Development Level

Tbio 50 | 11,445
Tchem 15 | 1,598
Tclin 11 | 613
Tdark 1 | 6,588

IMPC Phenotype

increased neutrophil cell numb... 3 | 46
abnormal heart morphology 2 | 162
decreased lymphocyte cell numb... 2 | 83
enlarged heart 2 | 210
enlarged lymph nodes 2 | 37
increased monocyte cell number 2 | 63
abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal eye anterior chamber ... 1 | 9
abnormal gait 1 | 69
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased heart weight 1 | 27
decreased large unstained cell... 1 | 11
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged testis 1 | 6
enlarged uterus 1 | 11
impaired righting response 1 | 26
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased eosinophil cell numb... 1 | 11
increased erythrocyte cell num... 1 | 39
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
small superior vagus ganglion 1 | 74
vertebral fusion 1 | 23

Disease

psoriasis 43 | 6,694
Rheumatoid arthritis 39 | 1,191
Cancer 36 | 2,499
Carcinoma 35 | 11,493
tuberculosis 33 | 2,010
Multiple Sclerosis 32 | 540
diabetes mellitus 32 | 1,728
Asthma 31 | 385
Hypersensitivity reaction type II disease 31 | 253
lung cancer 30 | 4,740
Inflammatory bowel disease 29 | 151
lung carcinoma 29 | 2,843
glioblastoma 27 | 5,792
Arthritis 26 | 290
sarcoidosis 26 | 370
ovarian cancer 25 | 8,520
ulcerative colitis 25 | 1,819
malignant mesothelioma 24 | 3,232
osteosarcoma 24 | 7,950
Dermatitis 23 | 157
Schizophrenia 23 | 1,160
interstitial cystitis 22 | 2,312
Kidney disease 20 | 430
Astrocytoma, Pilocytic 19 | 3,081
Pneumonia 19 | 174
Systemic lupus erythematosus 19 | 194
Berylliosis 18 | 28
Liver disease 18 | 237
Allergic hypersensitivity disease 17 | 126
Crohn's disease 17 | 321
Narcolepsy 17 | 72
Vasculitis 17 | 80
invasive ductal carcinoma 17 | 2,951
Breast cancer 16 | 3,578
adult high grade glioma 16 | 3,801
cutaneous lupus erythematosus 16 | 1,057
non-small cell lung cancer 16 | 2,890
Arthritis, Rheumatoid 15 | 174
Fever 15 | 138
Hepatitis B 15 | 108
Inflammation 15 | 120
Lung disease 15 | 142
lung adenocarcinoma 15 | 2,716
Allergic rhinitis 14 | 94
Candidiasis 14 | 55
Hypereosinophilic syndrome 14 | 71
Hypersensitivity 14 | 63
Leishmaniasis 14 | 47
Multiple Sclerosis, Susceptibility to 14 | 15
Narcolepsy-cataplexy 14 | 21
Pulmonary Fibrosis 14 | 106
Rheumatoid Arthritis, Systemic Juvenile 14 | 16
Sarcoidosis 1 14 | 14
atypical teratoid / rhabdoid tumor 14 | 5,112
breast carcinoma 14 | 1,638
cystic fibrosis 14 | 1,696
ependymoma 14 | 4,679
pancreatic cancer 14 | 2,398
periodontitis 14 | 293
Bipolar Disorder 13 | 666
Diffuse cutaneous systemic sclerosis 13 | 17
Influenza 13 | 142
Leprosy 13 | 73
follicular lymphoma 13 | 20
limited scleroderma 13 | 19
subependymal giant cell astrocytoma 13 | 2,287
Brain Ischemia 12 | 110
Collagen disease 12 | 27
Coronary artery disease 12 | 268
Heart disease 12 | 306
Liver Cirrhosis, Experimental 12 | 769
Malaria 12 | 160
esophageal adenocarcinoma 12 | 737
medulloblastoma, large-cell 12 | 6,241
Atherosclerosis 11 | 291
Brain Injuries 11 | 65
Chemical and Drug Induced Liver Injury 11 | 195
Reperfusion Injury 11 | 86
Type 1 diabetes mellitus 11 | 109
Uveitis 11 | 103
active Crohn's disease 11 | 922
astrocytoma 11 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
pituitary cancer 11 | 1,972
Arthritis, Experimental 10 | 39
Celiac disease 10 | 116
Colitis, Ulcerative 10 | 59
Common cold 10 | 67
Crohn Disease 10 | 45
Diarrhea 10 | 253
Hepatitis, Autoimmune 10 | 17
Hypertensive disease 10 | 292
Juvenile rheumatoid arthritis 10 | 111
Lupus Erythematosus, Systemic 10 | 67
Psoriatic arthritis 10 | 86
Waldenstrons macroglobulinemia 10 | 765
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
dermatomyositis 9 | 966
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962

Tissue

Blood and immune system 62 | 16,909
Digestive Tract 61 | 17,369
Skin and soft tissues 60 | 17,230
Urinary Tract 60 | 16,678
Endocrine System 59 | 18,159
Liver and Pancreas 59 | 16,750
Male tissues 59 | 17,142
Respiratory system 58 | 16,393
Female tissues 56 | 17,400
Nervous System 51 | 16,725
Cardiovascular System 50 | 15,192

Target Family

Non-IDG 61 | 12,091
Transcription Factor 14 | 1,400
Nuclear Receptor 2 | 48

KEGG Pathway

Inflammatory bowel disease (IB... 77 | 77
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

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