Development Level

Tbio 22 | 11,445
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal placenta size 1 | 20
decreased circulating alanine ... 1 | 47
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 17 | 11,493
Congenital muscular dystrophy 13 | 29
Walker-Warburg syndrome 13 | 20
Lissencephaly 12 | 69
Muscular dystrophy 12 | 75
Walker-Warburg congenital muscular dystrophy 12 | 14
osteosarcoma 10 | 7,950
Hydrocephalus 9 | 152
glioblastoma 9 | 5,792
ovarian cancer 9 | 8,520
Autosomal recessive predisposition 8 | 1,442
MUSCULAR DYSTROPHY, CONGENITAL, 1C 8 | 9
medulloblastoma, large-cell 8 | 6,241
Cobblestone Lissencephaly 7 | 8
Creatine phosphokinase serum increased 7 | 110
Elevated creatine kinase 7 | 110
Epilepsy 7 | 792
Intellectual disability 7 | 1,016
Muscle biopsy shows dystrophic changes 7 | 39
Muscle eye brain disease 7 | 8
Muscle-eye-brain disease 7 | 8
Myopathy 7 | 185
Retinal Dysplasia 7 | 11
limb-girdle muscular dystrophy 7 | 37
Cerebellar Hypoplasia 6 | 61
Cerebellar dysplasia 6 | 8
Cognitive delay 6 | 608
Dandy-Walker Syndrome 6 | 39
Global developmental delay 6 | 608
Hypoplasia of the brainstem 6 | 22
Hypotonia, severe 6 | 33
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION), TYPE B, 1 6 | 7
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION), TYPE B, 14 6 | 7
MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION), TYPE B, 2 6 | 7
Mental and motor retardation 6 | 608
Muscle hypotonia 6 | 571
Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain and Eye Anomalies), Type A, 1 6 | 6
Seizures 6 | 596
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
Abnormality of the voice 5 | 46
Abnormally small eyeball 5 | 97
Agenesis of corpus callosum 5 | 83
Atrophic retina 5 | 7
Blind Vision 5 | 111
Blindness, Legal 5 | 110
Cataract 5 | 297
Congenital keratoglobus 5 | 14
Congenital muscular dystrophy (disorder) 5 | 14
Congenital ocular coloboma (disorder) 5 | 40
Corneal diameter increased 5 | 13
Decreased size of eyeball 5 | 97
Dull intelligence 5 | 645
Electroencephalogram abnormal 5 | 101
Electromyogram abnormal 5 | 49
Gait abnormality 5 | 135
Glaucoma 5 | 239
Globe of eye large 5 | 20
Highly variable clinical phenotype 5 | 150
Highly variable phenotype and severity 5 | 150
Highly variable phenotype, even within families 5 | 150
Hydrophthalmos 5 | 19
Impaired cognition 5 | 96
Lens Opacities 5 | 231
Low Vision 5 | 174
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Mental impairment 5 | 95
Microphthalmos 5 | 100
Motor delay 5 | 147
Muscle Hypertonia 5 | 88
Myopia 5 | 176
No development of motor milestones 5 | 147
Optic Atrophy 5 | 242
Pachygyria 5 | 41
Phenotypic variability 5 | 150
Polymicrogyria 5 | 48
Poor school performance 5 | 645
Profound Mental Retardation 5 | 31
Profound intellectual disabilities 5 | 31
Retinal Degeneration 5 | 106
Severe mental retardation (I.Q. 20-34) 5 | 99
Small head 5 | 374
Speech Disorders 5 | 58
Strabismus 5 | 270
Visual Impairment 5 | 174
ependymoma 5 | 4,679
malignant mesothelioma 5 | 3,232
psoriasis 5 | 6,694
Contracture 4 | 96
Contracture of joint 4 | 93
Corneal Opacity 4 | 53
Infantile onset 4 | 238
Kidney cancer 4 | 2,613
Uranostaphyloschisis 4 | 167
lung cancer 4 | 4,740
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
subependymal giant cell astrocytoma 4 | 2,287

Tissue

Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Urinary Tract 23 | 16,678
Blood and immune system 22 | 16,909
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Cardiovascular System 21 | 15,192

Target Family

Enzyme 19 | 4,145
Non-IDG 3 | 12,091
Kinase 1 | 634

KEGG Pathway

Mannose type O-glycan biosynth... 23 | 23
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Protein O-mannosyl-transferase 1 POMT1 Tbio Enzyme -1.57372 38.3 123
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 B3GALNT2 Tbio Enzyme -1.06354 9.47 78
D-ribitol-5-phosphate cytidylyltransferase ISPD Tbio Enzyme -2.15479 145.9 72
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 POMGNT1 Tbio Enzyme -2.17085 153.6 69
Fukutin FKTN Tbio Non-IDG -2.34994 236.9 131
Alpha-(1,3)-fucosyltransferase 4 FUT4 Tbio Enzyme -3.11231 1234.9 1016
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B MGAT5B Tbio Enzyme -0.99363 12.8 34
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 B3GAT1 Tbio Enzyme -2.94091 860.2 882
Beta-1,4-galactosyltransferase 2 B4GALT2 Tbio Enzyme -0.88995 7.16 122