Development Level

Tchem 58 | 1,890
Tbio 41 | 10,625
Tclin 8 | 602
Tdark 2 | 7,003

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

increased circulating alkaline... 4 | 119
decreased circulating LDL chol... 3 | 37
decreased lean body mass 3 | 195
increased hematocrit 3 | 36
increased mean corpuscular hem... 3 | 93
preweaning lethality, complete... 3 | 633
abnormal lens morphology 2 | 73
decreased body weight 2 | 174
decreased circulating amylase ... 2 | 24
decreased circulating choleste... 2 | 85
decreased circulating creatini... 2 | 31
decreased mean corpuscular hem... 2 | 19
decreased threshold for audito... 2 | 32
decreased total body fat amoun... 2 | 186
enlarged spleen 2 | 26
increased circulating LDL chol... 2 | 15
preweaning lethality, incomple... 2 | 260
abnormal bone mineralization 1 | 55
abnormal cornea morphology 1 | 24
abnormal glucose homeostasis 1 | 5
abnormal locomotor activation 1 | 26
abnormal respiratory quotient 1 | 9
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal rib morphology 1 | 28
abnormal skin condition 1 | 6
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 17
anophthalmia 1 | 20
cardiovascular system phenotyp... 1 | 35
decreased CD5-positive Ly6C-po... 1 | 4
decreased CD8-positive, alpha-... 1 | 26
decreased CD8-positive, naive ... 1 | 5
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased erythrocyte cell num... 1 | 43
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased mean corpuscular vol... 1 | 50
decreased spleen weight 1 | 13
decreased thermal nociceptive ... 1 | 4
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
hypoactivity 1 | 89
immune system phenotype 1 | 17
impaired glucose tolerance 1 | 52
increased bone mineral density 1 | 52
increased circulating alanine ... 1 | 11
increased circulating aspartat... 1 | 17
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating choleste... 1 | 53
increased circulating free fat... 1 | 17
increased circulating iron lev... 1 | 25
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20
increased effector memory T-he... 1 | 5
increased erythrocyte cell num... 1 | 26
increased glycosylated hemoglo... 1 | 1
increased heart rate 1 | 17
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased mean corpuscular vol... 1 | 91
increased mean platelet volume 1 | 19
increased memory-marker gamma-... 1 | 2
increased red blood cell distr... 1 | 21
increased spleen weight 1 | 3
increased thermal nociceptive ... 1 | 9
male infertility 1 | 62
short tibia 1 | 82
shortened RR interval 1 | 19
small testis 1 | 37
thrombocytosis 1 | 23

Disease

osteosarcoma 64 | 7,933
ovarian cancer 62 | 8,484
psoriasis 58 | 6,685
medulloblastoma, large-cell 50 | 6,234
Cancer 48 | 2,346
glioblastoma 47 | 5,572
diabetes mellitus 45 | 1,663
lung cancer 40 | 4,466
Obesity 39 | 616
atypical teratoid / rhabdoid tumor 33 | 4,369
invasive ductal carcinoma 32 | 2,950
Hyperglycemia 28 | 120
Breast cancer 27 | 3,094
subependymal giant cell astrocytoma 27 | 2,287
ependymoma 26 | 2,514
Metabolic syndrome X 25 | 155
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
lung adenocarcinoma 25 | 2,713
group 4 medulloblastoma 24 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
pilocytic astrocytoma 24 | 3,086
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,289
oligodendroglioma 23 | 2,849
astrocytoma 22 | 1,493
interstitial cystitis 22 | 2,299
malignant mesothelioma 22 | 3,162
non-small cell lung cancer 22 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,795
pituitary cancer 22 | 1,972
ulcerative colitis 22 | 2,087
primitive neuroectodermal tumor 21 | 3,031
tuberculosis 21 | 1,557
Carcinoma 20 | 2,147
Diabetes Mellitus, Non-Insulin-Dependent 20 | 157
adult high grade glioma 20 | 2,148
lung carcinoma 20 | 2,844
ductal carcinoma in situ 19 | 1,745
pediatric high grade glioma 19 | 2,712
Diabetes Mellitus, Experimental 17 | 106
colon cancer 17 | 1,475
Hyperinsulinism 16 | 63
Pick disease 16 | 1,893
adrenocortical carcinoma 16 | 1,427
breast carcinoma 16 | 1,614
cystic fibrosis 16 | 1,665
group 3 medulloblastoma 16 | 2,254
pancreatic cancer 16 | 2,300
Alzheimer's disease 15 | 644
Insulin Resistance 15 | 48
Liver carcinoma 15 | 217
Mammary Neoplasms 15 | 410
astrocytic glioma 15 | 2,241
Fatty liver disease 14 | 84
Vascular disease 14 | 281
Rheumatoid Arthritis 13 | 1,160
Schizophrenia 13 | 501
medulloblastoma 13 | 1,524
Kidney disease 12 | 396
Prostatic Neoplasms 12 | 471
Stomach Neoplasms 12 | 282
posterior fossa group A ependymoma 12 | 1,511
Parkinson's disease 11 | 364
Polycystic Ovary Syndrome 11 | 332
dermatomyositis 11 | 933
juvenile dermatomyositis 11 | 1,189
posterior fossa group B ependymoma 11 | 1,530
Atherosclerosis 10 | 275
Cardiomegaly 10 | 66
Glycogen storage disease 10 | 37
Heart disease 10 | 279
Hypertensive disease 10 | 193
Hypoglycemia 10 | 81
Lipid metabolism disorder 10 | 102
Reperfusion Injury 10 | 84
acute quadriplegic myopathy 10 | 1,157
Arthritis 9 | 248
Brain Ischemia 9 | 87
Heart failure 9 | 80
Multiple myeloma 9 | 1,327
Myocardial Ischemia 9 | 169
acute myeloid leukemia 9 | 780
primary Sjogren syndrome 9 | 789
spina bifida 9 | 1,064
Asthma 8 | 349
Coronary artery disease 8 | 240
Hypertension 8 | 287
Inflammatory bowel disease 8 | 142
Kidney Failure, Chronic 8 | 45
Liver disease 8 | 219
Renal Cell Carcinoma 8 | 199
Toxic encephalopathy 8 | 131
Waldenstrons macroglobulinemia 8 | 765
atypical teratoid/rhabdoid tumor 8 | 1,095
ovarian neoplasm 8 | 97
pancreatic carcinoma 8 | 567
cutaneous lupus erythematosus 7 | 1,056
fibroadenoma 7 | 557
nasopharyngeal carcinoma 7 | 1,056
nephrosclerosis 7 | 329
primary pancreatic ductal adenocarcinoma 7 | 1,271

Tissue

Blood and immune system 109 | 17,995
Cardiovascular System 109 | 17,958
Digestive Tract 109 | 18,473
Endocrine System 109 | 18,512
Female tissues 109 | 18,647
Liver and Pancreas 109 | 18,136
Nervous System 109 | 18,561
Skin and soft tissues 109 | 18,115
Urinary Tract 109 | 18,444
Male tissues 108 | 17,969
Respiratory system 107 | 17,484

Target Family

Enzyme 35 | 4,146
Kinase 34 | 634
Transcription Factor 15 | 1,400
Non-IDG 13 | 11,971
Transporter 9 | 473
Nuclear Receptor 3 | 48

KEGG Pathway

Insulin resistance 109 | 109
Metabolic pathways 1,254 | 1,254
Olfactory transduction 412 | 412
Pathways in cancer 402 | 402
HTLV-I infection 339 | 339
PI3K-Akt signaling pathway 338 | 338
Endocytosis 326 | 326
Epstein-Barr virus infection 279 | 279
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 262 | 262
Herpes simplex infection 262 | 262
MAPK signaling pathway 255 | 255
Viral carcinogenesis 253 | 253
Phagosome 231 | 231
Cell adhesion molecules (CAMs) 225 | 225
Ras signaling pathway 225 | 225
Rap1 signaling pathway 213 | 213
Regulation of actin cytoskelet... 213 | 213
Proteoglycans in cancer 202 | 202
cAMP signaling pathway 201 | 201
Focal adhesion 200 | 200
Natural killer cell mediated c... 199 | 199
Huntington's disease 194 | 194
Tuberculosis 187 | 187
Influenza A 184 | 184
Chemokine signaling pathway 182 | 182
Calcium signaling pathway 181 | 181
Axon guidance 176 | 176
Purine metabolism 171 | 171
Alzheimer's disease 169 | 169
Tight junction 169 | 169
NOD-like receptor signaling pa... 168 | 168
Protein processing in endoplas... 165 | 165
Transcriptional misregulation ... 165 | 165
cGMP-PKG signaling pathway 165 | 165
RNA transport 164 | 164
Oxytocin signaling pathway 158 | 158
Jak-STAT signaling pathway 157 | 157
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
mTOR signaling pathway 153 | 153
Non-alcoholic fatty liver dise... 151 | 151
Adrenergic signaling in cardio... 150 | 150
MicroRNAs in cancer 150 | 150
Breast cancer 146 | 146
Alcoholism 145 | 145
Hepatitis B 145 | 145
Phospholipase D signaling path... 145 | 145
Parkinson's disease 142 | 142
Wnt signaling pathway 142 | 142
Signaling pathways regulating ... 141 | 141
Apoptosis 140 | 140
Insulin signaling pathway 138 | 138
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Measles 135 | 135
Ribosome 134 | 134
Oxidative phosphorylation 133 | 133
FoxO signaling pathway 132 | 132
Hepatitis C 132 | 132
Spliceosome 132 | 132
Dopaminergic synapse 131 | 131
Osteoclast differentiation 131 | 131
Autoimmune thyroid disease 130 | 130
Toxoplasmosis 130 | 130
Cell cycle 125 | 125
Platelet activation 124 | 124
AMPK signaling pathway 123 | 123
Lysosome 123 | 123
Type I diabetes mellitus 122 | 122
Vascular smooth muscle contrac... 121 | 121
Graft-versus-host disease 120 | 120
Sphingolipid signaling pathway 120 | 120
Neurotrophin signaling pathway 119 | 119
Oocyte meiosis 119 | 119
Th17 cell differentiation 119 | 119
Thyroid hormone signaling path... 118 | 118
Allograft rejection 116 | 116
Glutamatergic synapse 116 | 116
Leukocyte transendothelial mig... 116 | 116
Carbon metabolism 114 | 114
Serotonergic synapse 114 | 114
Cholinergic synapse 110 | 110
TNF signaling pathway 110 | 110
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
Chagas disease (American trypa... 106 | 106
T cell receptor signaling path... 104 | 104
Th1 and Th2 cell differentiati... 104 | 104
Glucagon signaling pathway 103 | 103
HIF-1 signaling pathway 103 | 103
Toll-like receptor signaling p... 103 | 103
Melanogenesis 102 | 102
Pyrimidine metabolism 102 | 102
AGE-RAGE signaling pathway in ... 101 | 101
Endocrine resistance 101 | 101
Estrogen signaling pathway 101 | 101
Retrograde endocannabinoid sig... 101 | 101
Amoebiasis 100 | 100
Rheumatoid arthritis 100 | 100

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier family 2, facilitated glucose transporter member 4 SLC2A4 Tchem Transporter -3.30074 2066.8 474
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.48996 301.3 641
Cyclic AMP-responsive element-binding protein 3 CREB3 Tbio Transcription Factor -1.61736 42.0 159
Insulin INS Tbio Non-IDG -5.14691 141255.4 1549
Protein phosphatase 1 regulatory subunit 3C PPP1R3C Tbio Enzyme -2.41843 288.0 78
Peroxisome proliferator-activated receptor gamma coactivator 1-beta PPARGC1B Tbio Non-IDG -2.61803 420.9 51
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.30451 203.2 252
Glycogen synthase kinase-3 beta GSK3B Tclin Kinase -2.94349 567.7 767
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34160 1960.9 1181
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OGT Tchem Enzyme -2.92944 916.6 217