Development Level

Tbio 30 | 10,625
Tclin 10 | 602
Tchem 9 | 1,890
Tdark 3 | 7,003

IMPC Phenotype

preweaning lethality, complete... 4 | 633
decreased lean body mass 2 | 195
decreased total body fat amoun... 2 | 186
embryonic lethality prior to t... 2 | 187
short tibia 2 | 82
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal seminal vesicle morph... 1 | 47
abnormal vibrissa morphology 1 | 17
absent vibrissae 1 | 14
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 33
decreased circulating glucose ... 1 | 121
decreased circulating triglyce... 1 | 83
decreased heart weight 1 | 44
decreased leukocyte cell numbe... 1 | 54
enlarged epididymis 1 | 27
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
increased caudal vertebrae num... 1 | 8
increased circulating triglyce... 1 | 24
long tibia 1 | 13
preweaning lethality, incomple... 1 | 260

Disease

ovarian cancer 32 | 8,491
medulloblastoma, large-cell 24 | 6,234
osteosarcoma 24 | 7,933
psoriasis 24 | 6,685
lung cancer 21 | 4,473
ulcerative colitis 21 | 2,087
non-small cell lung cancer 20 | 2,798
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
cystic fibrosis 18 | 1,670
glioblastoma 18 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
lung adenocarcinoma 18 | 2,714
pancreatic cancer 18 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
malignant mesothelioma 15 | 3,163
atypical teratoid/rhabdoid tumor 14 | 1,095
colon cancer 14 | 1,475
Breast cancer 13 | 3,098
lung carcinoma 13 | 2,844
pituitary cancer 13 | 1,972
primitive neuroectodermal tumor 13 | 3,031
atypical teratoid / rhabdoid tumor 12 | 4,369
invasive ductal carcinoma 12 | 2,950
subependymal giant cell astrocytoma 12 | 2,287
Endometriosis 10 | 535
acute quadriplegic myopathy 10 | 1,157
ependymoma 10 | 2,514
primary pancreatic ductal adenocarcinoma 10 | 1,271
Congestive heart failure 9 | 36
Hypertension 9 | 293
Pick disease 9 | 1,893
active Crohn's disease 9 | 918
adrenocortical carcinoma 9 | 1,427
pediatric high grade glioma 9 | 2,712
sonic hedgehog group medulloblastoma 9 | 1,482
tuberculosis 9 | 1,563
Atrial Fibrillation 8 | 110
Cancer 8 | 2,346
Chronic heart failure 8 | 46
Poisoning by digitalis glycoside 8 | 8
adult high grade glioma 8 | 2,148
group 3 medulloblastoma 8 | 2,254
oligodendroglioma 8 | 2,849
pilocytic astrocytoma 8 | 3,086
Anemia 7 | 252
Carcinoma 7 | 2,147
Hypertensive disease 7 | 193
Parkinson's disease 7 | 364
ductal carcinoma in situ 7 | 1,745
interstitial cystitis 7 | 2,299
Diarrhea 6 | 155
Duchenne muscular dystrophy 6 | 602
Hemochromatosis 6 | 55
astrocytic glioma 6 | 2,241
breast carcinoma 6 | 1,614
diabetes mellitus 6 | 1,663
group 4 medulloblastoma 6 | 1,875
inflammatory breast cancer 6 | 404
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
Aceruloplasminemia 5 | 17
Neoplasm Invasiveness 5 | 127
Obesity 5 | 616
astrocytoma 5 | 1,493
esophageal adenocarcinoma 5 | 737
head and neck cancer 5 | 270
medulloblastoma 5 | 1,524
nephrosclerosis 5 | 329
Atopic dermatitis 4 | 944
Down syndrome 4 | 548
Kidney disease 4 | 397
Prostate cancer 4 | 172
Rheumatoid Arthritis 4 | 1,170
Schnyder Corneal Dystrophy 4 | 24
cutaneous lupus erythematosus 4 | 1,056
Adenoma 3 | 165
Arthritis 3 | 248
Atransferrinemia 3 | 8
Diastrophic dysplasia 3 | 21
Heart conduction disease 3 | 65
Heart disease 3 | 279
Hepatitis, Chronic 3 | 22
Inflammatory bowel disease 3 | 142
Liver disease 3 | 219
Liver neoplasms 3 | 108
Multiple myeloma 3 | 1,327
Myocardial Ischemia 3 | 169
Neurodegenerative disease 3 | 383
Osteoporosis 3 | 259
Prostatic Neoplasms 3 | 471
Rickets 3 | 42
Seizures 3 | 95
acute myeloid leukemia 3 | 785
aldosterone-producing adenoma 3 | 664
dermatomyositis 3 | 966
facioscapulohumeral dystrophy 3 | 286
gastric carcinoma 3 | 832
glioblastoma multiforme 3 | 347
hepatocellular carcinoma 3 | 550
mucosa-associated lymphoid tissue lymphoma 3 | 480
pancreatic carcinoma 3 | 567

Tissue

Digestive Tract 52 | 18,472
Endocrine System 52 | 18,511
Female tissues 52 | 18,646
Nervous System 52 | 18,560
Urinary Tract 52 | 18,443
Cardiovascular System 51 | 17,957
Liver and Pancreas 51 | 18,135
Male tissues 51 | 17,968
Skin and soft tissues 51 | 18,114
Blood and immune system 49 | 17,994
Respiratory system 49 | 17,483

Target Family

Transporter 23 | 473
Non-IDG 16 | 11,969
Enzyme 7 | 4,146
Ion Channel 4 | 341
Kinase 1 | 634
Nuclear Receptor 1 | 48

KEGG Pathway

Mineral absorption 52 | 52
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit beta-3 ATP1B3 Tclin Transporter -1.08214 10.9 189
Sodium/potassium-transporting ATPase subunit beta-2 ATP1B2 Tclin Transporter -1.33849 19.3 155
Solute carrier family 26 member 6 SLC26A6 Tbio Ion Channel -1.85864 67.8 85
Chloride channel protein 2 CLCN2 Tclin Ion Channel -2.01977 99.4 191
Transient receptor potential cation channel subfamily M member 6 TRPM6 Tchem Kinase -2.14001 138.4 95
Metallothionein-1F MT1F Tbio Non-IDG -1.13298 14.0 4
Metallothionein-1A MT1A Tbio Non-IDG -1.99723 95.9 34
Metallothionein-1E MT1E Tbio Non-IDG -1.42780 40.1 28
Protein ATP1B4 ATP1B4 Tdark Transporter -0.67056 3.14 30
Sodium-dependent phosphate transport protein 2B SLC34A2 Tbio Transporter -2.02038 86.8 57