Development Level

Tbio 55 | 11,445
Tclin 15 | 613
Tchem 9 | 1,598
Tdark 4 | 6,588

Collection

Ion Channel: IDG Consortium (T... 14 | 99

IMPC Phenotype

preweaning lethality, complete... 8 | 979
embryonic lethality prior to t... 4 | 278
abnormal embryo size 3 | 220
decreased circulating glucose ... 3 | 126
decreased mean platelet volume 3 | 25
increased startle reflex 3 | 112
preweaning lethality, incomple... 3 | 499
abnormal heart morphology 2 | 162
abnormal response to new envir... 2 | 10
decreased circulating amylase ... 2 | 28
decreased eosinophil cell numb... 2 | 24
decreased mean corpuscular vol... 2 | 79
edema 2 | 59
embryonic growth retardation 2 | 106
enlarged spleen 2 | 41
hemorrhage 2 | 23
impaired glucose tolerance 2 | 75
increased circulating sodium l... 2 | 71
increased circulating triglyce... 2 | 42
increased mean platelet volume 2 | 45
prolonged PR interval 2 | 15
abnormal behavior 1 | 298
abnormal facial morphology 1 | 17
abnormal lens morphology 1 | 81
abnormal placenta vasculature 1 | 2
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal thymus morphology 1 | 7
anophthalmia 1 | 33
cataract 1 | 92
cyanosis 1 | 7
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged thymus 1 | 5
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating chloride... 1 | 41
increased glycosylated hemoglo... 1 | 1
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
pallor 1 | 34
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged ST segment 1 | 36
respiratory system phenotype 1 | 2
tremors 1 | 39
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 65 | 11,493
glioblastoma 45 | 5,792
osteosarcoma 40 | 7,950
psoriasis 37 | 6,694
ovarian cancer 36 | 8,520
atypical teratoid / rhabdoid tumor 34 | 5,112
medulloblastoma, large-cell 33 | 6,241
adult high grade glioma 30 | 3,801
ependymoma 28 | 4,679
Astrocytoma, Pilocytic 27 | 3,081
Autosomal recessive predisposition 27 | 1,442
lung cancer 26 | 4,740
lung carcinoma 26 | 2,843
Kidney cancer 24 | 2,613
Breast cancer 22 | 3,578
Cardiomyopathy 21 | 116
lung adenocarcinoma 21 | 2,716
pancreatic cancer 21 | 2,398
Cancer 20 | 2,499
non-small cell lung cancer 20 | 2,890
primitive neuroectodermal tumor 20 | 3,035
malignant mesothelioma 19 | 3,232
Myopathy 18 | 185
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
invasive ductal carcinoma 18 | 2,951
oligodendroglioma 18 | 2,850
colon cancer 17 | 1,478
group 3 medulloblastoma 17 | 4,104
Cardiomyopathy, Dilated 16 | 83
Schizophrenia 16 | 1,160
group 4 medulloblastoma 16 | 1,855
Bipolar Disorder 15 | 666
Dilated cardiomyopathy 15 | 56
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
Heart disease 14 | 306
Heart failure 14 | 162
astrocytic glioma 14 | 2,597
cystic fibrosis 14 | 1,696
diabetes mellitus 14 | 1,728
interstitial cystitis 14 | 2,312
tuberculosis 14 | 2,010
Coronary artery disease 13 | 268
Hypertensive disease 13 | 292
Hypertrophic Cardiomyopathy 13 | 117
acute quadriplegic myopathy 13 | 1,158
pituitary cancer 13 | 1,972
Congestive heart failure 12 | 113
Familial isolated dilated cardiomyopathy 12 | 41
LEFT VENTRICULAR NONCOMPACTION 10 12 | 40
LEFT VENTRICULAR NONCOMPACTION 8 12 | 40
Liver Cirrhosis, Experimental 12 | 769
subependymal giant cell astrocytoma 12 | 2,287
Cardiomyopathies 11 | 110
Cerebrovascular accident 11 | 63
Cerebrovascular disease 11 | 238
Creatine phosphokinase serum increased 11 | 110
Elevated creatine kinase 11 | 110
Hypertension 11 | 396
Muscular dystrophy 11 | 75
Myocardial Infarction 11 | 151
Pick disease 11 | 1,894
ductal carcinoma in situ 11 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
primary pancreatic ductal adenocarcinoma 11 | 1,109
ulcerative colitis 11 | 1,819
Acquired scoliosis 10 | 281
Acute coronary syndrome 10 | 39
Cardiomegaly 10 | 116
Curvature of spine 10 | 282
Liver cancer 10 | 604
Muscle hypotonia 10 | 571
Prenatal onset 10 | 139
Stomach Neoplasms 10 | 300
Cardiac Arrhythmia 9 | 103
Duchenne muscular dystrophy 9 | 601
Endometriosis 9 | 540
Intellectual disability 9 | 1,016
Melanoma 9 | 711
Muscle biopsy shows dystrophic changes 9 | 39
Skin cancer 9 | 469
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
pediatric high grade glioma 9 | 1,064
Atrial Fibrillation 8 | 124
Epilepsy 8 | 792
Left ventricular noncompaction 8 | 26
Mental Depression 8 | 333
Neoplasm Invasiveness 8 | 161
Neoplasm Metastasis 8 | 168
Osteoporosis 8 | 363
Rheumatoid arthritis 8 | 1,191
Stroke 8 | 33
dermatomyositis 8 | 966
limb-girdle muscular dystrophy 8 | 37
Alzheimer's disease 7 | 658
Depressive disorder 7 | 409
Myocardial Ischemia 7 | 169
adrenocortical carcinoma 7 | 1,428
astrocytoma 7 | 1,146
breast carcinoma 7 | 1,638

Tissue

Endocrine System 83 | 18,159
Digestive Tract 81 | 17,369
Male tissues 80 | 17,142
Nervous System 80 | 16,725
Female tissues 79 | 17,400
Skin and soft tissues 79 | 17,230
Blood and immune system 78 | 16,909
Urinary Tract 76 | 16,678
Liver and Pancreas 75 | 16,750
Respiratory system 74 | 16,393
Cardiovascular System 72 | 15,192

Target Family

Non-IDG 50 | 12,091
Ion Channel 21 | 344
Enzyme 5 | 4,145
Kinase 5 | 634
Transporter 2 | 473

KEGG Pathway

Hypertrophic cardiomyopathy (H... 83 | 83
Metabolic pathways 1,263 | 1,263
Pathways in cancer 530 | 530
Olfactory transduction 414 | 414
Human papillomavirus infection 388 | 388
PI3K-Akt signaling pathway 349 | 349
HTLV-I infection 336 | 336
Endocytosis 310 | 310
MAPK signaling pathway 295 | 295
Epstein-Barr virus infection 280 | 280
Neuroactive ligand-receptor in... 276 | 276
Cytokine-cytokine receptor int... 267 | 267
Herpes simplex infection 262 | 262
Kaposi's sarcoma-associated he... 252 | 252
Viral carcinogenesis 251 | 251
Thermogenesis 232 | 232
Ras signaling pathway 230 | 230
Phagosome 229 | 229
Cellular senescence 228 | 228
Cell adhesion molecules (CAMs) 225 | 225
Rap1 signaling pathway 209 | 209
Regulation of actin cytoskelet... 207 | 207
cAMP signaling pathway 201 | 201
Focal adhesion 198 | 198
Proteoglycans in cancer 198 | 198
Natural killer cell mediated c... 197 | 197
Huntington's disease 194 | 194
Tuberculosis 189 | 189
Calcium signaling pathway 183 | 183
Chemokine signaling pathway 183 | 183
Influenza A 182 | 182
Axon guidance 174 | 174
Purine metabolism 172 | 172
Alzheimer's disease 171 | 171
Transcriptional misregulation ... 171 | 171
Tight junction 169 | 169
Hepatocellular carcinoma 168 | 168
NOD-like receptor signaling pa... 166 | 166
Protein processing in endoplas... 164 | 164
RNA transport 163 | 163
cGMP-PKG signaling pathway 162 | 162
Jak-STAT signaling pathway 161 | 161
Cushing's syndrome 158 | 158
Antigen processing and present... 156 | 156
Hippo signaling pathway 154 | 154
Necroptosis 154 | 154
Oxytocin signaling pathway 154 | 154
MicroRNAs in cancer 150 | 150
mTOR signaling pathway 150 | 150
Non-alcoholic fatty liver dise... 149 | 149
Gastric cancer 148 | 148
Retrograde endocannabinoid sig... 148 | 148
Adrenergic signaling in cardio... 147 | 147
Alcoholism 147 | 147
Breast cancer 147 | 147
Phospholipase D signaling path... 147 | 147
Wnt signaling pathway 145 | 145
Hepatitis B 143 | 143
Parkinson's disease 142 | 142
Estrogen signaling pathway 139 | 139
Apoptosis 138 | 138
Fluid shear stress and atheros... 138 | 138
Signaling pathways regulating ... 138 | 138
Insulin signaling pathway 137 | 137
Ubiquitin mediated proteolysis 137 | 137
Viral myocarditis 137 | 137
Apelin signaling pathway 136 | 136
Dopaminergic synapse 135 | 135
Ribosome 134 | 134
Measles 133 | 133
Oxidative phosphorylation 133 | 133
Relaxin signaling pathway 133 | 133
Spliceosome 132 | 132
Autoimmune thyroid disease 130 | 130
FoxO signaling pathway 130 | 130
Hepatitis C 130 | 130
Autophagy - animal 128 | 128
Osteoclast differentiation 127 | 127
Cell cycle 125 | 125
Platelet activation 125 | 125
Toxoplasmosis 125 | 125
Lysosome 123 | 123
Vascular smooth muscle contrac... 123 | 123
Type I diabetes mellitus 122 | 122
Oocyte meiosis 121 | 121
AMPK signaling pathway 120 | 120
Graft-versus-host disease 120 | 120
Neurotrophin signaling pathway 119 | 119
Th17 cell differentiation 119 | 119
Sphingolipid signaling pathway 118 | 118
Allograft rejection 116 | 116
Carbon metabolism 116 | 116
Glutamatergic synapse 116 | 116
Thyroid hormone signaling path... 116 | 116
Serotonergic synapse 114 | 114
Leukocyte transendothelial mig... 112 | 112
Cholinergic synapse 111 | 111
Hematopoietic cell lineage 108 | 108
Systemic lupus erythematosus 108 | 108
TNF signaling pathway 108 | 108
Insulin resistance 107 | 107

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 ATP2A2 Tbio Transporter -2.87498 737.3 295
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 Tbio Ion Channel -1.46356 25.4 471
Myosin-6 MYH6 Tbio Non-IDG -2.95952 901.3 45
Emerin EMD Tbio Non-IDG -2.80459 640.6 299
Actin, cytoplasmic 2 ACTG1 Tbio Non-IDG -2.50312 297.3 225
Titin TTN Tbio Kinase -3.24415 1743.0 123
Integrin alpha-7 ITGA7 Tbio Non-IDG -1.63563 42.4 193
Tropomyosin alpha-4 chain TPM4 Tbio Non-IDG -1.57899 37.4 120