Development Level

Tbio 68 | 11,445
Tchem 37 | 1,598
Tclin 25 | 613
Tdark 3 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

decreased mean corpuscular vol... 5 | 79
preweaning lethality, complete... 5 | 979
decreased circulating creatini... 3 | 39
decreased vertical activity 3 | 208
embryonic lethality prior to t... 3 | 278
hyperactivity 3 | 148
increased hemoglobin content 3 | 45
increased mean corpuscular hem... 3 | 96
increased neutrophil cell numb... 3 | 46
male infertility 3 | 123
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased body weight 2 | 161
decreased heart weight 2 | 27
decreased lymphocyte cell numb... 2 | 83
embryonic lethality prior to o... 2 | 239
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
female infertility 2 | 60
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 36
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal colon morphology 1 | 3
abnormal cornea morphology 1 | 31
abnormal duodenum morphology 1 | 4
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal glucose homeostasis 1 | 4
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
edema 1 | 59
enlarged cecum 1 | 5
enlarged uterus 1 | 11
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
short tibia 1 | 97
small testis 1 | 58
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 88 | 11,493
Cancer 82 | 2,499
ovarian cancer 71 | 8,520
psoriasis 71 | 6,694
lung cancer 65 | 4,740
osteosarcoma 57 | 7,950
glioblastoma 54 | 5,792
medulloblastoma, large-cell 48 | 6,241
malignant mesothelioma 42 | 3,232
Rheumatoid arthritis 37 | 1,191
tuberculosis 35 | 2,010
atypical teratoid / rhabdoid tumor 34 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 34 | 3,291
Multiple Sclerosis 33 | 540
cutaneous lupus erythematosus 33 | 1,057
interstitial cystitis 30 | 2,312
lung carcinoma 30 | 2,843
Breast cancer 29 | 3,578
cystic fibrosis 29 | 1,696
ependymoma 29 | 4,679
Schizophrenia 28 | 1,160
pancreatic cancer 28 | 2,398
subependymal giant cell astrocytoma 28 | 2,287
Influenza 27 | 142
adult high grade glioma 27 | 3,801
invasive ductal carcinoma 27 | 2,951
ulcerative colitis 27 | 1,819
Kidney cancer 26 | 2,613
lung adenocarcinoma 26 | 2,716
Astrocytoma, Pilocytic 25 | 3,081
juvenile dermatomyositis 25 | 1,187
Arthritis 24 | 290
Hypersensitivity reaction type II disease 24 | 253
diabetes mellitus 23 | 1,728
Multiple myeloma 22 | 1,332
oligodendroglioma 22 | 2,850
Asthma 21 | 385
dermatomyositis 21 | 966
group 4 medulloblastoma 21 | 1,855
Anemia 20 | 365
Autosomal recessive predisposition 20 | 1,442
Inflammatory bowel disease 20 | 151
Prostatic Neoplasms 20 | 495
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,989
primary Sjogren syndrome 20 | 735
primitive neuroectodermal tumor 20 | 3,035
Breast Neoplasms 19 | 445
Systemic lupus erythematosus 19 | 194
non-small cell lung cancer 19 | 2,890
group 3 medulloblastoma 18 | 4,104
Mammary Neoplasms 17 | 425
astrocytoma 17 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
Arthritis, Rheumatoid 16 | 174
Fever 16 | 138
Immunologic Deficiency Syndromes 16 | 113
Inflammation 16 | 120
Lung Neoplasms 16 | 232
pituitary cancer 16 | 1,972
Pneumonia 15 | 174
colon cancer 15 | 1,478
Atopic dermatitis 14 | 952
Hepatitis B 14 | 108
Hepatitis C 14 | 94
Major Depressive Disorder 14 | 301
Splenomegaly 14 | 190
Vascular disease 14 | 319
breast carcinoma 14 | 1,638
ductal carcinoma in situ 14 | 1,745
hepatocellular carcinoma 14 | 547
nasopharyngeal carcinoma 14 | 1,058
Bipolar Disorder 13 | 666
Diarrhea 13 | 253
Hepatitis 13 | 67
Kidney disease 13 | 430
Liver carcinoma 13 | 240
Melanoma 13 | 711
Microphthalmia with limb anomalies 13 | 40
Myocardial Ischemia 13 | 169
Squamous cell carcinoma 13 | 129
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Allergic hypersensitivity disease 12 | 126
Carcinoma, Hepatocellular 12 | 228
Carcinoma, Squamous Cell 12 | 110
Encephalitis 12 | 64
Human immunodeficiency virus infectious disease 12 | 138
Liver Cirrhosis, Experimental 12 | 769
Lung disease 12 | 142
Meningitis 12 | 67
Stomach Neoplasms 12 | 300
Unipolar Depression 12 | 250
pancreatic carcinoma 12 | 562
Brain Ischemia 11 | 110
Depressive disorder 11 | 409
Dermatitis 11 | 157
Malaria 11 | 160
Pick disease 11 | 1,894
Seizures 11 | 596
Vasculitis 11 | 80
astrocytic glioma 11 | 2,597

Tissue

Blood and immune system 121 | 16,909
Male tissues 120 | 17,142
Digestive Tract 119 | 17,369
Skin and soft tissues 119 | 17,230
Urinary Tract 119 | 16,678
Endocrine System 118 | 18,159
Female tissues 118 | 17,400
Respiratory system 118 | 16,393
Liver and Pancreas 117 | 16,750
Nervous System 116 | 16,725
Cardiovascular System 109 | 15,192

Target Family

Non-IDG 76 | 12,091
Kinase 31 | 634
Enzyme 13 | 4,145
Transcription Factor 12 | 1,400
GPCR 1 | 408

KEGG Pathway

Measles 133 | 133
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
2'-5'-oligoadenylate synthase 3 OAS3 Tbio Enzyme -1.30083 17.8 141
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Heat shock-related 70 kDa protein 2 HSPA2 Tbio Non-IDG -1.98655 104.3 162
Interferon alpha-1/13 IFNA13 Tbio Non-IDG -3.87160 7663.4 500
Interferon alpha-17 IFNA17 Tbio Non-IDG -2.39299 231.1 56
Heat shock 70 kDa protein 1A HSPA1B Tchem Non-IDG -3.10995 0.00000 1174
Heat shock 70 kDa protein 1B HSPA1B Tbio Non-IDG -1.61862 0.00000 60
Toll-like receptor 7 TLR7 Tclin Non-IDG -3.02761 1078.4 759
Membrane cofactor protein CD46 Tbio Non-IDG -2.94025 875.6 770