Development Level

Tbio 38 | 10,625
Tchem 14 | 1,890
Tdark 6 | 7,003
Tclin 1 | 602

IMPC Term

abnormal behavior 6 | 226
decreased total body fat amoun... 6 | 186
increased grip strength 5 | 83
preweaning lethality, complete... 4 | 633
abnormal retina morphology 3 | 100
decreased body length 3 | 108
decreased bone mineral density 3 | 126
decreased circulating alkaline... 3 | 41
decreased prepulse inhibition 3 | 52
increased lean body mass 3 | 107
abnormal retinal pigmentation 2 | 61
decreased circulating HDL chol... 2 | 77
decreased circulating LDL chol... 2 | 37
decreased circulating choleste... 2 | 85
decreased circulating serum al... 2 | 79
decreased lean body mass 2 | 195
decreased mean corpuscular vol... 2 | 50
hypoactivity 2 | 89
increased bone mineral content 2 | 92
increased circulating triglyce... 2 | 24
increased mean platelet volume 2 | 19
short tibia 2 | 82
abnormal behavioral response t... 1 | 52
abnormal body wall morphology 1 | 7
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal craniofacial morpholo... 1 | 12
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal forebrain morphology 1 | 4
abnormal gait 1 | 51
abnormal hindbrain morphology 1 | 2
abnormal midbrain morphology 1 | 2
abnormal neural tube closure 1 | 37
abnormal pancreas morphology 1 | 6
abnormal response to tactile s... 1 | 16
abnormal retinal inner nuclear... 1 | 5
abnormal seminal vesicle morph... 1 | 47
abnormal skin morphology 1 | 23
abnormal startle reflex 1 | 14
abnormal vertebrae morphology 1 | 14
cardiovascular system phenotyp... 1 | 35
corneal opacity 1 | 25
decreased B cell number 1 | 30
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased T cell number 1 | 31
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating fructosa... 1 | 31
decreased circulating glycerol... 1 | 19
decreased circulating total pr... 1 | 41
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased rib number 1 | 59
enlarged heart 1 | 111
enlarged spleen 1 | 26
hydrometra 1 | 13
impaired pupillary reflex 1 | 14
increased bone mineral density 1 | 52
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating sodium l... 1 | 71
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased neutrophil cell numb... 1 | 15
increased prepulse inhibition 1 | 21
increased red blood cell distr... 1 | 21
increased sacral vertebrae num... 1 | 62
male infertility 1 | 62
preweaning lethality, incomple... 1 | 260
prolonged QRS complex duration 1 | 2
shortened RR interval 1 | 19
small testis 1 | 37
thrombocytopenia 1 | 46
tremors 1 | 34

Disease

ovarian cancer 34 | 8,484
osteosarcoma 32 | 7,933
psoriasis 23 | 6,685
medulloblastoma, large-cell 21 | 6,234
atypical teratoid / rhabdoid tumor 19 | 4,369
malignant mesothelioma 19 | 3,162
Cancer 18 | 2,346
glioblastoma 18 | 5,572
Carcinoma 17 | 2,147
primitive neuroectodermal tumor 16 | 3,031
lung cancer 15 | 4,466
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,795
oligodendroglioma 13 | 2,849
Breast cancer 12 | 3,094
ependymoma 12 | 2,514
invasive ductal carcinoma 12 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
Pick disease 9 | 1,893
acute myeloid leukemia 9 | 780
ductal carcinoma in situ 9 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
non-small cell lung cancer 9 | 2,798
medulloblastoma 8 | 1,524
pilocytic astrocytoma 8 | 3,086
pituitary cancer 8 | 1,972
Rheumatoid Arthritis 7 | 1,160
astrocytic glioma 7 | 2,241
group 3 medulloblastoma 7 | 2,254
interstitial cystitis 7 | 2,299
lung adenocarcinoma 7 | 2,713
pediatric high grade glioma 7 | 2,712
subependymal giant cell astrocytoma 7 | 2,287
Intellectual disability 6 | 573
acute quadriplegic myopathy 6 | 1,157
adult high grade glioma 6 | 2,148
astrocytoma 6 | 1,493
breast carcinoma 6 | 1,614
tuberculosis 6 | 1,557
ulcerative colitis 6 | 2,087
Succinic semialdehyde dehydrogenase deficiency 5 | 16
adrenocortical carcinoma 5 | 1,427
colon cancer 5 | 1,475
cystic fibrosis 5 | 1,665
group 4 medulloblastoma 5 | 1,875
nephrosclerosis 5 | 329
posterior fossa group B ependymoma 5 | 1,530
sonic hedgehog group medulloblastoma 5 | 1,482
spina bifida 5 | 1,064
Leukemia, Myelocytic, Acute 4 | 113
Mammary Neoplasms 4 | 410
Multiple myeloma 4 | 1,327
Stomach Neoplasms 4 | 282
esophageal adenocarcinoma 4 | 737
juvenile dermatomyositis 4 | 1,189
lung carcinoma 4 | 2,844
pancreatic cancer 4 | 2,300
posterior fossa group A ependymoma 4 | 1,511
Adenoid Cystic Carcinoma 3 | 99
Autistic Disorder 3 | 320
Bladder Neoplasm 3 | 109
Degenerative polyarthritis 3 | 93
IGA Glomerulonephritis 3 | 454
Leukemia 3 | 88
Liver carcinoma 3 | 217
Lymphoid leukemia 3 | 69
Male infertility 3 | 170
Sotos syndrome 3 | 13
Squamous cell carcinoma of esophagus 3 | 82
Waldenstrons macroglobulinemia 3 | 765
Weaver syndrome 3 | 6
Wolf-Hirschhorn syndrome 3 | 32
atypical teratoid/rhabdoid tumor 3 | 1,095
diabetes mellitus 3 | 1,663
glioblastoma multiforme 3 | 347
Acquired metabolic disease 2 | 267
Alzheimer's disease 2 | 644
Amyotrophic Lateral Sclerosis 2 | 431
Atopic dermatitis 2 | 944
Carcinoma, Transitional Cell 2 | 31
Chronic obstructive pulmonary disease 2 | 146
Corneal staphyloma 2 | 4
Gaucher disease type 1 2 | 171
Immune system cancer 2 | 38
Kidney disease 2 | 396
Liver disease 2 | 219
Lymphoma, Follicular 2 | 20
Myeloid Leukemia 2 | 19
Orotic aciduria 2 | 16
aldosterone-producing adenoma 2 | 664
beta-ketothiolase deficiency 2 | 13
dermatomyositis 2 | 933
fibroadenoma 2 | 557
gastric carcinoma 2 | 832
hepatocellular carcinoma 2 | 532
inflammatory breast cancer 2 | 404
nasopharyngeal carcinoma 2 | 1,056
primary pancreatic ductal adenocarcinoma 2 | 1,271
substance-related disorder 2 | 105
tuberculosis and treatment for 6 months 2 | 686

Tissue

Digestive Tract 59 | 18,473
Endocrine System 59 | 18,512
Female tissues 59 | 18,647
Liver and Pancreas 59 | 18,136
Nervous System 59 | 18,561
Skin and soft tissues 59 | 18,115
Urinary Tract 59 | 18,444
Blood and immune system 58 | 17,995
Cardiovascular System 58 | 17,958
Male tissues 58 | 17,969
Respiratory system 58 | 17,484

Target Family

Enzyme 26 | 4,146
Epigenetic 25 | 242
TF/Epigenetic 6 | 38
Non-IDG 2 | 11,971

KEGG Pathway

Lysine degradation 59 | 59
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone-lysine N-methyltransferase SETD1B SETD1B Tbio Epigenetic -1.20916 14.6 78
Trifunctional enzyme subunit alpha, mitochondrial HADHA Tbio Non-IDG -2.96515 948.2 132
Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 Tbio Enzyme -3.11277 1238.0 122
Histone-lysine N-methyltransferase SETD1A SETD1A Tbio Epigenetic -2.53375 346.3 108
Histone-lysine N-methyltransferase 2E KMT2E Tbio Epigenetic -1.45323 38.7 150
Procollagen galactosyltransferase 2 COLGALT2 Tbio Enzyme -0.03476 0.96 97
Histone-lysine N-methyltransferase KMT5C KMT5C Tdark Epigenetic 1.18 0.06 42
2-oxoglutarate dehydrogenase-like, mitochondrial OGDHL Tdark Enzyme -0.56427 3.63 42
Procollagen galactosyltransferase 1 COLGALT1 Tdark Enzyme -0.30702 2.22 33
Histone-lysine N-methyltransferase SETMAR SETMAR Tbio Epigenetic -1.30388 25.8 104