 36 | 51
Congenital adrenal hyperplasia 35 | 73
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
lung carcinoma 35 | 2,843
Anemia 34 | 365
interstitial cystitis 33 | 2,312
Astrocytoma, Pilocytic 31 | 3,081
Hepatitis B 31 | 108
subependymal giant cell astrocytoma 31 | 2,287
Kidney disease 29 | 430
Liver disease 29 | 237
atypical teratoid / rhabdoid tumor 29 | 5,112
cutaneous lupus erythematosus 29 | 1,057
Primary immunodeficiency disease 26 | 54
Schizophrenia 26 | 1,160
ependymoma 26 | 4,679
malignant mesothelioma 26 | 3,232
ulcerative colitis 26 | 1,819
adult high grade glioma 25 | 3,801
Skin disease 24 | 66
non-small cell lung cancer 24 | 2,890
pancreatic cancer 24 | 2,398
Breast cancer 23 | 3,578
Leprosy 23 | 73
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
invasive ductal carcinoma 23 | 2,951
Hemochromatosis 22 | 54
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
Birdshot chorioretinopathy 21 | 23
group 4 medulloblastoma 21 | 1,855
juvenile dermatomyositis 21 | 1,187
Kidney cancer 20 | 2,613
Multiple myeloma 20 | 1,332
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
Melanoma 19 | 711
oligodendroglioma 19 | 2,850
lung adenocarcinoma 18 | 2,716
primary Sjogren syndrome 18 | 735
astrocytoma 17 | 1,146
primitive neuroectodermal tumor 17 | 3,035
Human immunodeficiency virus type 1, susceptibility to 16 | 26
Liver Cirrhosis, Experimental 16 | 769
astrocytic glioma 16 | 2,597
group 3 medulloblastoma 16 | 4,104
Pre-Eclampsia 15 | 68
Autosomal recessive predisposition 14 | 1,442
Psoriasis susceptibility 1 14 | 14
Hepatitis C 13 | 94
Lymphoproliferative syndrome 13 | 58
cystic fibrosis 13 | 1,696
Breast Neoplasms 12 | 445
Hepatomegaly 12 | 285
Mammary Neoplasms 12 | 425
Muscle hypotonia 12 | 571
Orbital separation excessive 12 | 244
Pick disease 12 | 1,894
Short stature 12 | 531
Stomach Neoplasms 12 | 300
breast carcinoma 12 | 1,638
gastric carcinoma 12 | 807
Blepharoptosis 11 | 231
Byzanthine arch palate 11 | 194
High forehead 11 | 102
Hypoplastic mandible condyle 11 | 275
Influenza 11 | 142
Lung Neoplasms 11 | 232
Mandibular hypoplasia 11 | 275
Micrognathism 11 | 275
Seizures 11 | 596
Tall forehead 11 | 102

Tissue

Blood and immune system 106 | 16,909
Digestive Tract 101 | 17,369
Endocrine System 101 | 18,159
Liver and Pancreas 100 | 16,750
Male tissues 100 | 17,142
Female tissues 99 | 17,400
Skin and soft tissues 99 | 17,230
Urinary Tract 99 | 16,678
Respiratory system 98 | 16,393
Nervous System 97 | 16,725
Cardiovascular System 93 | 15,192

Target Family

Non-IDG 157 | 12,091
Kinase 20 | 634
Enzyme 18 | 4,145
Transcription Factor 2 | 1,400

KEGG Pathway

Natural killer cell mediated c... 197 | 197
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
Tyrosine-protein kinase ZAP-70 ZAP70 Tchem Kinase -2.91589 798.2 1515
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0