Development Level

Tbio 26 | 11,445
Tchem 20 | 1,598
Tclin 14 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
increased startle reflex 5 | 112
abnormal bone structure 4 | 187
increased heart weight 4 | 62
abnormal gait 3 | 69
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
decreased body weight 2 | 161
decreased hemoglobin content 2 | 68
decreased total body fat amoun... 2 | 207
increased neutrophil cell numb... 2 | 46
increased spleen weight 2 | 10
male infertility 2 | 123
short tibia 2 | 97
abnormal duodenum morphology 1 | 4
abnormal embryo size 1 | 220
abnormal gallbladder morpholog... 1 | 1
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal maxilla morphology 1 | 17
abnormal spleen morphology 1 | 55
abnormal vocalization 1 | 21
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged gallbladder 1 | 2
enlarged heart 1 | 210
enlarged spleen 1 | 41
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased respiratory quotient 1 | 2
prenatal lethality 1 | 28
small epididymis 1 | 3
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
vertebral fusion 1 | 23

Disease

Carcinoma 53 | 11,493
glioblastoma 41 | 5,792
ovarian cancer 40 | 8,520
medulloblastoma, large-cell 39 | 6,241
atypical teratoid / rhabdoid tumor 35 | 5,112
psoriasis 33 | 6,694
Kidney cancer 32 | 2,613
ependymoma 32 | 4,679
osteosarcoma 29 | 7,950
lung cancer 27 | 4,740
adult high grade glioma 26 | 3,801
Breast cancer 22 | 3,578
Cancer 22 | 2,499
astrocytic glioma 21 | 2,597
group 3 medulloblastoma 21 | 4,104
lung carcinoma 21 | 2,843
oligodendroglioma 21 | 2,850
primitive neuroectodermal tumor 21 | 3,035
Pick disease 20 | 1,894
Astrocytoma, Pilocytic 18 | 3,081
Intellectual disability 18 | 1,016
Epilepsy 17 | 792
Schizophrenia 17 | 1,160
lung adenocarcinoma 17 | 2,716
subependymal giant cell astrocytoma 16 | 2,287
Dull intelligence 15 | 645
Low intelligence 15 | 645
Melanoma 15 | 711
Mental Retardation 15 | 645
Mental deficiency 15 | 645
Poor school performance 15 | 645
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
pancreatic cancer 15 | 2,398
Liver cancer 14 | 604
colon cancer 14 | 1,478
Autosomal recessive predisposition 13 | 1,442
Short stature 13 | 531
group 4 medulloblastoma 13 | 1,855
pituitary cancer 13 | 1,972
Cognitive delay 12 | 608
Depressive disorder 12 | 409
Global developmental delay 12 | 608
Mental and motor retardation 12 | 608
Muscle hypotonia 12 | 571
interstitial cystitis 12 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Bipolar Disorder 11 | 666
Obesity 11 | 678
Substance Withdrawal Syndrome 11 | 55
malignant mesothelioma 11 | 3,232
tuberculosis 11 | 2,010
ulcerative colitis 11 | 1,819
Blepharoptosis 10 | 231
Seizures 10 | 596
pediatric high grade glioma 10 | 1,064
Adenoma 9 | 167
Breast Neoplasms 9 | 445
Mammary Neoplasms 9 | 425
Multiple myeloma 9 | 1,332
Skin cancer 9 | 469
astrocytoma 9 | 1,146
invasive ductal carcinoma 9 | 2,951
juvenile dermatomyositis 9 | 1,187
non-small cell lung cancer 9 | 2,890
Alzheimer's disease 8 | 658
Byzanthine arch palate 8 | 194
Downward slant of palpebral fissure 8 | 158
Dysarthria 8 | 192
Major Depressive Disorder 8 | 301
Mental Depression 8 | 333
Neurodegenerative disease 8 | 414
Nystagmus 8 | 317
Orbital separation excessive 8 | 244
Pectus excavatum 8 | 100
Strabismus 8 | 270
Thyroid cancer 8 | 36
breast carcinoma 8 | 1,638
diabetes mellitus 8 | 1,728
Acquired scoliosis 7 | 281
Chubby cheeks 7 | 50
Concave bridge of nose 7 | 195
Curvature of spine 7 | 282
Delayed bone age 7 | 136
Depressed nasal bridge 7 | 195
Depressed nasal root/bridge 7 | 195
Endometrial cancer 7 | 311
Feeding difficulties in infancy 7 | 175
Full cheeks 7 | 50
Hyperplasia of cheeks 7 | 50
Hypertrophy of cheeks 7 | 50
Hypoplastic mandible condyle 7 | 275
Kidney disease 7 | 430
Low set ears 7 | 181
Mandibular hypoplasia 7 | 275
Puffy cheeks 7 | 50
Short neck 7 | 140
adrenocortical carcinoma 7 | 1,428
cystic fibrosis 7 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962

Tissue

Endocrine System 59 | 18,159
Female tissues 59 | 17,400
Digestive Tract 58 | 17,369
Nervous System 57 | 16,725
Skin and soft tissues 57 | 17,230
Male tissues 56 | 17,142
Respiratory system 55 | 16,393
Blood and immune system 54 | 16,909
Urinary Tract 54 | 16,678
Liver and Pancreas 52 | 16,750
Cardiovascular System 50 | 15,192

Target Family

Enzyme 22 | 4,145
Non-IDG 15 | 12,091
Kinase 14 | 634
Ion Channel 9 | 344
GPCR 2 | 408

KEGG Pathway

Long-term depression 62 | 62
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Cytosolic phospholipase A2 gamma PLA2G4C Tchem Enzyme -1.27690 20.9 63
GTPase KRas KRAS Tchem Enzyme -3.80300 6069.9 574
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492
GTPase NRas NRAS Tchem Enzyme -3.01534 959.1 328
Guanine nucleotide-binding protein G(q) subunit alpha GNAQ Tbio Non-IDG -2.73429 514.5 206
Glutamate receptor ionotropic, delta-2 GRID2 Tbio Ion Channel -2.05105 116.1 74
Cytosolic phospholipase A2 delta PLA2G4D Tbio Enzyme -0.54284 3.41 45