Development Level

Tclin 37 | 602
Tbio 26 | 10,625
Tchem 25 | 1,890
Tdark 6 | 7,003

Collection

Eligible Ion Channel Proteins 8 | 117
Eligible Kinase Proteins 2 | 134

IMPC Term

abnormal bone structure 5 | 131
abnormal behavior 4 | 226
abnormal bone mineralization 4 | 55
increased heart weight 4 | 37
hyperactivity 3 | 108
preweaning lethality, incomple... 3 | 260
decreased fasted circulating g... 2 | 49
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
increased blood urea nitrogen ... 2 | 44
increased bone mineral content 2 | 92
increased circulating alkaline... 2 | 119
increased total body fat amoun... 2 | 57
thrombocytopenia 2 | 46
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
cardiovascular system phenotyp... 1 | 35
decreased bone mineral content 1 | 157
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased grip strength 1 | 123
decreased prepulse inhibition 1 | 52
decreased respiratory quotient 1 | 12
decreased startle reflex 1 | 48
enlarged epididymis 1 | 27
enlarged heart 1 | 111
impaired righting response 1 | 19
increased circulating HDL chol... 1 | 63
increased circulating alanine ... 1 | 11
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
limb grasping 1 | 35
preweaning lethality, complete... 1 | 633
small kidney 1 | 10
small superior vagus ganglion 1 | 20
small testis 1 | 37
straub tail 1 | 26

Disease

medulloblastoma, large-cell 63 | 6,234
glioblastoma 51 | 5,572
atypical teratoid / rhabdoid tumor 48 | 4,369
pilocytic astrocytoma 44 | 3,086
primitive neuroectodermal tumor 44 | 3,031
osteosarcoma 42 | 7,933
ovarian cancer 41 | 8,484
oligodendroglioma 38 | 2,849
psoriasis 34 | 6,685
lung carcinoma 32 | 2,844
Carcinoma 31 | 2,147
astrocytic glioma 29 | 2,241
ependymoma 29 | 2,514
pediatric high grade glioma 29 | 2,712
invasive ductal carcinoma 28 | 2,950
subependymal giant cell astrocytoma 27 | 2,287
pituitary cancer 23 | 1,972
Epilepsy 22 | 346
Pick disease 22 | 1,893
Breast cancer 20 | 3,094
astrocytoma 20 | 1,493
adult high grade glioma 19 | 2,148
lung cancer 19 | 4,466
interstitial cystitis 18 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
malignant mesothelioma 18 | 3,162
medulloblastoma 18 | 1,524
General anesthesia 17 | 53
non-small cell lung cancer 17 | 2,798
posterior fossa group A ependymoma 17 | 1,511
Anxiety 16 | 24
Insomnia 16 | 20
Tonic-clonic epilepsy 16 | 47
group 3 medulloblastoma 16 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
ulcerative colitis 16 | 2,087
Atrial Fibrillation 15 | 110
Autistic Disorder 15 | 320
breast carcinoma 15 | 1,614
group 4 medulloblastoma 15 | 1,875
Myocardial Perfusion Imaging Adjunct 14 | 25
Sedation as Adjunct to Anesthesia 14 | 15
ductal carcinoma in situ 14 | 1,745
lung adenocarcinoma 14 | 2,713
Alcohol dependence 13 | 107
Chronic heart failure 13 | 46
Platelet Aggregation Inhibition 13 | 22
Prevention of Cerebral Thrombosis 13 | 29
pancreatic cancer 13 | 2,300
Dysuria 11 | 24
Urinary Tract Irritation 11 | 24
adrenocortical carcinoma 10 | 1,427
colon cancer 10 | 1,475
sonic hedgehog group medulloblastoma 10 | 1,482
Local anesthesia 9 | 40
Rheumatoid Arthritis 9 | 1,160
Schizophrenia 9 | 501
Spasticity 9 | 26
tuberculosis 9 | 1,557
Alcohol withdrawal delirium 8 | 9
Alcohol withdrawal syndrome 8 | 9
Benzodiazepine Induced Sedation 8 | 8
Benzodiazepine Maintained Anesthesia 8 | 8
Benzodiazepine Toxicity 8 | 8
Bipolar Disorder 8 | 266
Carney complex 8 | 23
Increased Urinary Frequency 8 | 11
Induce Anterograde Amnesia 8 | 9
Intellectual disability 8 | 573
Irritable bowel syndrome 8 | 59
Nocturia 8 | 8
Obesity 8 | 616
Panic disorder 8 | 55
Preoperative Anxiety 8 | 9
Sedation 8 | 11
Sedation in Intubated Patients 8 | 8
Status Epilepticus 8 | 85
Suprapubic pain 8 | 8
Tetanus 8 | 66
Urgent desire to urinate 8 | 11
Urinary incontinence 8 | 13
active Crohn's disease 8 | 918
atypical teratoid/rhabdoid tumor 8 | 1,095
cystic fibrosis 8 | 1,665
posterior fossa group B ependymoma 8 | 1,530
Acrodysostosis 7 | 9
Anxiety associated with Menopause 7 | 7
Conscious sedation 7 | 10
Cushing's syndrome 7 | 47
Feeling agitated 7 | 7
Generalized anxiety disorder 7 | 29
Mixed anxiety and depressive disorder 7 | 10
Partial Epilepsy Treatment Adjunct 7 | 16
Peptic ulcer 7 | 22
Pre-Op Apprehension 7 | 10
Severe Insomnia 7 | 7
Severe anxiety (panic) 7 | 7
primary Sjogren syndrome 7 | 789
gastric carcinoma 6 | 832

Tissue

Female tissues 93 | 18,647
Digestive Tract 92 | 18,473
Endocrine System 92 | 18,512
Nervous System 92 | 18,561
Urinary Tract 92 | 18,444
Blood and immune system 91 | 17,995
Liver and Pancreas 91 | 18,136
Male tissues 91 | 17,969
Cardiovascular System 90 | 17,958
Skin and soft tissues 90 | 18,115
Respiratory system 87 | 17,484

Target Family

Non-IDG 27 | 11,971
Enzyme 25 | 4,146
Ion Channel 25 | 341
Kinase 11 | 634
GPCR 5 | 406
Transporter 1 | 473

KEGG Pathway

Morphine addiction 94 | 94
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 Tchem Ion Channel -1.68717 47.7 33
Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B Tclin Ion Channel -2.21210 162.9 67
Gamma-aminobutyric acid receptor subunit rho-1 GABRR1 Tchem Ion Channel -1.70715 50.4 134
Beta-arrestin-1 ARRB1 Tchem Non-IDG -2.54226 366.3 416
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.23686 16.0 235
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.58202 42.2 123
Mu-type opioid receptor OPRM1 Tclin GPCR -3.20440 1609.2 372
cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B Tclin Enzyme -2.10700 124.5 270
G protein-activated inward rectifier potassium channel 4 KCNJ5 Tchem Ion Channel -2.24687 186.6 114
G protein-activated inward rectifier potassium channel 1 KCNJ3 Tchem Ion Channel -2.31340 205.5 237