Development Level

Tbio 100 | 11,445
Tchem 55 | 1,598
Tclin 20 | 613
Tdark 7 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 5 | 979
embryonic lethality prior to t... 4 | 278
decreased body weight 3 | 161
decreased circulating creatini... 3 | 39
decreased mean corpuscular vol... 3 | 79
enlarged heart 3 | 210
increased neutrophil cell numb... 3 | 46
preweaning lethality, incomple... 3 | 499
abnormal gait 2 | 69
abnormal seminal vesicle morph... 2 | 114
decreased bone mineral content 2 | 151
decreased lymphocyte cell numb... 2 | 83
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
increased circulating alkaline... 2 | 122
increased eosinophil cell numb... 2 | 11
increased erythrocyte cell num... 2 | 39
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased lymphocyte cell numb... 2 | 32
pallor 2 | 34
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal glucose homeostasis 1 | 4
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal skin condition 1 | 6
abnormal vibrissa morphology 1 | 25
brachydactyly 1 | 19
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating insulin ... 1 | 76
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged lymph nodes 1 | 37
enlarged uterus 1 | 11
female infertility 1 | 60
impaired righting response 1 | 26
increased basophil cell number 1 | 7
increased circulating LDL chol... 1 | 13
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
pale yolk sac 1 | 25
prenatal lethality prior to he... 1 | 87
prolonged PR interval 1 | 15
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

Carcinoma 107 | 11,493
Cancer 91 | 2,499
ovarian cancer 91 | 8,520
psoriasis 80 | 6,694
glioblastoma 76 | 5,792
lung cancer 76 | 4,740
osteosarcoma 72 | 7,950
medulloblastoma, large-cell 59 | 6,241
atypical teratoid / rhabdoid tumor 52 | 5,112
Rheumatoid arthritis 51 | 1,191
tuberculosis 51 | 2,010
lung carcinoma 49 | 2,843
Multiple Sclerosis 48 | 540
adult high grade glioma 48 | 3,801
diabetes mellitus 48 | 1,728
malignant mesothelioma 46 | 3,232
Astrocytoma, Pilocytic 45 | 3,081
pancreatic cancer 45 | 2,398
ependymoma 44 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 44 | 3,291
invasive ductal carcinoma 41 | 2,951
Schizophrenia 40 | 1,160
cystic fibrosis 39 | 1,696
Breast cancer 38 | 3,578
juvenile dermatomyositis 38 | 1,187
subependymal giant cell astrocytoma 38 | 2,287
Arthritis 37 | 290
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,955
Hypersensitivity reaction type II disease 35 | 253
Influenza 35 | 142
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,989
interstitial cystitis 33 | 2,312
cutaneous lupus erythematosus 32 | 1,057
non-small cell lung cancer 31 | 2,890
Kidney cancer 30 | 2,613
Systemic lupus erythematosus 30 | 194
Asthma 29 | 385
lung adenocarcinoma 29 | 2,716
ulcerative colitis 28 | 1,819
Multiple myeloma 27 | 1,332
breast carcinoma 26 | 1,638
dermatomyositis 26 | 966
Inflammatory bowel disease 25 | 151
Vascular disease 25 | 319
sarcoidosis 25 | 370
Lung disease 24 | 142
oligodendroglioma 24 | 2,850
primary Sjogren syndrome 24 | 735
Brain Ischemia 23 | 110
Kidney disease 23 | 430
Prostatic Neoplasms 23 | 495
astrocytoma 23 | 1,146
group 4 medulloblastoma 23 | 1,855
Obesity 22 | 678
group 3 medulloblastoma 22 | 4,104
Bipolar Disorder 21 | 666
Liver disease 21 | 237
pituitary cancer 21 | 1,972
primitive neuroectodermal tumor 21 | 3,035
Liver Cirrhosis, Experimental 20 | 769
pancreatic carcinoma 20 | 562
Alzheimer's disease 19 | 658
Hepatitis B 19 | 108
active Crohn's disease 19 | 922
hepatocellular carcinoma 19 | 547
Autosomal recessive predisposition 18 | 1,442
Breast Neoplasms 18 | 445
Dermatitis 18 | 157
Fever 18 | 138
Major Depressive Disorder 18 | 301
Vasculitis 18 | 80
active ulcerative colitis 18 | 764
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
Atherosclerosis 17 | 291
Berylliosis 17 | 28
Endometriosis 17 | 540
Heart disease 17 | 306
Hepatitis C 17 | 94
Lung Neoplasms 17 | 232
Mammary Neoplasms 17 | 425
Myocardial Ischemia 17 | 169
Narcolepsy 17 | 72
Waldenstrons macroglobulinemia 17 | 765
adrenocortical carcinoma 17 | 1,428
colon cancer 17 | 1,478
nasopharyngeal carcinoma 17 | 1,058
Pick disease 16 | 1,894
Reperfusion Injury 16 | 86
Unipolar Depression 16 | 250
acute myeloid leukemia 16 | 783
follicular lymphoma 16 | 20
primary pancreatic ductal adenocarcinoma 16 | 1,109
Depressive disorder 15 | 409
Hyperglycemia 15 | 137
Inflammation 15 | 120
Melanoma 15 | 711
Microphthalmia with limb anomalies 15 | 40
Stomach Neoplasms 15 | 300
astrocytic glioma 15 | 2,597
esophageal adenocarcinoma 15 | 737

Tissue

Blood and immune system 155 | 16,909
Male tissues 155 | 17,142
Digestive Tract 152 | 17,369
Endocrine System 152 | 18,159
Respiratory system 152 | 16,393
Skin and soft tissues 152 | 17,230
Female tissues 151 | 17,400
Liver and Pancreas 151 | 16,750
Urinary Tract 151 | 16,678
Nervous System 149 | 16,725
Cardiovascular System 143 | 15,192

Target Family

Non-IDG 110 | 12,091
Kinase 38 | 634
Enzyme 22 | 4,145
Transcription Factor 9 | 1,400
Epigenetic 2 | 242
Transporter 1 | 473

KEGG Pathway

Influenza A 182 | 182
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NTF2-related export protein 1 NXT1 Tbio Non-IDG -1.49831 29.4 91
2'-5'-oligoadenylate synthase 3 OAS3 Tbio Enzyme -1.30083 17.8 141
Heterogeneous nuclear ribonucleoprotein U-like protein 1 HNRNPUL1 Tbio Non-IDG -0.99811 11.3 132
Embryonic polyadenylate-binding protein 2 PABPN1L Tdark Non-IDG -0.16137 1.83 53
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
Heat shock-related 70 kDa protein 2 HSPA2 Tbio Non-IDG -1.98655 104.3 162
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Tclin Kinase -3.07197 862.4 2448
Polyadenylate-binding protein 2 PABPN1 Tbio Non-IDG -2.48757 316.4 120
Transmembrane protease serine 13 TMPRSS13 Tbio Enzyme -1.77634 56.8 71