Development Level

Tbio 35 | 10,625
Tchem 34 | 1,890
Tclin 18 | 602
Tdark 1 | 7,003

Collection

Eligible Ion Channel Proteins 4 | 117
Eligible Kinase Proteins 2 | 134

IMPC Term

abnormal bone mineralization 5 | 55
abnormal bone structure 4 | 131
increased heart weight 4 | 37
preweaning lethality, complete... 4 | 633
abnormal behavior 3 | 226
preweaning lethality, incomple... 3 | 260
abnormal embryo size 2 | 112
embryonic lethality prior to t... 2 | 187
impaired glucose tolerance 2 | 52
increased circulating alkaline... 2 | 119
abnormal facial morphology 1 | 9
abnormal forebrain development 1 | 18
abnormal hindbrain development 1 | 24
abnormal neural tube closure 1 | 37
abnormal placenta vasculature 1 | 2
abnormal seminal vesicle morph... 1 | 47
abnormal spleen morphology 1 | 36
abnormal vocalization 1 | 21
cardiovascular system phenotyp... 1 | 35
cyanosis 1 | 6
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 24
decreased circulating chloride... 1 | 32
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased circulating total pr... 1 | 41
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased mean corpuscular vol... 1 | 50
decreased prepulse inhibition 1 | 52
edema 1 | 11
enlarged heart 1 | 111
enlarged spleen 1 | 26
hemorrhage 1 | 12
hyperactivity 1 | 108
hypoactivity 1 | 89
increased bone mineral content 1 | 92
increased circulating calcium ... 1 | 32
increased fasted circulating g... 1 | 68
increased or absent threshold ... 1 | 128
increased startle reflex 1 | 38
male infertility 1 | 62
prenatal lethality 1 | 16
respiratory system phenotype 1 | 2
vertebral fusion 1 | 23

Disease

medulloblastoma, large-cell 44 | 6,234
glioblastoma 40 | 5,572
psoriasis 38 | 6,685
atypical teratoid / rhabdoid tumor 37 | 4,369
osteosarcoma 34 | 7,933
ovarian cancer 33 | 8,484
primitive neuroectodermal tumor 33 | 3,031
pilocytic astrocytoma 30 | 3,086
lung carcinoma 27 | 2,844
oligodendroglioma 27 | 2,849
Carcinoma 26 | 2,147
pediatric high grade glioma 26 | 2,712
ependymoma 23 | 2,514
lung cancer 22 | 4,466
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,988
subependymal giant cell astrocytoma 21 | 2,287
Obesity 20 | 616
Pick disease 19 | 1,893
diabetes mellitus 19 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
lung adenocarcinoma 19 | 2,713
astrocytoma 18 | 1,493
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,289
astrocytic glioma 17 | 2,241
malignant mesothelioma 17 | 3,162
medulloblastoma 17 | 1,524
pancreatic cancer 17 | 2,300
pituitary cancer 17 | 1,972
adult high grade glioma 16 | 2,148
interstitial cystitis 16 | 2,299
Breast cancer 15 | 3,094
Cancer 15 | 2,346
colon cancer 15 | 1,475
invasive ductal carcinoma 14 | 2,950
group 3 medulloblastoma 13 | 2,254
sonic hedgehog group medulloblastoma 13 | 1,482
ulcerative colitis 13 | 2,087
Atrial Fibrillation 12 | 110
Diabetes Mellitus, Non-Insulin-Dependent 11 | 157
Hyperglycemia 11 | 120
Hypoglycemia 11 | 81
Schizophrenia 11 | 501
Epilepsy 10 | 346
Hypertensive disease 10 | 193
group 4 medulloblastoma 10 | 1,875
non-small cell lung cancer 10 | 2,798
Adenoma 9 | 165
Bipolar Disorder 9 | 266
Chronic heart failure 9 | 46
atypical teratoid/rhabdoid tumor 9 | 1,095
cystic fibrosis 9 | 1,665
posterior fossa group A ependymoma 9 | 1,511
Congestive heart failure 8 | 30
Hyperinsulinism 8 | 63
Parkinson's disease 8 | 364
Poisoning by digitalis glycoside 8 | 8
breast carcinoma 8 | 1,614
ductal carcinoma in situ 8 | 1,745
posterior fossa group B ependymoma 8 | 1,530
Acquired metabolic disease 7 | 267
Cushing's syndrome 7 | 47
Hypertensive disorder 7 | 58
Type 2 diabetes mellitus 7 | 189
Vascular disease 7 | 281
Acromegaly 6 | 40
Alzheimer's disease 6 | 644
Carney complex 6 | 23
Diabetes Mellitus, Experimental 6 | 106
Hyperthyroidism 6 | 50
Hypothyroidism 6 | 89
Insulinoma 6 | 20
Kidney cancer 6 | 118
Kidney disease 6 | 396
Metabolic syndrome X 6 | 155
Multiple Endocrine Neoplasia Type 1 6 | 30
Rheumatoid Arthritis 6 | 1,160
maturity-onset diabetes of the young 6 | 28
primary pancreatic ductal adenocarcinoma 6 | 1,271
tuberculosis and treatment for 3 months 6 | 327
Autistic Disorder 5 | 320
Beckwith-Wiedemann syndrome 5 | 46
DIABETES MELLITUS, PERMANENT NEONATAL 5 | 5
Fibrous dysplasia 5 | 15
Heart disease 5 | 279
Hyperinsulinemic hypoglycemia 5 | 17
Hypertension 5 | 287
McCune Albright syndrome 5 | 19
Pituitary adenoma 5 | 35
Pseudohypoparathyroidism 5 | 17
adrenocortical carcinoma 5 | 1,427
chronic rhinosinusitis 5 | 512
juvenile dermatomyositis 5 | 1,189
non-small cell lung carcinoma 5 | 413
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
primary Sjogren syndrome 5 | 789
Crohn's disease 4 | 304
Duchenne muscular dystrophy 4 | 602
Polycystic Ovary Syndrome 4 | 332
cutaneous lupus erythematosus 4 | 1,056
progressive supranuclear palsy 4 | 674

Tissue

Digestive Tract 87 | 18,473
Endocrine System 87 | 18,512
Female tissues 87 | 18,647
Nervous System 87 | 18,561
Blood and immune system 86 | 17,995
Liver and Pancreas 86 | 18,136
Urinary Tract 85 | 18,444
Cardiovascular System 84 | 17,958
Male tissues 84 | 17,969
Skin and soft tissues 84 | 18,115
Respiratory system 78 | 17,484

Target Family

Ion Channel 18 | 341
Enzyme 16 | 4,146
Non-IDG 15 | 11,971
Kinase 11 | 634
Transcription Factor 11 | 1,400
Transporter 11 | 473
GPCR 6 | 406

KEGG Pathway

Insulin secretion 88 | 88
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Insulin resistance 109 | 109
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pancreas/duodenum homeobox protein 1 PDX1 Tbio Transcription Factor -2.33707 243.8 508
Cyclic AMP-responsive element-binding protein 3 CREB3 Tbio Transcription Factor -1.61736 42.0 159
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.76384 47.5 542
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Adenylate cyclase type 1 ADCY1 Tchem Enzyme -1.58202 42.2 123
Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2 Tclin Transporter -2.04732 117.9 108
Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 Tchem Ion Channel -2.38460 284.0 184
Sodium/potassium-transporting ATPase subunit alpha-3 ATP1A3 Tclin Transporter -2.09703 131.9 103
Cyclic AMP-responsive element-binding protein 3-like protein 2 CREB3L2 Tbio Transcription Factor -2.46118 296.9 147
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.66594 47.2 113