Development Level

Tbio 83 | 10,625
Tchem 32 | 1,890
Tdark 6 | 7,003
Tclin 2 | 602

IMPC Term

decreased total body fat amoun... 7 | 186
increased bone mineral content 5 | 92
abnormal bone structure 4 | 131
increased bone mineral density 4 | 52
increased circulating alkaline... 4 | 119
increased lean body mass 4 | 107
abnormal behavior 3 | 226
decreased body length 3 | 108
decreased bone mineral density 3 | 126
decreased circulating serum al... 3 | 79
enlarged lymph nodes 3 | 27
hypoactivity 3 | 89
increased or absent threshold ... 3 | 128
preweaning lethality, complete... 3 | 633
preweaning lethality, incomple... 3 | 260
short tibia 3 | 82
thrombocytosis 3 | 23
abnormal kidney morphology 2 | 30
cardiovascular system phenotyp... 2 | 35
decreased erythrocyte cell num... 2 | 43
decreased heart rate 2 | 10
decreased lean body mass 2 | 195
decreased prepulse inhibition 2 | 52
decreased rib number 2 | 59
decreased total retina thickne... 2 | 20
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
increased circulating potassiu... 2 | 31
increased prepulse inhibition 2 | 21
increased startle reflex 2 | 38
small adrenal glands 2 | 15
straub tail 2 | 26
abnormal behavioral response t... 1 | 52
abnormal coat/hair pigmentatio... 1 | 54
abnormal embryo size 1 | 112
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 51
abnormal hindbrain development 1 | 24
abnormal lens morphology 1 | 73
abnormal lung morphology 1 | 15
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal inner nuclear... 1 | 5
abnormal retinal vasculature m... 1 | 15
abnormal sensory capabilities/... 1 | 3
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal vibrissa morphology 1 | 17
abnormal vitreous body morphol... 1 | 7
decreased B cell number 1 | 30
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased Ly6C low monocyte nu... 1 | 23
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased basophil cell number 1 | 11
decreased bone mineral content 1 | 157
decreased cardiac output 1 | 2
decreased caudal vertebrae num... 1 | 49
decreased circulating bilirubi... 1 | 14
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased grip strength 1 | 123
decreased heart rate variabili... 1 | 11
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased monocyte cell number 1 | 28
decreased respiratory quotient 1 | 12
decreased vertical activity 1 | 22
enlarged spleen 1 | 26
enlarged urinary bladder 1 | 4
female infertility 1 | 34
herniated abdominal wall 1 | 4
hydrops fetalis 1 | 22
hyperactivity 1 | 108
impaired glucose tolerance 1 | 52
impaired pupillary reflex 1 | 14
improved glucose tolerance 1 | 56
increased B cell number 1 | 23
increased blood urea nitrogen ... 1 | 44
increased cardiac muscle contr... 1 | 5
increased circulating HDL chol... 1 | 63
increased circulating aspartat... 1 | 17
increased erythrocyte cell num... 1 | 26
increased fasted circulating g... 1 | 68
increased gamma-delta T cell n... 1 | 16
increased heart weight 1 | 37
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular hem... 1 | 93
increased mean corpuscular hem... 1 | 25
increased sacral vertebrae num... 1 | 62
limb grasping 1 | 35
polydactyly 1 | 22
premature death 1 | 5
prolonged QT interval 1 | 3

Disease

ovarian cancer 82 | 8,484
osteosarcoma 59 | 7,933
glioblastoma 58 | 5,572
medulloblastoma, large-cell 49 | 6,234
psoriasis 43 | 6,685
malignant mesothelioma 38 | 3,162
atypical teratoid / rhabdoid tumor 36 | 4,369
lung cancer 36 | 4,466
pilocytic astrocytoma 32 | 3,086
subependymal giant cell astrocytoma 32 | 2,287
Multiple myeloma 29 | 1,327
tuberculosis 28 | 1,557
diabetes mellitus 27 | 1,663
lung carcinoma 27 | 2,844
pediatric high grade glioma 27 | 2,712
astrocytoma 24 | 1,493
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
invasive ductal carcinoma 22 | 2,950
Neurodegenerative disease 21 | 383
ependymoma 21 | 2,514
group 4 medulloblastoma 20 | 1,875
Cancer 19 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
pancreatic cancer 18 | 2,300
ulcerative colitis 18 | 2,087
Pick disease 17 | 1,893
dermatomyositis 17 | 933
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
non-small cell lung cancer 17 | 2,798
primitive neuroectodermal tumor 17 | 3,031
Mucopolysaccharidosis 16 | 24
adult high grade glioma 16 | 2,148
Breast cancer 15 | 3,094
acute quadriplegic myopathy 15 | 1,157
juvenile dermatomyositis 15 | 1,189
Waldenstrons macroglobulinemia 14 | 765
esophageal adenocarcinoma 14 | 737
lung adenocarcinoma 14 | 2,713
astrocytic glioma 13 | 2,241
medulloblastoma 13 | 1,524
oligodendroglioma 13 | 2,849
Down syndrome 12 | 548
inclusion-cell disease 12 | 15
interstitial cystitis 12 | 2,299
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
posterior fossa group B ependymoma 12 | 1,530
Alzheimer's disease 11 | 644
Duchenne muscular dystrophy 11 | 602
Neuronal ceroid lipofuscinosis 11 | 28
cystic fibrosis 11 | 1,665
primary pancreatic ductal adenocarcinoma 11 | 1,271
Gangliosidosis 10 | 17
Intellectual disability 10 | 573
Rheumatoid Arthritis 10 | 1,160
breast carcinoma 10 | 1,614
cutaneous lupus erythematosus 10 | 1,056
group 3 medulloblastoma 10 | 2,254
Atopic dermatitis 9 | 944
colon cancer 9 | 1,475
mucosa-associated lymphoid tissue lymphoma 9 | 480
pituitary cancer 9 | 1,972
posterior fossa group A ependymoma 9 | 1,511
primary Sjogren syndrome 9 | 789
Carcinoma 8 | 2,147
Gaucher's disease 8 | 24
Glycoproteinosis 8 | 13
IGA Glomerulonephritis 8 | 454
Metachromatic leukodystrophy 8 | 13
Multiple Sclerosis 8 | 498
adrenocortical carcinoma 8 | 1,427
Epilepsy 7 | 346
acute myeloid leukemia 7 | 780
atypical teratoid/rhabdoid tumor 7 | 1,095
progressive supranuclear palsy 7 | 674
Chronic hepatitis C 6 | 12
Fucosidosis 6 | 10
Krabbe disease 6 | 11
Lysosomal storage disease 6 | 11
Osteopetrosis 6 | 40
gastric carcinoma 6 | 832
hereditary spastic paraplegia 6 | 313
pancreatic carcinoma 6 | 567
sarcoidosis 6 | 358
sonic hedgehog group medulloblastoma 6 | 1,482
spina bifida 6 | 1,064
Angiokeratoma 5 | 9
Arthritis 5 | 248
Hermansky-Pudlak syndrome 5 | 43
Leukodystrophy 5 | 30
Neuropathy 5 | 210
Obesity 5 | 616
Osteoporosis 5 | 257
Prostatic Neoplasms 5 | 471
Stomach Neoplasms 5 | 282
Vascular disease 5 | 281
active Crohn's disease 5 | 918
aldosterone-producing adenoma 5 | 664
inflammatory breast cancer 5 | 404
non primary Sjogren syndrome sicca 5 | 840
tuberculosis and treatment for 6 months 5 | 686

Tissue

Blood and immune system 123 | 17,995
Cardiovascular System 123 | 17,958
Digestive Tract 123 | 18,473
Endocrine System 123 | 18,512
Female tissues 123 | 18,647
Liver and Pancreas 123 | 18,136
Male tissues 123 | 17,969
Nervous System 123 | 18,561
Respiratory system 123 | 17,484
Skin and soft tissues 123 | 18,115
Urinary Tract 123 | 18,444

Target Family

Enzyme 68 | 4,146
Non-IDG 48 | 11,971
Transporter 5 | 473
Ion Channel 1 | 341
Transcription Factor 1 | 1,400

KEGG Pathway

Lysosome 123 | 123
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ATP-binding cassette sub-family A member 2 ABCA2 Tbio Transporter -1.41708 32.2 125
Lysosome-associated membrane glycoprotein 2 LAMP2 Tbio Non-IDG -2.51989 315.7 757
V-type proton ATPase 116 kDa subunit a isoform 1 ATP6V0A1 Tbio Enzyme -1.36455 23.7 59
N-acetylgalactosamine-6-sulfatase GALNS Tbio Enzyme -2.40411 261.5 203
Major facilitator superfamily domain-containing protein 8 MFSD8 Tbio Non-IDG -1.80970 69.0 25
Tartrate-resistant acid phosphatase type 5 ACP5 Tbio Enzyme -3.30884 1807.4 259
Palmitoyl-protein thioesterase 1 PPT1 Tbio Enzyme -2.63667 459.4 236
Proactivator polypeptide-like 1 PSAPL1 Tdark Non-IDG 0.00000 64
Lysosome-associated membrane glycoprotein 1 LAMP1 Tbio Non-IDG -2.89124 751.6 788
AP-1 complex subunit beta-1 AP1B1 Tbio Non-IDG -1.51499 33.3 58