Development Level

Tbio 41 | 11,445
Tchem 28 | 1,598
Tclin 18 | 613
Tdark 1 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99
Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal behavior 6 | 298
increased startle reflex 6 | 112
preweaning lethality, complete... 5 | 979
abnormal bone structure 4 | 187
increased heart weight 4 | 62
impaired glucose tolerance 3 | 75
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal gait 1 | 69
abnormal gallbladder morpholog... 1 | 1
abnormal hindbrain development 1 | 16
abnormal locomotor behavior 1 | 24
abnormal neural tube closure 1 | 46
abnormal placenta vasculature 1 | 2
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 36
cyanosis 1 | 7
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased prepulse inhibition 1 | 82
edema 1 | 59
enlarged gallbladder 1 | 2
enlarged heart 1 | 210
hemorrhage 1 | 23
hydrometra 1 | 53
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased or absent threshold ... 1 | 101
male infertility 1 | 123
prenatal lethality 1 | 28
prolonged PR interval 1 | 15
respiratory system phenotype 1 | 2
scaly skin 1 | 4
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thick skin 1 | 4
vertebral fusion 1 | 23

Disease

Carcinoma 66 | 11,493
atypical teratoid / rhabdoid tumor 44 | 5,112
medulloblastoma, large-cell 44 | 6,241
glioblastoma 43 | 5,792
adult high grade glioma 39 | 3,801
ependymoma 38 | 4,679
psoriasis 38 | 6,694
ovarian cancer 36 | 8,520
osteosarcoma 34 | 7,950
group 3 medulloblastoma 33 | 4,104
primitive neuroectodermal tumor 33 | 3,035
Astrocytoma, Pilocytic 30 | 3,081
Kidney cancer 27 | 2,613
lung cancer 27 | 4,740
lung carcinoma 27 | 2,843
oligodendroglioma 27 | 2,850
astrocytic glioma 25 | 2,597
Breast cancer 24 | 3,578
Bipolar Disorder 22 | 666
diabetes mellitus 21 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
subependymal giant cell astrocytoma 21 | 2,287
Obesity 20 | 678
pancreatic cancer 20 | 2,398
Epilepsy 19 | 792
Pick disease 19 | 1,894
Schizophrenia 19 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
lung adenocarcinoma 19 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
malignant mesothelioma 18 | 3,232
pituitary cancer 17 | 1,972
Depressive disorder 16 | 409
interstitial cystitis 16 | 2,312
Cancer 15 | 2,499
colon cancer 15 | 1,478
Liver cancer 14 | 604
group 4 medulloblastoma 14 | 1,855
invasive ductal carcinoma 14 | 2,951
Hyperglycemia 13 | 137
Mental Depression 13 | 333
Autosomal recessive predisposition 12 | 1,442
Diabetes Mellitus, Type 2 12 | 142
Hypertension 12 | 396
Hypertensive disease 12 | 292
Seizures 12 | 596
Unipolar Depression 12 | 250
non-small cell lung cancer 12 | 2,890
ulcerative colitis 12 | 1,819
Atrial Fibrillation 11 | 124
Cognitive delay 11 | 608
Diabetes Mellitus, Non-Insulin-Dependent 11 | 145
Global developmental delay 11 | 608
Hypoglycemia 11 | 152
Major Depressive Disorder 11 | 301
Mental and motor retardation 11 | 608
Melanoma 10 | 711
Skin cancer 10 | 469
astrocytoma 10 | 1,146
Adenoma 9 | 167
Chronic heart failure 9 | 46
Congestive heart failure 9 | 113
Intellectual disability 9 | 1,016
Muscle Weakness 9 | 170
cystic fibrosis 9 | 1,696
Congenital Heart Defects 8 | 58
Hyperinsulinism 8 | 133
Parkinson's disease 8 | 392
Poisoning by digitalis glycoside 8 | 8
Tonic - clonic seizures 8 | 44
Type 2 diabetes mellitus 8 | 272
breast carcinoma 8 | 1,638
ductal carcinoma in situ 8 | 1,745
Acquired metabolic disease 7 | 336
Axial hypotonia 7 | 46
Cushing's syndrome 7 | 48
Dull intelligence 7 | 645
Failure to gain weight 7 | 365
Insulinoma 7 | 24
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Mood Disorders 7 | 184
Pediatric failure to thrive 7 | 365
Polycystic ovary syndrome 7 | 360
Poor school performance 7 | 645
Substance Withdrawal Syndrome 7 | 55
Vascular disease 7 | 319
Weight decreased 7 | 103
tuberculosis 7 | 2,010
Acromegaly 6 | 51
Alzheimer's disease 6 | 658
Endometrial cancer 6 | 311
Heart disease 6 | 306
Hypothyroidism 6 | 122
Kidney disease 6 | 430
Long philtrum 6 | 137
Rheumatoid arthritis 6 | 1,191
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
substance-related disorder 6 | 162

Tissue

Endocrine System 84 | 18,159
Digestive Tract 83 | 17,369
Liver and Pancreas 81 | 16,750
Nervous System 81 | 16,725
Skin and soft tissues 80 | 17,230
Blood and immune system 79 | 16,909
Female tissues 78 | 17,400
Urinary Tract 77 | 16,678
Male tissues 76 | 17,142
Respiratory system 76 | 16,393
Cardiovascular System 73 | 15,192

Target Family

Ion Channel 18 | 344
Enzyme 16 | 4,145
Non-IDG 15 | 12,091
Kinase 11 | 634
Transcription Factor 11 | 1,400
Transporter 11 | 473
GPCR 6 | 408

KEGG Pathway

Insulin secretion 88 | 88
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Calcium-activated potassium channel subunit beta-2 KCNMB2 Tbio Ion Channel 1.28 0.09 191
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Sodium/potassium-transporting ATPase subunit alpha-4 ATP1A4 Tclin Transporter -1.73566 51.3 5
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Calcium-activated potassium channel subunit beta-4 KCNMB4 Tbio Ion Channel -0.98233 8.05 132
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344
Sodium/potassium-transporting ATPase subunit gamma FXYD2 Tclin Enzyme -1.58017 39.0 64
Potassium channel subfamily U member 1 KCNU1 Tbio Ion Channel -1.65772 43.3 45