Development Level

Tchem 31 | 1,890
Tbio 19 | 10,625
Tclin 13 | 602
Tdark 2 | 7,003

Collection

Eligible Kinase Proteins 2 | 134
Eligible Ion Channel Proteins 1 | 117

IMPC Term

abnormal embryo size 2 | 112
abnormal forebrain development 2 | 18
abnormal hindbrain development 2 | 24
abnormal neural tube closure 2 | 37
abnormal retina morphology 2 | 100
decreased body weight 2 | 174
embryonic lethality prior to t... 2 | 187
hypoactivity 2 | 89
male infertility 2 | 62
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal gait 1 | 51
abnormal lens morphology 1 | 73
abnormal midbrain development 1 | 22
abnormal spleen morphology 1 | 36
abnormal vocalization 1 | 21
cataract 1 | 26
decreased caudal vertebrae num... 1 | 49
decreased circulating alanine ... 1 | 53
decreased circulating bilirubi... 1 | 14
decreased circulating insulin ... 1 | 75
decreased circulating magnesiu... 1 | 11
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased eosinophil cell numb... 1 | 41
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased total body fat amoun... 1 | 186
enlarged heart 1 | 111
enlarged spleen 1 | 26
increased startle reflex 1 | 38
preweaning lethality, complete... 1 | 633
small epididymis 1 | 3
thrombocytopenia 1 | 46

Disease

medulloblastoma, large-cell 38 | 6,234
glioblastoma 36 | 5,572
psoriasis 36 | 6,685
ovarian cancer 34 | 8,484
atypical teratoid / rhabdoid tumor 30 | 4,369
pilocytic astrocytoma 30 | 3,086
osteosarcoma 29 | 7,933
primitive neuroectodermal tumor 26 | 3,031
Carcinoma 24 | 2,147
Cancer 23 | 2,346
oligodendroglioma 23 | 2,849
subependymal giant cell astrocytoma 21 | 2,287
lung cancer 20 | 4,466
pediatric high grade glioma 20 | 2,712
astrocytic glioma 19 | 2,241
ependymoma 19 | 2,514
Breast cancer 18 | 3,094
Pick disease 17 | 1,893
Schizophrenia 17 | 501
adult high grade glioma 16 | 2,148
lung adenocarcinoma 16 | 2,713
lung carcinoma 15 | 2,844
medulloblastoma 15 | 1,524
Intellectual disability 14 | 573
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
astrocytoma 12 | 1,493
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,956
Parkinson's disease 11 | 364
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
malignant mesothelioma 11 | 3,162
Epilepsy 10 | 346
Toxic encephalopathy 10 | 131
colon cancer 10 | 1,475
pancreatic cancer 10 | 2,300
posterior fossa group A ependymoma 10 | 1,511
Autistic Disorder 9 | 320
Cocaine-Related Disorders 9 | 88
Melanoma 9 | 261
Multiple myeloma 9 | 1,327
Rheumatoid Arthritis 9 | 1,160
group 3 medulloblastoma 9 | 2,254
group 4 medulloblastoma 9 | 1,875
pituitary cancer 9 | 1,972
ulcerative colitis 9 | 2,087
Alzheimer's disease 8 | 644
Noonan Syndrome 8 | 33
Waldenstrons macroglobulinemia 8 | 765
atypical teratoid/rhabdoid tumor 8 | 1,095
invasive ductal carcinoma 8 | 2,950
non-small cell lung cancer 8 | 2,798
Amyotrophic Lateral Sclerosis 7 | 431
General anesthesia 7 | 53
Heart disease 7 | 279
Local anesthesia 7 | 40
Obesity 7 | 616
Substance Withdrawal Syndrome 7 | 52
Vascular disease 7 | 281
cystic fibrosis 7 | 1,665
juvenile dermatomyositis 7 | 1,189
non-small cell lung carcinoma 7 | 413
sonic hedgehog group medulloblastoma 7 | 1,482
Bipolar Disorder 6 | 266
Colorectal Neoplasms 6 | 217
Hyperalgesia 6 | 71
Kidney cancer 6 | 118
Lung Neoplasms 6 | 171
tuberculosis 6 | 1,557
Alcoholism 5 | 14
Arteriosclerotic Parkinsonism 5 | 8
Cardio-facio-cutaneous syndrome 5 | 6
Cardiofaciocutaneous syndrome 5 | 15
Cardiomyopathy 5 | 110
Costello syndrome (disorder) 5 | 7
Crohn's disease 5 | 304
Extrapyramidal disease 5 | 8
Influenza A Prevention 5 | 7
Influenza due to Influenza A virus 5 | 7
Major Depressive Disorder 5 | 106
Mammary Neoplasms 5 | 410
Parkinsonism 5 | 19
Postencephalitic parkinsonism 5 | 12
Prostatic Neoplasms 5 | 471
Stomach Neoplasms 5 | 282
diabetes mellitus 5 | 1,663
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
posterior fossa group B ependymoma 5 | 1,530
spina bifida 5 | 1,064
tuberculosis and treatment for 3 months 5 | 327
Adenoid Cystic Carcinoma 4 | 99
Bladder Neoplasm 4 | 109
Brain Ischemia 4 | 87
Cerebrovascular disease 4 | 231
Huntington's disease 4 | 72
Lennox-Gastaut syndrome 4 | 34
Liver carcinoma 4 | 217
Neurodegenerative disease 4 | 383
acute quadriplegic myopathy 4 | 1,157
esophageal adenocarcinoma 4 | 737
nasopharyngeal carcinoma 4 | 1,056
primary pancreatic ductal adenocarcinoma 4 | 1,271

Tissue

Blood and immune system 65 | 17,995
Cardiovascular System 65 | 17,958
Digestive Tract 65 | 18,473
Endocrine System 65 | 18,512
Female tissues 65 | 18,647
Liver and Pancreas 65 | 18,136
Male tissues 65 | 17,969
Nervous System 65 | 18,561
Respiratory system 65 | 17,484
Skin and soft tissues 65 | 18,115
Urinary Tract 65 | 18,444

Target Family

Kinase 22 | 634
Enzyme 18 | 4,146
Ion Channel 11 | 341
Non-IDG 9 | 11,971
Epigenetic 2 | 242
GPCR 2 | 406
Transcription Factor 1 | 1,400

KEGG Pathway

Long-term potentiation 65 | 65
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.76384 47.5 542
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.58202 42.2 123
Dual specificity mitogen-activated protein kinase kinase 2 MAP2K2 Tclin Kinase -1.78634 57.0 688
Ras-related protein Rap-1A RAP1A Tchem Enzyme -2.40521 288.3 256
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA Tchem Enzyme -2.95943 932.4 290
Ribosomal protein S6 kinase alpha-3 RPS6KA3 Tchem Kinase -2.46968 311.2 390
Ras-related protein Rap-1b RAP1B Tbio Enzyme -2.59731 397.5 89
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.60410 3186.8 1232
Adenylate cyclase type 8 ADCY8 Tchem Enzyme -2.01455 108.3 130