Development Level

Tbio 50 | 11,445
Tchem 32 | 1,598
Tclin 9 | 613
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to t... 3 | 278
abnormal heart morphology 2 | 162
decreased vertical activity 2 | 208
enlarged heart 2 | 210
increased erythrocyte cell num... 2 | 39
preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal snout morphology 1 | 23
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating creatini... 1 | 39
decreased circulating sodium l... 1 | 22
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
hyperactivity 1 | 148
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased grip strength 1 | 41
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9
male infertility 1 | 123
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

psoriasis 67 | 6,694
Cancer 65 | 2,499
ovarian cancer 48 | 8,520
Carcinoma 47 | 11,493
lung cancer 43 | 4,740
glioblastoma 40 | 5,792
osteosarcoma 32 | 7,950
Asthma 31 | 385
medulloblastoma, large-cell 31 | 6,241
tuberculosis 31 | 2,010
Arthritis 28 | 290
atypical teratoid / rhabdoid tumor 28 | 5,112
ependymoma 28 | 4,679
lung adenocarcinoma 28 | 2,716
Inflammatory bowel disease 26 | 151
non-small cell lung cancer 26 | 2,890
ulcerative colitis 26 | 1,819
Schizophrenia 25 | 1,160
interstitial cystitis 24 | 2,312
lung carcinoma 24 | 2,843
Breast cancer 23 | 3,578
Lung disease 23 | 142
cystic fibrosis 23 | 1,696
diabetes mellitus 23 | 1,728
malignant mesothelioma 23 | 3,232
Pneumonia 21 | 174
Rheumatoid arthritis 21 | 1,191
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
pancreatic cancer 21 | 2,398
Breast Neoplasms 20 | 445
Mammary Neoplasms 20 | 425
Brain Ischemia 19 | 110
Dermatitis 19 | 157
Multiple Sclerosis 19 | 540
invasive ductal carcinoma 19 | 2,951
adult high grade glioma 18 | 3,801
periodontitis 18 | 293
Astrocytoma, Pilocytic 17 | 3,081
Hypersensitivity reaction type II disease 17 | 253
Kidney disease 17 | 430
Vascular disease 17 | 319
Bipolar Disorder 16 | 666
Liver Cirrhosis, Experimental 16 | 769
Reperfusion Injury 16 | 86
colon cancer 16 | 1,478
Atherosclerosis 15 | 291
Common cold 15 | 67
Heart disease 15 | 306
Hypertension 15 | 396
Inflammation 15 | 120
Obesity 15 | 678
breast carcinoma 15 | 1,638
cutaneous lupus erythematosus 15 | 1,057
group 3 medulloblastoma 15 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
pituitary cancer 15 | 1,972
Allergic hypersensitivity disease 14 | 126
Hypereosinophilic syndrome 14 | 71
Hypersensitivity 14 | 63
Liver disease 14 | 237
Lung Neoplasms 14 | 232
Pulmonary Fibrosis 14 | 106
astrocytoma 14 | 1,146
subependymal giant cell astrocytoma 14 | 2,287
Allergic rhinitis 13 | 94
Alzheimer's disease 13 | 658
Brain Injuries 13 | 65
Hyperalgesia 13 | 83
Neoplasm Metastasis 13 | 168
esophageal adenocarcinoma 13 | 737
group 4 medulloblastoma 13 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Arthritis, Rheumatoid 12 | 174
Chemical and Drug Induced Liver Injury 12 | 195
Cholestasis, Extrahepatic 12 | 25
Influenza 12 | 142
Multiple myeloma 12 | 1,332
Parkinson's disease 12 | 392
Toxic encephalopathy 12 | 141
acute myeloid leukemia 12 | 783
hepatocellular carcinoma 12 | 547
nasopharyngeal carcinoma 12 | 1,058
Candidiasis 11 | 55
Cerebrovascular disease 11 | 238
Colonic Neoplasms 11 | 142
Coronary artery disease 11 | 268
Depressive disorder 11 | 409
Dermatitis, Atopic 11 | 37
Eye disease 11 | 62
Hypertensive disease 11 | 292
Leishmaniasis 11 | 47
Major Depressive Disorder 11 | 301
Malaria 11 | 160
Prostatic Neoplasms 11 | 495
Waldenstrons macroglobulinemia 11 | 765
acute quadriplegic myopathy 11 | 1,158
oligodendroglioma 11 | 2,850
primitive neuroectodermal tumor 11 | 3,035
ductal carcinoma in situ 10 | 1,745

Tissue

Blood and immune system 91 | 16,909
Digestive Tract 91 | 17,369
Liver and Pancreas 90 | 16,750
Urinary Tract 90 | 16,678
Endocrine System 89 | 18,159
Female tissues 89 | 17,400
Respiratory system 89 | 16,393
Skin and soft tissues 89 | 17,230
Male tissues 87 | 17,142
Nervous System 79 | 16,725
Cardiovascular System 74 | 15,192

Target Family

Non-IDG 53 | 12,091
Kinase 20 | 634
Enzyme 11 | 4,145
Transcription Factor 8 | 1,400

KEGG Pathway

IL-17 signaling pathway 92 | 92
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mucin-5B MUC5B Tbio Non-IDG -3.20322 1552.2 177
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
TNF receptor-associated factor 4 TRAF4 Tbio Non-IDG -1.67380 54.4 234
CCAAT/enhancer-binding protein beta CEBPB Tbio Transcription Factor -2.96589 857.9 436
C-C motif chemokine 2 CCL2 Tchem Non-IDG -3.84820 7088.3 1260
Adapter protein CIKS TRAF3IP2 Tbio Non-IDG -1.81845 71.6 360
Endoplasmin HSP90B1 Tchem Non-IDG -2.76074 629.2 850
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731
Eotaxin CCL11 Tbio Non-IDG -2.99518 992.7 285
Fos-related antigen 1 FOSL1 Tbio Transcription Factor -2.39870 235.8 243