Development Level

Tbio 100 | 11,445
Tclin 34 | 613
Tchem 25 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

enlarged heart 6 | 210
preweaning lethality, complete... 6 | 979
abnormal seminal vesicle morph... 5 | 114
abnormal heart morphology 4 | 162
increased mean corpuscular hem... 4 | 96
increased neutrophil cell numb... 4 | 46
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
decreased circulating creatini... 3 | 39
decreased lymphocyte cell numb... 3 | 83
decreased vertical activity 3 | 208
increased hemoglobin content 3 | 45
increased monocyte cell number 3 | 63
abnormal epididymis morphology 2 | 42
abnormal gait 2 | 69
abnormal lung morphology 2 | 26
abnormal spleen morphology 2 | 55
decreased blood urea nitrogen ... 2 | 51
decreased circulating LDL chol... 2 | 38
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased heart weight 2 | 27
decreased lean body mass 2 | 135
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
enlarged epididymis 2 | 31
enlarged lymph nodes 2 | 37
female infertility 2 | 60
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
impaired righting response 2 | 26
improved glucose tolerance 2 | 79
increased circulating LDL chol... 2 | 13
increased circulating alkaline... 2 | 122
increased circulating choleste... 2 | 66
increased hematocrit 2 | 46
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
limb grasping 2 | 41
male infertility 2 | 123
small seminal vesicle 2 | 10
thrombocytopenia 2 | 56
abnormal bone mineralization 1 | 38
abnormal brain morphology 1 | 13
abnormal eye morphology 1 | 68
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
cataract 1 | 92
corneal opacity 1 | 32
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
hydroencephaly 1 | 14
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytosis 1 | 27
tremors 1 | 39
trunk curl 1 | 16
vertebral fusion 1 | 23

Disease

Carcinoma 103 | 11,493
Cancer 89 | 2,499
psoriasis 83 | 6,694
ovarian cancer 80 | 8,520
osteosarcoma 76 | 7,950
lung cancer 70 | 4,740
glioblastoma 61 | 5,792
medulloblastoma, large-cell 57 | 6,241
malignant mesothelioma 56 | 3,232
Breast cancer 49 | 3,578
Schizophrenia 38 | 1,160
atypical teratoid / rhabdoid tumor 38 | 5,112
Rheumatoid arthritis 36 | 1,191
invasive ductal carcinoma 36 | 2,951
tuberculosis 35 | 2,010
non-small cell lung cancer 34 | 2,890
ulcerative colitis 34 | 1,819
adult high grade glioma 33 | 3,801
lung adenocarcinoma 33 | 2,716
Astrocytoma, Pilocytic 32 | 3,081
ependymoma 32 | 4,679
interstitial cystitis 32 | 2,312
lung carcinoma 31 | 2,843
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
pituitary cancer 29 | 1,972
Asthma 28 | 385
diabetes mellitus 28 | 1,728
group 3 medulloblastoma 27 | 4,104
Multiple Sclerosis 26 | 540
pancreatic cancer 26 | 2,398
Anemia 25 | 365
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
subependymal giant cell astrocytoma 25 | 2,287
Atopic dermatitis 24 | 952
Hypersensitivity reaction type II disease 24 | 253
Inflammatory bowel disease 24 | 151
Kidney cancer 24 | 2,613
cutaneous lupus erythematosus 24 | 1,057
cystic fibrosis 24 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
Autosomal recessive predisposition 23 | 1,442
Breast Neoplasms 23 | 445
Liver Cirrhosis, Experimental 23 | 769
Mammary Neoplasms 23 | 425
breast carcinoma 23 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,962
Arthritis 22 | 290
ductal carcinoma in situ 22 | 1,745
oligodendroglioma 22 | 2,850
Multiple myeloma 21 | 1,332
Prostatic Neoplasms 21 | 495
Hepatitis C 20 | 94
Major Depressive Disorder 20 | 301
Melanoma 20 | 711
astrocytic glioma 20 | 2,597
Autistic Disorder 18 | 364
group 4 medulloblastoma 18 | 1,855
Fever 17 | 138
Lung Neoplasms 17 | 232
Thrombocytopenia 17 | 197
colon cancer 17 | 1,478
Hepatitis B 16 | 108
Hypereosinophilic syndrome 16 | 71
Immune system cancer 16 | 140
Obesity 16 | 678
Pneumonia 16 | 174
Seizures 16 | 596
Unipolar Depression 16 | 250
primary Sjogren syndrome 16 | 735
Crohn's disease 15 | 321
Depressive disorder 15 | 409
Diarrhea 15 | 253
Liver carcinoma 15 | 240
Lymphoid leukemia 15 | 160
juvenile dermatomyositis 15 | 1,187
Adenoma 14 | 167
Allergic hypersensitivity disease 14 | 126
Dermatitis 14 | 157
Epilepsy 14 | 792
Fatigue 14 | 182
Heart disease 14 | 306
Hepatomegaly 14 | 285
Influenza 14 | 142
Kidney disease 14 | 430
Allergic rhinitis 13 | 94
Arthritis, Rheumatoid 13 | 174
Carcinoma, Hepatocellular 13 | 228
Hepatitis 13 | 67
Hypoplastic mandible condyle 13 | 275
Mandibular hypoplasia 13 | 275
Micrognathism 13 | 275
Renal Cell Carcinoma 13 | 214
Short stature 13 | 531
Stomach Neoplasms 13 | 300
Vascular disease 13 | 319
nasopharyngeal carcinoma 13 | 1,058
sarcoidosis 13 | 370
Spontaneous abortion 12 | 113
adrenocortical carcinoma 12 | 1,428
primitive neuroectodermal tumor 12 | 3,035

Tissue

Blood and immune system 145 | 16,909
Endocrine System 144 | 18,159
Digestive Tract 142 | 17,369
Skin and soft tissues 142 | 17,230
Male tissues 139 | 17,142
Female tissues 138 | 17,400
Liver and Pancreas 137 | 16,750
Urinary Tract 137 | 16,678
Respiratory system 135 | 16,393
Nervous System 125 | 16,725
Cardiovascular System 120 | 15,192

Target Family

Non-IDG 121 | 12,091
Kinase 17 | 634
Transcription Factor 13 | 1,400
Enzyme 8 | 4,145
Epigenetic 2 | 242

KEGG Pathway

Jak-STAT signaling pathway 161 | 161
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombopoietin THPO Tbio Non-IDG -3.23551 1632.3 440
Suppressor of cytokine signaling 4 SOCS4 Tbio Non-IDG -1.22763 14.8 224
Four and a half LIM domains protein 1 FHL1 Tbio Non-IDG -2.46134 291.4 312
Leukemia inhibitory factor receptor LIFR Tbio Non-IDG -2.35146 221.3 249
Cytokine receptor-like factor 2 CRLF2 Tbio Non-IDG -1.91113 78.7 393
Interleukin-19 IL19 Tbio Non-IDG -1.97214 102.3 249
Interferon alpha-1/13 IFNA13 Tbio Non-IDG -3.87160 7663.4 500
Interferon alpha-17 IFNA17 Tbio Non-IDG -2.39299 231.1 56
Chorionic somatomammotropin hormone 2 CSH2 Tbio Non-IDG -2.95755 830.6 89
GTPase HRas HRAS Tchem Enzyme -4.01300 9975.8 492