Development Level

Tbio 46 | 11,445
Tchem 16 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal behavior 4 | 298
hypoactivity 4 | 132
decreased bone mineral density 2 | 126
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
decreased lean body mass 2 | 135
embryonic lethality prior to t... 2 | 278
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
short tibia 2 | 97
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
aorta dilation 1 | 3
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased circulating potassiu... 1 | 20
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased circulating bilirubi... 1 | 16
increased circulating glucose ... 1 | 24
increased circulating glycerol... 1 | 9
increased erythrocyte cell num... 1 | 39
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality 1 | 28
preweaning lethality, incomple... 1 | 499
prolonged QT interval 1 | 38
shortened QT interval 1 | 4
thrombocytopenia 1 | 56

Disease

ovarian cancer 48 | 8,520
Carcinoma 37 | 11,493
osteosarcoma 33 | 7,950
medulloblastoma, large-cell 31 | 6,241
Cancer 29 | 2,499
glioblastoma 28 | 5,792
lung cancer 21 | 4,740
atypical teratoid / rhabdoid tumor 20 | 5,112
psoriasis 20 | 6,694
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
group 4 medulloblastoma 15 | 1,855
Breast cancer 14 | 3,578
Neurodegenerative disease 14 | 414
adult high grade glioma 14 | 3,801
diabetes mellitus 14 | 1,728
ependymoma 14 | 4,679
primitive neuroectodermal tumor 14 | 3,035
Vascular disease 13 | 319
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
Schizophrenia 11 | 1,160
acute quadriplegic myopathy 11 | 1,158
malignant mesothelioma 11 | 3,232
Amyotrophic lateral sclerosis 10 | 451
dermatomyositis 10 | 966
group 3 medulloblastoma 10 | 4,104
invasive ductal carcinoma 10 | 2,951
oligodendroglioma 10 | 2,850
spina bifida 10 | 1,074
subependymal giant cell astrocytoma 10 | 2,287
Multiple myeloma 9 | 1,332
Stomach Neoplasms 9 | 300
breast carcinoma 9 | 1,638
non-small cell lung cancer 9 | 2,890
pancreatic cancer 9 | 2,398
ulcerative colitis 9 | 1,819
Astrocytoma, Pilocytic 8 | 3,081
Breast Neoplasms 8 | 445
Cell Transformation, Neoplastic 8 | 97
Mammary Neoplasms 8 | 425
Neoplastic Cell Transformation 8 | 89
Parkinson's disease 8 | 392
Renal Cell Carcinoma 8 | 214
Skin Neoplasms 8 | 69
astrocytic glioma 8 | 2,597
astrocytoma 8 | 1,146
ductal carcinoma in situ 8 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
primary pancreatic ductal adenocarcinoma 8 | 1,109
tuberculosis 8 | 2,010
Colonic Neoplasms 7 | 142
Intellectual disability 7 | 1,016
Lung Neoplasms 7 | 232
Carcinoma, Hepatocellular 6 | 228
Carcinoma, Squamous Cell 6 | 110
Depressive disorder 6 | 409
Epilepsy 6 | 792
Heart disease 6 | 306
Hyperreflexia 6 | 209
Kidney cancer 6 | 2,613
Liver carcinoma 6 | 240
Melanoma 6 | 711
Rheumatoid arthritis 6 | 1,191
Squamous cell carcinoma 6 | 129
Toxic encephalopathy 6 | 141
colon cancer 6 | 1,478
Adenoma 5 | 167
Anxiety 5 | 136
Anxiety disease 5 | 113
Autosomal recessive predisposition 5 | 1,442
Brain Ischemia 5 | 110
Colorectal Neoplasms 5 | 243
Cryptorchidism 5 | 296
Dull intelligence 5 | 645
Dysarthria 5 | 192
Fatigue 5 | 182
Hemangioma 5 | 69
Hepatomegaly 5 | 285
Hypertension 5 | 396
Hypertensive disease 5 | 292
Liver Neoplasms, Experimental 5 | 59
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Neoplasm Invasiveness 5 | 161
Nerve Degeneration 5 | 121
Noonan syndrome 5 | 34
Osteoporosis 5 | 363
Pick disease 5 | 1,894
Poor school performance 5 | 645
Seizures 5 | 596
Waldenstrons macroglobulinemia 5 | 765
juvenile dermatomyositis 5 | 1,187
lung carcinoma 5 | 2,843
pituitary cancer 5 | 1,972
aldosterone-producing adenoma 4 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
fibroadenoma 4 | 559
hepatocellular carcinoma 4 | 547
lung adenocarcinoma 4 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962

Tissue

Digestive Tract 64 | 17,369
Endocrine System 64 | 18,159
Female tissues 64 | 17,400
Male tissues 64 | 17,142
Nervous System 64 | 16,725
Respiratory system 64 | 16,393
Skin and soft tissues 64 | 17,230
Urinary Tract 64 | 16,678
Blood and immune system 63 | 16,909
Liver and Pancreas 63 | 16,750
Cardiovascular System 62 | 15,192

Target Family

Non-IDG 27 | 12,091
Enzyme 15 | 4,145
Kinase 12 | 634
Transcription Factor 11 | 1,400

KEGG Pathway

Mitophagy - animal 65 | 65
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beclin-2 BECN2 Tbio Non-IDG 0.00000 87
Tax1-binding protein 1 TAX1BP1 Tbio Non-IDG -1.44609 30.4 133
Ubiquitin carboxyl-terminal hydrolase 15 USP15 Tbio Enzyme -1.64742 41.6 242
FUN14 domain-containing protein 1 FUNDC1 Tbio Non-IDG -1.21206 16.0 151
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248