Development Level

Tbio 70 | 11,445
Tchem 26 | 1,598
Tclin 10 | 613
Tdark 6 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
preweaning lethality, complete... 4 | 979
abnormal retina morphology 3 | 71
decreased circulating triglyce... 3 | 79
embryonic lethality prior to t... 3 | 278
abnormal bone mineralization 2 | 38
decreased body weight 2 | 161
decreased circulating amylase ... 2 | 28
decreased circulating creatini... 2 | 39
decreased circulating free fat... 2 | 31
decreased circulating insulin ... 2 | 76
decreased hematocrit 2 | 46
embryonic lethality prior to o... 2 | 239
increased lean body mass 2 | 172
increased spleen weight 2 | 10
increased total body fat amoun... 2 | 134
short tibia 2 | 97
abnormal cranium morphology 1 | 36
abnormal digit morphology 1 | 10
abnormal head morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
cataract 1 | 92
decreased IgG3 level 1 | 1
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased mean corpuscular vol... 1 | 79
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
enlarged uterus 1 | 11
hydrometra 1 | 53
impaired righting response 1 | 26
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased erythrocyte cell num... 1 | 39
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
male infertility 1 | 123
mammalian phenotype 1 | 17
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
shortened PR interval 1 | 6
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
stereotypic behavior 1 | 3
thin ventricular wall 1 | 24
trunk curl 1 | 16

Disease

Carcinoma 74 | 11,493
osteosarcoma 64 | 7,950
Cancer 63 | 2,499
ovarian cancer 62 | 8,520
glioblastoma 60 | 5,792
atypical teratoid / rhabdoid tumor 48 | 5,112
psoriasis 47 | 6,694
medulloblastoma, large-cell 45 | 6,241
lung cancer 43 | 4,740
invasive ductal carcinoma 39 | 2,951
ependymoma 36 | 4,679
interstitial cystitis 36 | 2,312
adult high grade glioma 34 | 3,801
lung carcinoma 34 | 2,843
pancreatic cancer 34 | 2,398
Breast cancer 31 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
non-small cell lung cancer 30 | 2,890
Astrocytoma, Pilocytic 29 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
lung adenocarcinoma 29 | 2,716
intraductal papillary-mucinous adenoma (IPMA) 28 | 2,955
subependymal giant cell astrocytoma 28 | 2,287
ulcerative colitis 27 | 1,819
malignant mesothelioma 26 | 3,232
oligodendroglioma 26 | 2,850
primitive neuroectodermal tumor 26 | 3,035
group 3 medulloblastoma 25 | 4,104
Kidney cancer 23 | 2,613
diabetes mellitus 23 | 1,728
cystic fibrosis 22 | 1,696
ductal carcinoma in situ 22 | 1,745
breast carcinoma 21 | 1,638
Schizophrenia 20 | 1,160
Liver Cirrhosis, Experimental 18 | 769
primary pancreatic ductal adenocarcinoma 18 | 1,109
Duchenne muscular dystrophy 17 | 601
astrocytoma 17 | 1,146
cutaneous lupus erythematosus 17 | 1,057
tuberculosis 17 | 2,010
Multiple Sclerosis 16 | 540
Rheumatoid arthritis 16 | 1,191
juvenile dermatomyositis 16 | 1,187
primary Sjogren syndrome 16 | 735
colon cancer 15 | 1,478
pituitary cancer 15 | 1,972
Kidney disease 14 | 430
Waldenstrons macroglobulinemia 14 | 765
astrocytic glioma 14 | 2,597
group 4 medulloblastoma 14 | 1,855
Autosomal recessive predisposition 13 | 1,442
dermatomyositis 13 | 966
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Down syndrome 12 | 499
adrenocortical carcinoma 12 | 1,428
gastric carcinoma 12 | 807
periodontitis 12 | 293
Arthritis 11 | 290
Breast Neoplasms 11 | 445
Hypertension 11 | 396
Mammary Neoplasms 11 | 425
Pick disease 11 | 1,894
Prostatic Neoplasms 11 | 495
pediatric high grade glioma 11 | 1,064
spina bifida 11 | 1,074
Asthma 10 | 385
Atopic dermatitis 10 | 952
Multiple myeloma 10 | 1,332
Neoplasm Invasiveness 10 | 161
Neoplasm Metastasis 10 | 168
Vascular disease 10 | 319
medulloblastoma 10 | 720
mucosa-associated lymphoid tissue lymphoma 10 | 484
Atherosclerosis 9 | 291
Carcinoma, Hepatocellular 9 | 228
Cell Transformation, Neoplastic 9 | 97
Coronary artery disease 9 | 268
Inflammatory bowel disease 9 | 151
Liver carcinoma 9 | 240
Mammary Neoplasms, Experimental 9 | 154
acute quadriplegic myopathy 9 | 1,158
esophageal adenocarcinoma 9 | 737
nasopharyngeal carcinoma 9 | 1,058
Becker muscular dystrophy 8 | 191
Cerebrovascular disease 8 | 238
Endometriosis 8 | 540
Heart disease 8 | 306
Hypertensive disease 8 | 292
Neoplastic Cell Transformation 8 | 89
Splenomegaly 8 | 190
active Crohn's disease 8 | 922
active ulcerative colitis 8 | 764
acute myeloid leukemia 8 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 8 | 510
head and neck cancer and chronic obstructive pulmonary disease 8 | 239
pancreatic carcinoma 8 | 562
posterior fossa group A ependymoma 8 | 468
urothelial carcinoma 8 | 318
Crohn's disease 7 | 321
aldosterone-producing adenoma 7 | 665

Tissue

Digestive Tract 109 | 17,369
Endocrine System 108 | 18,159
Female tissues 108 | 17,400
Skin and soft tissues 107 | 17,230
Urinary Tract 106 | 16,678
Liver and Pancreas 105 | 16,750
Male tissues 105 | 17,142
Blood and immune system 104 | 16,909
Nervous System 102 | 16,725
Respiratory system 100 | 16,393
Cardiovascular System 95 | 15,192

Target Family

Non-IDG 77 | 12,091
Kinase 17 | 634
Enzyme 16 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344

KEGG Pathway

Leukocyte transendothelial mig... 112 | 112
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras association domain-containing protein 5 RASSF5 Tbio Non-IDG -1.81149 71.3 155
Junctional adhesion molecule A F11R Tbio Non-IDG -2.56739 380.0 394
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Claudin-16 CLDN16 Tbio Non-IDG -1.98248 102.4 138
Myosin regulatory light chain 2, atrial isoform MYL7 Tbio Non-IDG -0.85198 5.20 169
Tyrosine-protein kinase TXK TXK Tchem Kinase -2.28365 191.1 194
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Claudin-1 CLDN1 Tbio Non-IDG -2.07626 126.7 593
Ras-related protein Rap-1b RAP1B Tbio Enzyme -2.38904 417.6 114
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461