Development Level

Tbio 93 | 10,625
Tchem 58 | 1,890
Tclin 11 | 602
Tdark 6 | 7,003

Collection

Eligible Ion Channel Proteins 1 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 11 | 633
embryonic lethality prior to t... 5 | 187
abnormal embryo size 3 | 112
decreased bone mineral content 3 | 157
abnormal forebrain development 2 | 18
abnormal hindbrain development 2 | 24
abnormal lens morphology 2 | 73
abnormal midbrain development 2 | 22
abnormal neural tube closure 2 | 37
decreased circulating amylase ... 2 | 24
decreased circulating insulin ... 2 | 75
decreased lean body mass 2 | 195
decreased mean corpuscular vol... 2 | 50
embryonic lethality prior to o... 2 | 148
increased grip strength 2 | 83
male infertility 2 | 62
persistence of hyaloid vascula... 2 | 22
prenatal lethality prior to he... 2 | 64
abnormal behavior 1 | 226
abnormal brain morphology 1 | 6
abnormal coat/ hair morphology 1 | 18
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal heart morphology 1 | 51
abnormal neural tube morpholog... 1 | 8
abnormal retina morphology 1 | 100
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 23
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal vocalization 1 | 21
absent vibrissae 1 | 14
cataract 1 | 26
decreased CD5-positive Ly6C-po... 1 | 4
decreased KLRG1+ CD8 alpha bet... 1 | 8
decreased Ly6C low monocyte nu... 1 | 23
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased cardiac stroke volum... 1 | 3
decreased caudal vertebrae num... 1 | 49
decreased circulating alkaline... 1 | 41
decreased circulating bilirubi... 1 | 14
decreased circulating glycerol... 1 | 19
decreased circulating serum al... 1 | 79
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased monocyte cell number 1 | 28
decreased neutrophil cell numb... 1 | 37
decreased thermal nociceptive ... 1 | 4
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
female infertility 1 | 34
hydroencephaly 1 | 6
hypoactivity 1 | 89
impaired righting response 1 | 19
increased B cell number 1 | 23
increased NK cell number 1 | 19
increased body weight 1 | 42
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating free fat... 1 | 17
increased circulating glucose ... 1 | 16
increased circulating phosphat... 1 | 24
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased leukocyte cell numbe... 1 | 37
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased spleen weight 1 | 3
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 57
pale yolk sac 1 | 12
polydactyly 1 | 22
preweaning lethality, incomple... 1 | 260
small epididymis 1 | 3
small superior vagus ganglion 1 | 20
stereotypic behavior 1 | 3
thrombocytopenia 1 | 46
trunk curl 1 | 15

Disease

ovarian cancer 89 | 8,484
psoriasis 85 | 6,685
osteosarcoma 81 | 7,933
Cancer 66 | 2,346
glioblastoma 64 | 5,572
lung cancer 64 | 4,466
medulloblastoma, large-cell 52 | 6,234
lung carcinoma 51 | 2,844
malignant mesothelioma 44 | 3,162
pancreatic cancer 43 | 2,300
ulcerative colitis 42 | 2,087
pilocytic astrocytoma 41 | 3,086
tuberculosis 41 | 1,557
subependymal giant cell astrocytoma 39 | 2,287
cystic fibrosis 38 | 1,665
atypical teratoid / rhabdoid tumor 37 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,289
lung adenocarcinoma 34 | 2,713
invasive ductal carcinoma 33 | 2,950
non-small cell lung cancer 33 | 2,798
Breast cancer 31 | 3,094
juvenile dermatomyositis 31 | 1,189
interstitial cystitis 30 | 2,299
cutaneous lupus erythematosus 29 | 1,056
diabetes mellitus 27 | 1,663
group 4 medulloblastoma 27 | 1,875
Arthritis 26 | 248
Multiple Sclerosis 25 | 498
Rheumatoid Arthritis 25 | 1,160
adult high grade glioma 25 | 2,148
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,988
pituitary cancer 25 | 1,972
posterior fossa group A ependymoma 23 | 1,511
Multiple myeloma 22 | 1,327
pediatric high grade glioma 22 | 2,712
Carcinoma 21 | 2,147
Influenza 21 | 142
Vascular disease 21 | 281
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,956
Kidney disease 20 | 396
Pick disease 20 | 1,893
primary Sjogren syndrome 20 | 789
ependymoma 19 | 2,514
oligodendroglioma 19 | 2,849
Asthma 18 | 349
Obesity 18 | 616
active Crohn's disease 18 | 918
pancreatic carcinoma 18 | 567
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,795
primitive neuroectodermal tumor 18 | 3,031
Inflammatory bowel disease 17 | 142
Lung disease 17 | 132
Reperfusion Injury 17 | 84
acute quadriplegic myopathy 17 | 1,157
astrocytoma 17 | 1,493
hepatocellular carcinoma 17 | 532
Neurodegenerative disease 16 | 383
breast carcinoma 16 | 1,614
colon cancer 16 | 1,475
dermatomyositis 16 | 933
sarcoidosis 16 | 358
Alzheimer's disease 15 | 644
Atherosclerosis 15 | 275
Dermatitis 15 | 107
Hypersensitivity reaction type II disease 15 | 235
acute myeloid leukemia 15 | 780
esophageal adenocarcinoma 15 | 737
gastric carcinoma 15 | 832
primary pancreatic ductal adenocarcinoma 15 | 1,271
Heart disease 14 | 279
Mammary Neoplasms 14 | 410
Waldenstrons macroglobulinemia 14 | 765
astrocytic glioma 14 | 2,241
gastric cancer 14 | 430
Crohn's disease 13 | 304
Stomach Neoplasms 13 | 282
Atopic dermatitis 12 | 944
Brain Ischemia 12 | 87
Hypertension 12 | 287
Lung Neoplasms 12 | 171
Prostatic Neoplasms 12 | 471
adrenocortical carcinoma 12 | 1,427
group 3 medulloblastoma 12 | 2,254
posterior fossa group B ependymoma 12 | 1,530
spina bifida 12 | 1,064
Coronary artery disease 11 | 240
IGA Glomerulonephritis 11 | 454
Inflammation 11 | 109
Peritonitis 11 | 37
Pneumonia 11 | 133
Toxic encephalopathy 11 | 131
head and neck cancer 11 | 270
medulloblastoma 11 | 1,524
systemic lupus erythematosus 11 | 156
Amyotrophic Lateral Sclerosis 10 | 431
Bipolar Disorder 10 | 266
Cerebrovascular disease 10 | 231
Hepatitis C 10 | 90
Meningitis 10 | 46
mucosa-associated lymphoid tissue lymphoma 10 | 480

Tissue

Nervous System 166 | 18,561
Digestive Tract 164 | 18,473
Female tissues 164 | 18,647
Urinary Tract 164 | 18,444
Blood and immune system 160 | 17,995
Skin and soft tissues 160 | 18,115
Endocrine System 159 | 18,512
Cardiovascular System 156 | 17,958
Liver and Pancreas 156 | 18,136
Male tissues 153 | 17,969
Respiratory system 153 | 17,484

Target Family

Non-IDG 92 | 11,971
Enzyme 30 | 4,146
Kinase 25 | 634
Ion Channel 10 | 341
Transcription Factor 8 | 1,400
GPCR 2 | 406
Epigenetic 1 | 242

KEGG Pathway

NOD-like receptor signaling pa... 168 | 168
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Interferon regulatory factor 9 IRF9 Tbio Transcription Factor -1.79340 61.7 168
TNF receptor-associated factor 2 TRAF2 Tbio Non-IDG -1.85843 68.9 516
Cytochrome b-245 light chain CYBA Tbio Non-IDG -2.56294 358.8 154
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TAB2 Tbio Enzyme -1.83055 69.0 145
Calcium uniporter protein, mitochondrial MCU Tbio Ion Channel -2.59256 408.9 18
Mitofusin-1 MFN1 Tbio Non-IDG -1.99234 91.2 0
Interferon alpha/beta receptor 2 IFNAR2 Tclin Non-IDG -1.87993 74.0 225
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34160 1960.9 1181
Cathelicidin antimicrobial peptide CAMP Tbio Non-IDG -3.26418 1961.9 0