Development Level

Tclin 37 | 613
Tbio 32 | 11,445
Tchem 20 | 1,598
Tdark 5 | 6,588

Collection

RFA-RM-18-021 5 | 328
Ion Channel: IDG Consortium (T... 4 | 99
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal bone structure 5 | 187
increased startle reflex 5 | 112
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
hyperactivity 4 | 148
increased heart weight 4 | 62
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
decreased bone mineral content 2 | 151
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
enlarged heart 2 | 210
increased circulating triglyce... 2 | 42
thrombocytopenia 2 | 56
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating iron lev... 1 | 32
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
preweaning lethality, complete... 1 | 979
small kidney 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 75 | 11,493
medulloblastoma, large-cell 63 | 6,241
glioblastoma 56 | 5,792
atypical teratoid / rhabdoid tumor 54 | 5,112
ependymoma 49 | 4,679
ovarian cancer 44 | 8,520
primitive neuroectodermal tumor 44 | 3,035
Astrocytoma, Pilocytic 43 | 3,081
osteosarcoma 42 | 7,950
adult high grade glioma 41 | 3,801
group 3 medulloblastoma 38 | 4,104
oligodendroglioma 38 | 2,850
astrocytic glioma 37 | 2,597
psoriasis 34 | 6,694
lung carcinoma 32 | 2,843
Kidney cancer 30 | 2,613
Schizophrenia 30 | 1,160
invasive ductal carcinoma 28 | 2,951
subependymal giant cell astrocytoma 27 | 2,287
Breast cancer 26 | 3,578
Epilepsy 24 | 792
lung cancer 24 | 4,740
pituitary cancer 23 | 1,972
Pick disease 22 | 1,894
Alcoholic Intoxication, Chronic 21 | 289
Bipolar Disorder 21 | 666
Depressive disorder 21 | 409
Anxiety 20 | 136
Autistic Disorder 18 | 364
interstitial cystitis 18 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
malignant mesothelioma 18 | 3,232
non-small cell lung cancer 18 | 2,890
General anesthesia 17 | 53
Mental Depression 17 | 333
Insomnia 16 | 20
Tonic-clonic epilepsy 16 | 47
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
Atrial Fibrillation 15 | 124
breast carcinoma 15 | 1,638
group 4 medulloblastoma 15 | 1,855
pancreatic cancer 15 | 2,398
Myocardial Perfusion Imaging Adjunct 14 | 25
Sedation as Adjunct to Anesthesia 14 | 15
ductal carcinoma in situ 14 | 1,745
lung adenocarcinoma 14 | 2,716
ulcerative colitis 14 | 1,819
Alcohol dependence 13 | 107
Chronic heart failure 13 | 46
Platelet Aggregation Inhibition 13 | 22
Prevention of Cerebral Thrombosis 13 | 29
astrocytoma 12 | 1,146
tuberculosis 12 | 2,010
Dysuria 11 | 26
Intellectual disability 11 | 1,016
Urinary Tract Irritation 11 | 24
diabetes mellitus 11 | 1,728
Liver cancer 10 | 604
Mood Disorders 10 | 184
Obesity 10 | 678
adrenocortical carcinoma 10 | 1,428
colon cancer 10 | 1,478
Hypertensive disease 9 | 292
Local anesthesia 9 | 40
Major Depressive Disorder 9 | 301
Rheumatoid arthritis 9 | 1,191
Spasticity 9 | 26
Substance Withdrawal Syndrome 9 | 55
Acrodysostosis 8 | 12
Alcohol withdrawal delirium 8 | 11
Alcohol withdrawal syndrome 8 | 20
Benzodiazepine Induced Sedation 8 | 8
Benzodiazepine Maintained Anesthesia 8 | 8
Benzodiazepine Toxicity 8 | 8
Cancer 8 | 2,499
Carney complex 8 | 25
Increased Urinary Frequency 8 | 11
Induce Anterograde Amnesia 8 | 9
Irritable bowel syndrome 8 | 60
Nocturia 8 | 9
Preoperative Anxiety 8 | 9
Sedation 8 | 11
Sedation in Intubated Patients 8 | 8
Status Epilepticus 8 | 98
Suprapubic pain 8 | 8
Tetanus 8 | 68
Unipolar Depression 8 | 250
Urgent desire to urinate 8 | 11
Urinary Incontinence 8 | 50
active Crohn's disease 8 | 922
cystic fibrosis 8 | 1,696
Asthma 7 | 385
Brachydactyly 7 | 156
Cushing's syndrome 7 | 48
Panic disorder 7 | 61
Schizoaffective Disorder 7 | 55
pediatric high grade glioma 7 | 1,064
primary Sjogren syndrome 7 | 735
substance-related disorder 7 | 162

Tissue

Endocrine System 90 | 18,159
Nervous System 87 | 16,725
Blood and immune system 84 | 16,909
Digestive Tract 84 | 17,369
Male tissues 83 | 17,142
Skin and soft tissues 83 | 17,230
Female tissues 82 | 17,400
Liver and Pancreas 77 | 16,750
Urinary Tract 76 | 16,678
Respiratory system 74 | 16,393
Cardiovascular System 71 | 15,192

Target Family

Non-IDG 27 | 12,091
Enzyme 25 | 4,145
Ion Channel 25 | 344
Kinase 11 | 634
GPCR 5 | 408
Transporter 1 | 473

KEGG Pathway

Morphine addiction 94 | 94
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

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