Development Level

Tbio 35 | 11,178
Tchem 34 | 1,885
Tclin 18 | 612
Tdark 1 | 6,569

Collection

Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal behavior 6 | 298
increased startle reflex 6 | 112
preweaning lethality, complete... 5 | 979
abnormal bone structure 4 | 187
increased heart weight 4 | 62
impaired glucose tolerance 3 | 75
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal gallbladder morpholog... 1 | 1
abnormal hindbrain development 1 | 16
abnormal locomotor behavior 1 | 24
abnormal neural tube closure 1 | 46
abnormal placenta vasculature 1 | 2
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
edema 1 | 59
enlarged gallbladder 1 | 2
enlarged heart 1 | 210
hemorrhage 1 | 23
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
male infertility 1 | 123
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
respiratory system phenotype 1 | 2
scaly skin 1 | 4
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thick skin 1 | 4
vertebral fusion 1 | 23

Disease

Carcinoma 64 | 11,192
atypical teratoid / rhabdoid tumor 43 | 4,971
glioblastoma 42 | 5,635
medulloblastoma, large-cell 42 | 6,086
adult high grade glioma 38 | 3,701
ependymoma 38 | 4,559
psoriasis 37 | 6,514
ovarian cancer 34 | 8,297
primitive neuroectodermal tumor 33 | 2,957
group 3 medulloblastoma 32 | 4,002
osteosarcoma 32 | 7,766
Astrocytoma, Pilocytic 30 | 3,006
Kidney cancer 27 | 2,548
oligodendroglioma 27 | 2,768
lung cancer 26 | 4,607
lung carcinoma 26 | 2,755
astrocytic glioma 24 | 2,530
Breast cancer 23 | 3,469
Bipolar Disorder 22 | 646
diabetes mellitus 21 | 1,683
subependymal giant cell astrocytoma 21 | 2,230
Obesity 20 | 655
intraductal papillary-mucinous carcinoma (IPMC) 20 | 2,902
Epilepsy 19 | 775
Schizophrenia 19 | 1,136
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,872
lung adenocarcinoma 19 | 2,627
pancreatic cancer 19 | 2,322
Pick disease 18 | 1,856
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,204
malignant mesothelioma 18 | 3,135
pituitary cancer 17 | 1,915
Depressive disorder 16 | 401
interstitial cystitis 16 | 2,237
colon cancer 15 | 1,428
Cancer 14 | 2,388
Liver cancer 14 | 589
Hyperglycemia 13 | 134
Mental Depression 13 | 325
group 4 medulloblastoma 13 | 1,806
invasive ductal carcinoma 13 | 2,867
Autosomal recessive predisposition 12 | 1,407
Diabetes Mellitus, Type 2 12 | 136
Hypertension 12 | 372
Hypertensive disease 12 | 278
Seizures 12 | 584
Unipolar Depression 12 | 244
ulcerative colitis 12 | 1,765
Atrial Fibrillation 11 | 120
Cognitive delay 11 | 596
Diabetes Mellitus, Non-Insulin-Dependent 11 | 140
Global developmental delay 11 | 596
Hypoglycemia 11 | 146
Major Depressive Disorder 11 | 293
Mental and motor retardation 11 | 596
non-small cell lung cancer 11 | 2,799
Melanoma 10 | 689
Skin cancer 10 | 451
astrocytoma 10 | 1,113
Adenoma 9 | 159
Chronic heart failure 9 | 44
Congestive heart failure 9 | 109
Intellectual disability 9 | 998
Muscle Weakness 9 | 168
cystic fibrosis 9 | 1,629
Congenital Heart Defects 8 | 57
Hyperinsulinism 8 | 128
Parkinson's disease 8 | 378
Poisoning by digitalis glycoside 8 | 8
Tonic - clonic seizures 8 | 43
Type 2 diabetes mellitus 8 | 268
Acquired metabolic disease 7 | 329
Axial hypotonia 7 | 46
Cushing's syndrome 7 | 47
Dull intelligence 7 | 634
Failure to gain weight 7 | 359
Hypertensive disorder 7 | 56
Insulinoma 7 | 24
Low intelligence 7 | 634
Mental Retardation 7 | 634
Mental deficiency 7 | 634
Mood Disorders 7 | 181
Pediatric failure to thrive 7 | 359
Polycystic ovary syndrome 7 | 348
Poor school performance 7 | 634
Substance Withdrawal Syndrome 7 | 53
Vascular disease 7 | 294
Weight decreased 7 | 101
breast carcinoma 7 | 1,589
ductal carcinoma in situ 7 | 1,686
Acromegaly 6 | 48
Alzheimer's disease 6 | 640
Endometrial cancer 6 | 301
Heart disease 6 | 288
Hyperreflexia 6 | 208
Kidney disease 6 | 411
Long philtrum 6 | 137
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,911
substance-related disorder 6 | 156
tuberculosis 6 | 1,963

Tissue

Endocrine System 84 | 18,159
Digestive Tract 83 | 17,369
Liver and Pancreas 81 | 16,750
Nervous System 81 | 16,725
Skin and soft tissues 80 | 17,230
Blood and immune system 79 | 16,909
Female tissues 78 | 17,400
Urinary Tract 77 | 16,678
Male tissues 76 | 17,142
Respiratory system 76 | 16,393
Cardiovascular System 73 | 15,192

Target Family

Ion Channel 18 | 344
Enzyme 16 | 4,145
Non-IDG 15 | 12,091
Kinase 11 | 634
Transcription Factor 11 | 1,400
Transporter 11 | 473
GPCR 6 | 408

KEGG Pathway

Insulin secretion 88 | 88
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily M member 4 TRPM4 Tchem Ion Channel -2.19653 160.9 186
Adenylate cyclase type 3 ADCY3 Tbio Enzyme -2.31593 204.4 82
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 PLCB4 Tbio Enzyme -1.77110 57.7 19
Glucose-dependent insulinotropic receptor GPR119 Tchem GPCR -2.06190 120.0 180
Cyclic AMP-responsive element-binding protein 3-like protein 4 CREB3L4 Tbio Transcription Factor -1.64875 47.6 188
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435
Glucagon-like peptide 1 receptor GLP1R Tclin GPCR -2.92059 820.5 306
Calcium-activated potassium channel subunit beta-3 KCNMB3 Tbio Ion Channel -0.76009 6.19 184
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Small conductance calcium-activated potassium channel protein 3 KCNN3 Tchem Ion Channel -2.41492 272.1 119