Development Level

Tbio 32 | 11,651
Tclin 10 | 612
Tchem 7 | 1,388
Tdark 2 | 6,593

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
abnormal embryo size 2 | 220
abnormal seminal vesicle morph... 2 | 114
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal coat appearance 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal hindbrain development 1 | 16
abnormal hindbrain morphology 1 | 10
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
decreased bone mineral content 1 | 151
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased monocyte cell number 1 | 8
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased circulating HDL chol... 1 | 80
increased circulating triglyce... 1 | 42
long tibia 1 | 25
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 32 | 8,520
Carcinoma 27 | 11,493
atypical teratoid / rhabdoid tumor 25 | 5,112
medulloblastoma, large-cell 24 | 6,241
osteosarcoma 23 | 7,950
psoriasis 23 | 6,694
group 3 medulloblastoma 22 | 4,104
lung cancer 20 | 4,740
Breast cancer 19 | 3,578
cystic fibrosis 19 | 1,696
glioblastoma 19 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
non-small cell lung cancer 19 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
lung adenocarcinoma 18 | 2,716
ulcerative colitis 18 | 1,819
malignant mesothelioma 17 | 3,232
pancreatic cancer 17 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,989
adult high grade glioma 14 | 3,801
colon cancer 14 | 1,478
pituitary cancer 13 | 1,972
primitive neuroectodermal tumor 13 | 3,035
Hypertension 12 | 396
invasive ductal carcinoma 12 | 2,951
lung carcinoma 12 | 2,843
subependymal giant cell astrocytoma 12 | 2,287
ependymoma 11 | 4,679
Autosomal recessive predisposition 10 | 1,442
Congestive heart failure 10 | 113
Endometriosis 10 | 540
acute quadriplegic myopathy 10 | 1,158
primary pancreatic ductal adenocarcinoma 10 | 1,109
Cancer 9 | 2,499
Pick disease 9 | 1,894
active Crohn's disease 9 | 922
adrenocortical carcinoma 9 | 1,428
tuberculosis 9 | 2,010
Anemia 8 | 365
Astrocytoma, Pilocytic 8 | 3,081
Atrial Fibrillation 8 | 124
Chronic heart failure 8 | 46
Kidney cancer 8 | 2,613
Poisoning by digitalis glycoside 8 | 8
oligodendroglioma 8 | 2,850
Hypertensive disease 7 | 292
diabetes mellitus 7 | 1,728
ductal carcinoma in situ 7 | 1,745
interstitial cystitis 7 | 2,312
Diarrhea 6 | 253
Duchenne muscular dystrophy 6 | 601
Hemochromatosis 6 | 54
Parkinson's disease 6 | 392
astrocytic glioma 6 | 2,597
breast carcinoma 6 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Aceruloplasminemia 5 | 16
Atopic dermatitis 5 | 952
Epilepsy 5 | 792
Kidney disease 5 | 430
Liver Cirrhosis, Experimental 5 | 769
Neoplasm Invasiveness 5 | 161
Obesity 5 | 678
Seizures 5 | 596
active ulcerative colitis 5 | 764
astrocytoma 5 | 1,146
esophageal adenocarcinoma 5 | 737
head and neck cancer 5 | 271
nephrosclerosis 5 | 333
Bipolar Disorder 4 | 666
Cerebellar Ataxia 4 | 304
Down syndrome 4 | 499
Failure to gain weight 4 | 365
Intellectual disability 4 | 1,016
Neurodegenerative disease 4 | 414
Osteoporosis 4 | 363
Pediatric failure to thrive 4 | 365
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
Schnyder Corneal Dystrophy 4 | 23
cutaneous lupus erythematosus 4 | 1,057
Adenoma 3 | 167
Arthritis 3 | 290
Dementia 3 | 175
Depressive disorder 3 | 409
Dystonia 3 | 164
Dystonic disease 3 | 106
Heart disease 3 | 306
Inflammatory bowel disease 3 | 151
Liver neoplasms 3 | 130
Mesothelioma, Malignant 3 | 105
Myocardial Ischemia 3 | 169
Neonatal Jaundice 3 | 30
Prostate cancer 3 | 175
Status Epilepticus 3 | 98
aldosterone-producing adenoma 3 | 665
dermatomyositis 3 | 966
hepatocellular carcinoma 3 | 547
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064

Tissue

Digestive Tract 50 | 17,369
Endocrine System 50 | 18,159
Skin and soft tissues 50 | 17,230
Liver and Pancreas 49 | 16,750
Male tissues 49 | 17,142
Blood and immune system 48 | 16,909
Nervous System 48 | 16,725
Urinary Tract 48 | 16,678
Female tissues 47 | 17,400
Respiratory system 46 | 16,393
Cardiovascular System 45 | 15,192

Target Family

Transporter 22 | 473
Non-IDG 16 | 12,091
Enzyme 7 | 4,145
Ion Channel 4 | 344
Kinase 1 | 634
Nuclear Receptor 1 | 48

KEGG Pathway

Mineral absorption 51 | 51
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Protein ATP1B4 ATP1B4 Tdark Transporter -0.67056 4.78 35
Metallothionein-1F MT1F Tbio Non-IDG -1.17171 15.1 11
Sodium/potassium-transporting ATPase subunit beta-2 ATP1B2 Tclin Transporter -1.36427 23.9 176
Zinc transporter ZIP4 SLC39A4 Tbio Transporter -2.05142 112.2 124
Ferritin heavy chain FTH1 Tbio Non-IDG -3.00480 982.1 562
Sodium/potassium-transporting ATPase subunit beta-3 ATP1B3 Tclin Transporter -1.10090 13.3 226
Cytochrome b reductase 1 CYBRD1 Tbio Enzyme -1.81134 60.3 74
Solute carrier family 40 member 1 SLC40A1 Tchem Transporter -2.48227 289.8 169
Sodium/potassium-transporting ATPase subunit beta-1 ATP1B1 Tclin Transporter -1.40091 23.3 207