Development Level

Tchem 47 | 1,598
Tbio 26 | 11,445
Tclin 22 | 613
Tdark 4 | 6,588

Collection

Kinase: IDG Consortium (Target... 3 | 125
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

increased startle reflex 5 | 112
abnormal bone structure 4 | 187
decreased vertical activity 4 | 208
increased heart weight 4 | 62
preweaning lethality, incomple... 4 | 499
male infertility 3 | 123
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased body weight 2 | 161
decreased circulating creatini... 2 | 39
decreased total body fat amoun... 2 | 207
hydrometra 2 | 53
increased erythrocyte cell num... 2 | 39
increased lean body mass 2 | 172
increased total body fat amoun... 2 | 134
small superior vagus ganglion 2 | 74
abnormal bone mineralization 1 | 38
abnormal digit morphology 1 | 10
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal gallbladder morpholog... 1 | 1
abnormal locomotor behavior 1 | 24
abnormal testis morphology 1 | 43
abnormal vocalization 1 | 21
decreased IgG3 level 1 | 1
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased mature B cell number 1 | 7
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged gallbladder 1 | 2
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased IgG1 level 1 | 1
increased IgM level 1 | 1
increased T cell number 1 | 6
increased bone mineral content 1 | 108
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
small epididymis 1 | 3
small testis 1 | 58

Disease

Carcinoma 83 | 11,493
psoriasis 48 | 6,694
osteosarcoma 45 | 7,950
ovarian cancer 45 | 8,520
glioblastoma 44 | 5,792
lung cancer 40 | 4,740
medulloblastoma, large-cell 40 | 6,241
adult high grade glioma 38 | 3,801
Astrocytoma, Pilocytic 35 | 3,081
atypical teratoid / rhabdoid tumor 35 | 5,112
ependymoma 35 | 4,679
Cancer 34 | 2,499
group 3 medulloblastoma 29 | 4,104
Breast cancer 28 | 3,578
primitive neuroectodermal tumor 27 | 3,035
Kidney cancer 26 | 2,613
Schizophrenia 26 | 1,160
malignant mesothelioma 26 | 3,232
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
lung adenocarcinoma 24 | 2,716
lung carcinoma 24 | 2,843
oligodendroglioma 24 | 2,850
pancreatic cancer 23 | 2,398
interstitial cystitis 22 | 2,312
astrocytic glioma 21 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
subependymal giant cell astrocytoma 19 | 2,287
invasive ductal carcinoma 18 | 2,951
Bipolar Disorder 17 | 666
non-small cell lung cancer 17 | 2,890
tuberculosis 17 | 2,010
ulcerative colitis 17 | 1,819
Depressive disorder 16 | 409
cystic fibrosis 16 | 1,696
diabetes mellitus 16 | 1,728
pituitary cancer 16 | 1,972
Hyperalgesia 15 | 83
Obesity 15 | 678
colon cancer 15 | 1,478
Autosomal recessive predisposition 14 | 1,442
group 4 medulloblastoma 14 | 1,855
Pick disease 13 | 1,894
Rheumatoid arthritis 13 | 1,191
Alzheimer's disease 12 | 658
Epilepsy 12 | 792
Hypertension 12 | 396
Inflammation 11 | 120
Liver cancer 11 | 604
juvenile dermatomyositis 11 | 1,187
Asthma 10 | 385
Intellectual disability 10 | 1,016
Major Depressive Disorder 10 | 301
Mental Depression 10 | 333
Arthritis 9 | 290
Heart disease 9 | 306
Hyperactive behavior 9 | 91
Osteoporosis 9 | 363
Parkinson's disease 9 | 392
Unipolar Depression 9 | 250
Vascular disease 9 | 319
Waldenstrons macroglobulinemia 9 | 765
cutaneous lupus erythematosus 9 | 1,057
pancreatic carcinoma 9 | 562
spina bifida 9 | 1,074
Acquired metabolic disease 8 | 336
Alcoholic Intoxication, Chronic 8 | 289
Dull intelligence 8 | 645
Endometriosis 8 | 540
Hypertensive disease 8 | 292
Infantile onset 8 | 238
Kidney disease 8 | 430
Liver Cirrhosis, Experimental 8 | 769
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Neuropathy 8 | 261
Poor school performance 8 | 645
Seizures 8 | 596
Substance Withdrawal Syndrome 8 | 55
breast carcinoma 8 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Cardiomegaly 7 | 116
Cardiomyopathies 7 | 110
Cerebrovascular disease 7 | 238
Hypothyroidism 7 | 122
Melanoma 7 | 711
Neurodegenerative disease 7 | 414
Polycystic ovary syndrome 7 | 360
Toxic encephalopathy 7 | 141
adrenocortical carcinoma 7 | 1,428
dermatomyositis 7 | 966
ductal carcinoma in situ 7 | 1,745
esophageal adenocarcinoma 7 | 737
primary Sjogren syndrome 7 | 735
substance-related disorder 7 | 162
Attention deficit hyperactivity disorder 6 | 278
Crohn's disease 6 | 321
Migraine 6 | 83
aldosterone-producing adenoma 6 | 665

Tissue

Endocrine System 94 | 18,159
Female tissues 94 | 17,400
Male tissues 94 | 17,142
Skin and soft tissues 94 | 17,230
Digestive Tract 93 | 17,369
Blood and immune system 92 | 16,909
Nervous System 91 | 16,725
Liver and Pancreas 90 | 16,750
Respiratory system 89 | 16,393
Urinary Tract 88 | 16,678
Cardiovascular System 85 | 15,192

Target Family

Kinase 29 | 634
Enzyme 28 | 4,145
Non-IDG 18 | 12,091
Ion Channel 14 | 344
GPCR 10 | 408

KEGG Pathway

Inflammatory mediator regulati... 99 | 99
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.28525 197.9 203
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Acid-sensing ion channel 5 ASIC5 Tbio Ion Channel -0.41218 3.22 86
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
5-hydroxytryptamine receptor 2B HTR2B Tclin GPCR -2.66641 486.3 265
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Acid-sensing ion channel 3 ASIC3 Tchem Ion Channel -2.28745 195.8 130
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344